A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction G Pelicci, L Lanfrancone, F Grignani, J McGlade, F Cavallo, G Forni, ... Cell 70 (1), 93-104, 1992 | 1688 | 1992 |
Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases M Rozakis-Adcock, J McGlade, G Mbamalu, G Pelicci, R Daly, W Li, ... Nature 360 (6405), 689-692, 1992 | 1243 | 1992 |
Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav Z Songyang, SE Shoelson, J McGlade, P Olivier, T Pawson, XR Bustelo, ... Molecular and cellular biology 14 (4), 2777-2785, 1994 | 1191 | 1994 |
WW domains of Nedd4 bind to the proline‐rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome. O Staub, S Dho, P Henry, J Correa, T Ishikawa, J McGlade, D Rotin The EMBO journal 15 (10), 2371-2380, 1996 | 1057 | 1996 |
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies SC Bunnell, DI Hong, JR Kardon, T Yamazaki, CJ McGlade, VA Barr, ... The Journal of cell biology 158 (7), 1263-1275, 2002 | 748 | 2002 |
The basic science of oncology IF Tannock, RP Hill The basic science of oncology, 420-420, 1992 | 722 | 1992 |
Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B A Cheng, N Uetani, PD Simoncic, VP Chaubey, A Lee-Loy, CJ McGlade, ... Developmental cell 2 (4), 497-503, 2002 | 682 | 2002 |
Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity L Salmena, B Lemmers, A Hakem, E Matysiak-Zablocki, K Murakami, ... Genes & development 17 (7), 883-895, 2003 | 594 | 2003 |
Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain MA McGill, CJ McGlade Journal of Biological Chemistry 278 (25), 23196-23203, 2003 | 587 | 2003 |
Integrin β cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling DA Calderwood, Y Fujioka, JM de Pereda, B García-Alvarez, T Nakamoto, ... Proceedings of the National Academy of Sciences 100 (5), 2272-2277, 2003 | 541 | 2003 |
Association of Grb2, Gads, and phospholipase C-γ1 with phosphorylated LAT tyrosine residues: effect of LAT tyrosine mutations on T cell antigen receptor-mediated signaling W Zhang, RP Trible, M Zhu, SK Liu, CJ McGlade, LE Samelson Journal of Biological Chemistry 275 (30), 23355-23361, 2000 | 535 | 2000 |
Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis M Pellikka, G Tanentzapf, M Pinto, C Smith, CJ McGlade, DF Ready, ... Nature 416 (6877), 143-149, 2002 | 485 | 2002 |
The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors SK Liu, N Fang, GA Koretzky, CJ McGlade Current Biology 9 (2), 67-75, 1999 | 453 | 1999 |
The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3 PD Simoncic, A Lee-Loy, DL Barber, ML Tremblay, CJ McGlade Current biology 12 (6), 446-453, 2002 | 410 | 2002 |
Insulin-induced phosphorylation of the 46-and 52-kDa Shc proteins. GJ Pronk, J McGlade, G Pelicci, T Pawson, JL Bos Journal of Biological Chemistry 268 (8), 5748-5753, 1993 | 386 | 1993 |
Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases. J Mcglade, A Cheng, G Pelicci, PG Pelicci, T Pawson Proceedings of the National Academy of Sciences 89 (19), 8869-8873, 1992 | 356 | 1992 |
Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein PA Garrity, Y Rao, I Salecker, J McGlade, T Pawson, SL Zipursky Cell 85 (5), 639-650, 1996 | 336 | 1996 |
The N‐terminal region of GAP regulates cytoskeletal structure and cell adhesion. J McGlade, B Brunkhorst, D Anderson, G Mbamalu, J Settleman, ... The EMBO Journal 12 (8), 3073-3081, 1993 | 287 | 1993 |
Formation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins AE Salcini, J McGlade, G Pelicci, I Nicoletti, T Pawson, PG Pelicci Nature Publishing Group, 1994 | 286 | 1994 |
aPKC‐mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb CA Smith, KM Lau, Z Rahmani, SE Dho, G Brothers, YM She, DM Berry, ... The EMBO journal 26 (2), 468-480, 2007 | 284 | 2007 |