| Identifying a high fraction of the human genome to be under selective constraint using GERP++ EV Davydov, DL Goode, M Sirota, GM Cooper, A Sidow, S Batzoglou PLoS Comput Biol 6 (12), e1001025, 2010 | 1968 | 2010 |
| Dissecting virulence: systematic and functional analyses of a pathogenicity island W Deng, JL Puente, S Gruenheid, Y Li, BA Vallance, A Vázquez, J Barba, ... Proceedings of the National Academy of Sciences 101 (10), 3597-3602, 2004 | 752 | 2004 |
| The origin, evolution, and functional impact of short insertion–deletion variants identified in 179 human genomes SB Montgomery, DL Goode, E Kvikstad, CA Albers, ZD Zhang, XJ Mu, ... Genome research 23 (5), 749-761, 2013 | 290 | 2013 |
| Identification and characterization of NleA, a non‐LEE‐encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157: H7 S Gruenheid, I Sekirov, NA Thomas, W Deng, P O'Donnell, D Goode, Y Li, ... Molecular microbiology 51 (5), 1233-1249, 2004 | 285 | 2004 |
| Monogenic and polygenic determinants of sarcoma risk: an international genetic study ML Ballinger, DL Goode, I Ray-Coquard, PA James, G Mitchell, ... The Lancet Oncology 17 (9), 1261-1271, 2016 | 237 | 2016 |
| Single-nucleotide evolutionary constraint scores highlight disease-causing mutations GM Cooper, DL Goode, SB Ng, A Sidow, MJ Bamshad, J Shendure, ... Nature methods 7 (4), 250-251, 2010 | 225 | 2010 |
| Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors AS Trigos, RB Pearson, AT Papenfuss, DL Goode Proceedings of the National Academy of Sciences 114 (24), 6406-6411, 2017 | 212 | 2017 |
| Loss of heterozygosity: what is it good for? GL Ryland, MA Doyle, D Goode, SE Boyle, DYH Choong, SM Rowley, J Li, ... BMC medical genomics 8 (1), 45, 2015 | 188 | 2015 |
| Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia CC Bell, KA Fennell, YC Chan, F Rambow, MM Yeung, D Vassiliadis, ... Nature communications 10 (1), 2723, 2019 | 173 | 2019 |
| Reconstructing an ancestral mammalian immune supercomplex from a marsupial major histocompatibility complex K Belov, JE Deakin, AT Papenfuss, ML Baker, SD Melman, HV Siddle, ... PLoS biology 4 (3), e46, 2006 | 167 | 2006 |
| How the evolution of multicellularity set the stage for cancer AS Trigos, RB Pearson, AT Papenfuss, DL Goode British journal of cancer, 2018 | 153 | 2018 |
| The H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential SHK Wong, DL Goode, M Iwasaki, MC Wei, HP Kuo, L Zhu, ... Cancer cell, 2015 | 133 | 2015 |
| Proteomic analysis of the intestinal epithelial cell response to enteropathogenic Escherichia coli PR Hardwidge, I Rodriguez-Escudero, D Goode, S Donohoe, J Eng, ... Journal of Biological Chemistry 279 (19), 20127-20136, 2004 | 112 | 2004 |
| Patient-derived models of abiraterone-and enzalutamide-resistant prostate cancer reveal sensitivity to ribosome-directed therapy MG Lawrence, D Obinata, S Sandhu, LA Selth, SQ Wong, LH Porter, ... European urology 74 (5), 562-572, 2018 | 107 | 2018 |
| SseK1 and SseK2 are novel translocated proteins of Salmonella enterica serovar typhimurium SLK Choy, EC Boyle, O Gal-Mor, DL Goode, Y Valdez, BA Vallance, ... Infection and immunity 72 (9), 5115-5125, 2004 | 102 | 2004 |
| ArrayPipe: a flexible processing pipeline for microarray data K Hokamp, FM Roche, M Acab, ME Rousseau, B Kuo, D Goode, ... Nucleic acids research 32 (suppl 2), W457-W459, 2004 | 102 | 2004 |
| MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer A Cipponi, DL Goode, J Bedo, MJ McCabe, M Pajic, DR Croucher, ... Science 368 (6495), 1127-1131, 2020 | 101 | 2020 |
| Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes DL Goode, GM Cooper, J Schmutz, M Dickson, E Gonzales, M Tsai, ... Genome research 20 (3), 301-310, 2010 | 91 | 2010 |
| Somatic mutations in early metazoan genes disrupt regulatory links between unicellular and multicellular genes in cancer AS Trigos, RB Pearson, AT Papenfuss, DL Goode eLife 8, e40947, 2019 | 75 | 2019 |
| High Frequency of Germline TP53 Mutations in a Prospective Adult-Onset Sarcoma Cohort G Mitchell, ML Ballinger, S Wong, C Hewitt, P James, MA Young, ... PloS one 8 (7), e69026, 2013 | 75 | 2013 |
