Lysine‐targeting covalent inhibitors J Pettinger, K Jones, MD Cheeseman Angewandte Chemie International Edition 56 (48), 15200-15209, 2017 | 219 | 2017 |
An irreversible inhibitor of HSP72 that unexpectedly targets lysine‐56 J Pettinger, YV Le Bihan, M Widya, RLM Van Montfort, K Jones, ... Angewandte Chemie 129 (13), 3590-3594, 2017 | 74 | 2017 |
Kinetic optimization of lysine-targeting covalent inhibitors of HSP72 J Pettinger, M Carter, K Jones, MD Cheeseman Journal of Medicinal Chemistry 62 (24), 11383-11398, 2019 | 52 | 2019 |
Profiling sulfur (VI) fluorides as reactive functionalities for chemical biology tools and expansion of the ligandable proteome KE Gilbert, A Vuorinen, A Aatkar, P Pogány, J Pettinger, EK Grant, ... ACS chemical biology 18 (2), 285-295, 2023 | 40 | 2023 |
Novel WRN helicase inhibitors selectively target microsatellite-unstable cancer cells G Picco, Y Rao, A Al Saedi, Y Lee, SF Vieira, S Bhosle, K May, ... Cancer discovery 14 (8), 1457-1475, 2024 | 15 | 2024 |
A chemoproteomic platform for selective deubiquitinase inhibitor discovery R Cookson, A Vuorinen, J Pettinger, CR Kennedy, JM Kirkpatrick, ... Cell Reports Physical Science 4 (10), 2023 | 9 | 2023 |
Photochemical synthesis of cyclic peptide models from phthalimido acetamides and phthaloyl dipeptide esters K Krüger, V Lüdke, J Pettinger, L Ashton, L Bonnet, CA Motti, J Lex, ... Tetrahedron Letters 59 (14), 1427-1430, 2018 | 6 | 2018 |
Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics GS Biggs, EE Cawood, A Vuorinen, WJ McCarthy, H Wilders, IG Riziotis, ... Nature Communications 16 (1), 73, 2025 | 5 | 2025 |
One-pot oxidative amidation of aldehydes via the generation of nitrile imine intermediates MC Henry, L Minty, ACW Kwok, JML Elwood, AJ Foulis, J Pettinger, ... The Journal of Organic Chemistry 89 (11), 7913-7926, 2024 | 4 | 2024 |
Expedited SARS‐CoV‐2 Main Protease Inhibitor Discovery through Modular ‘Direct‐to‐Biology’Screening H Wilders, G Biggs, SM Rowe, EE Cawood, IG Riziotis, AR Rendina, ... Angewandte Chemie International Edition, e202418314, 2024 | 3 | 2024 |
Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation A Vuorinen, CR Kennedy, KA McPhie, W McCarthy, J Pettinger, ... Communications Chemistry 8 (1), 12, 2025 | 1 | 2025 |
‘Direct-to-biology’drives optimisation of a cell-active covalent inhibitor of WRN helicase SM Rowe, A Price, DJ Murphy, J Lin, EN Nartey, A Chaikuad, K Wong, ... | | 2025 |
ID: 204–P1. 011| Assessment of the bioorthogonality of the nitrile imine 1, 3-dipole M Gibson, K Livingstone, J Pettinger, C Jamieson Journal of Peptide Science 30 (S2), 82, 2024 | | 2024 |