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Jonathan Pettinger
Jonathan Pettinger
Zweryfikowany adres z gsk.com
Tytuł
Cytowane przez
Cytowane przez
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Lysine‐targeting covalent inhibitors
J Pettinger, K Jones, MD Cheeseman
Angewandte Chemie International Edition 56 (48), 15200-15209, 2017
2192017
An irreversible inhibitor of HSP72 that unexpectedly targets lysine‐56
J Pettinger, YV Le Bihan, M Widya, RLM Van Montfort, K Jones, ...
Angewandte Chemie 129 (13), 3590-3594, 2017
742017
Kinetic optimization of lysine-targeting covalent inhibitors of HSP72
J Pettinger, M Carter, K Jones, MD Cheeseman
Journal of Medicinal Chemistry 62 (24), 11383-11398, 2019
522019
Profiling sulfur (VI) fluorides as reactive functionalities for chemical biology tools and expansion of the ligandable proteome
KE Gilbert, A Vuorinen, A Aatkar, P Pogány, J Pettinger, EK Grant, ...
ACS chemical biology 18 (2), 285-295, 2023
402023
Novel WRN helicase inhibitors selectively target microsatellite-unstable cancer cells
G Picco, Y Rao, A Al Saedi, Y Lee, SF Vieira, S Bhosle, K May, ...
Cancer discovery 14 (8), 1457-1475, 2024
152024
A chemoproteomic platform for selective deubiquitinase inhibitor discovery
R Cookson, A Vuorinen, J Pettinger, CR Kennedy, JM Kirkpatrick, ...
Cell Reports Physical Science 4 (10), 2023
92023
Photochemical synthesis of cyclic peptide models from phthalimido acetamides and phthaloyl dipeptide esters
K Krüger, V Lüdke, J Pettinger, L Ashton, L Bonnet, CA Motti, J Lex, ...
Tetrahedron Letters 59 (14), 1427-1430, 2018
62018
Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics
GS Biggs, EE Cawood, A Vuorinen, WJ McCarthy, H Wilders, IG Riziotis, ...
Nature Communications 16 (1), 73, 2025
52025
One-pot oxidative amidation of aldehydes via the generation of nitrile imine intermediates
MC Henry, L Minty, ACW Kwok, JML Elwood, AJ Foulis, J Pettinger, ...
The Journal of Organic Chemistry 89 (11), 7913-7926, 2024
42024
Expedited SARS‐CoV‐2 Main Protease Inhibitor Discovery through Modular ‘Direct‐to‐Biology’Screening
H Wilders, G Biggs, SM Rowe, EE Cawood, IG Riziotis, AR Rendina, ...
Angewandte Chemie International Edition, e202418314, 2024
32024
Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation
A Vuorinen, CR Kennedy, KA McPhie, W McCarthy, J Pettinger, ...
Communications Chemistry 8 (1), 12, 2025
12025
‘Direct-to-biology’drives optimisation of a cell-active covalent inhibitor of WRN helicase
SM Rowe, A Price, DJ Murphy, J Lin, EN Nartey, A Chaikuad, K Wong, ...
2025
ID: 204–P1. 011| Assessment of the bioorthogonality of the nitrile imine 1, 3-dipole
M Gibson, K Livingstone, J Pettinger, C Jamieson
Journal of Peptide Science 30 (S2), 82, 2024
2024
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