Targeted metabolomics for biomarker discovery WJ Griffiths, T Koal, Y Wang, M Kohl, DP Enot, HP Deigner Angewandte Chemie International Edition 49 (32), 5426-5445, 2010 | 486 | 2010 |
Role of AMACR (alpha-methylacyl-CoA racemase) and MFE-1 (peroxisomal multifunctional enzyme-1) in bile acid synthesis in mice JA Kaija, S Werner, RN Remya, MS Eija, TS Raija, JM Ilkka, JC Peter, ... Biochemical Journal 461 (1), 125-135, 2014 | 447* | 2014 |
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response M Blanc, WY Hsieh, KA Robertson, KA Kropp, T Forster, G Shui, P Lacaze, ... Immunity 38 (1), 106-118, 2013 | 428 | 2013 |
Mass spectrometry: from proteomics to metabolomics and lipidomics WJ Griffiths, Y Wang Chemical Society Reviews 38 (7), 1882-1896, 2009 | 332 | 2009 |
Electrospray and tandem mass spectrometry in biochemistry WJ Griffiths, AP Jonsson, LIU Suya, W Yuqin Biochemical Journal 355 (3), 545-561, 2001 | 303 | 2001 |
Apolipoprotein AI binds and inhibits the human antibacterial/cytotoxic peptide LL-37 Y Wang, B Agerberth, A Löthgren, A Almstedt, J Johansson Journal of Biological Chemistry 273 (50), 33115-33118, 1998 | 190 | 1998 |
Defective cholesterol metabolism in amyotrophic lateral sclerosis J Abdel-Khalik, E Yutuc, PJ Crick, JÅ Gustafsson, M Warner, G Roman, ... Journal of lipid research 58 (1), 267-278, 2017 | 161 | 2017 |
Targeted metabolomics and mass spectrometry E Dudley, M Yousef, Y Wang, WJ Griffiths Advances in protein chemistry and structural biology 80, 45-83, 2010 | 154 | 2010 |
Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? M Ogundare, S Theofilopoulos, A Lockhart, LJ Hall, E Arenas, J Sjövall, ... Journal of Biological Chemistry 285 (7), 4666-4679, 2010 | 143 | 2010 |
Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis S Theofilopoulos, Y Wang, SS Kitambi, P Sacchetti, KM Sousa, K Bodin, ... Nature chemical biology 9 (2), 126-133, 2013 | 142 | 2013 |
Analysis of oxysterols by electrospray tandem mass spectrometry WJ Griffiths, Y Wang, G Alvelius, S Liu, K Bodin, J Sjövall Journal of the American Society for Mass Spectrometry 17 (3), 341-362, 2006 | 127 | 2006 |
Liquid chromatography-mass spectrometry utilizing multi-stage fragmentation for the identification of oxysterols K Karu, M Hornshaw, G Woffendin, K Bodin, M Hamberg, G Alvelius, ... Journal of lipid research 48 (4), 976-987, 2007 | 123 | 2007 |
Effects of a disrupted blood-brain barrier on cholesterol homeostasis in the brain AA Saeed, G Genové, T Li, D Lütjohann, M Olin, N Mast, IA Pikuleva, ... Journal of Biological Chemistry 289 (34), 23712-23722, 2014 | 110 | 2014 |
Methods for oxysterol analysis: past, present and future WJ Griffiths, PJ Crick, Y Wang Biochemical pharmacology 86 (1), 3-14, 2013 | 110 | 2013 |
Cholestenoic acids regulate motor neuron survival via liver X receptors. S Theofilopoulos, WJ Griffiths, PJ Crick, S Yang, A Meljon, M Ogundare, ... The Journal of clinical investigation 124 (11), 4829-4842, 2014 | 107 | 2014 |
Quantitative charge-tags for sterol and oxysterol analysis PJ Crick, TW Bentley, J Abdel-Khalik, I Matthews, PT Clayton, AA Morris, ... Clinical chemistry 61 (2), 400-411, 2015 | 103 | 2015 |
The effect of 24S-hydroxycholesterol on cholesterol homeostasis in neurons: quantitative changes to the cortical neuron proteome Y Wang, S Muneton, J Sjövall, JN Jovanovic, WJ Griffiths Journal of proteome research 7 (4), 1606-1614, 2008 | 95 | 2008 |
Cholesterol metabolites exported from human brain L Iuliano, PJ Crick, C Zerbinati, L Tritapepe, J Abdel-Khalik, M Poirot, ... Steroids 99, 189-193, 2015 | 93 | 2015 |
New methods for analysis of oxysterols and related compounds by LC–MS WJ Griffiths, J Abdel-Khalik, PJ Crick, E Yutuc, Y Wang The Journal of steroid biochemistry and molecular biology 162, 4-26, 2016 | 88 | 2016 |
Discovering oxysterols in plasma: a window on the metabolome WJ Griffiths, M Hornshaw, G Woffendin, SF Baker, A Lockhart, ... Journal of proteome research 7 (8), 3602-3612, 2008 | 86 | 2008 |