Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor–positive breast cancer R Jeselsohn, R Yelensky, G Buchwalter, G Frampton, F Meric-Bernstam, ... Clinical cancer research 20 (7), 1757-1767, 2014 | 727 | 2014 |
ESR1 mutations—a mechanism for acquired endocrine resistance in breast cancer R Jeselsohn, G Buchwalter, C De Angelis, M Brown, R Schiff Nature reviews Clinical oncology 12 (10), 573-583, 2015 | 677 | 2015 |
Ets ternary complex transcription factors G Buchwalter, C Gross, B Wasylyk Gene 324, 1-14, 2004 | 486 | 2004 |
Allele-specific chromatin recruitment and therapeutic vulnerabilities of ESR1 activating mutations R Jeselsohn, JS Bergholz, M Pun, MI Cornwell, W Liu, A Nardone, T Xiao, ... Cancer cell 33 (2), 173-186. e5, 2018 | 273 | 2018 |
Net‐targeted mutant mice develop a vascular phenotype and up‐regulate egr‐1 A Ayadi, H Zheng, P Sobieszczuk, G Buchwalter, P Moerman, K Alitalo, ... The EMBO journal, 2001 | 156 | 2001 |
Embryonic transcription factor SOX9 drives breast cancer endocrine resistance R Jeselsohn, MI Cornwell, M Pun, G Buchwalter, M Nguyen, C Bango, ... Proceedings of the National Academy of Sciences 114 (22), E4482-E4491, 2017 | 119 | 2017 |
The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells SW Fanning, R Jeselsohn, V Dharmarajan, CG Mayne, M Karimi, ... Elife 7, e37161, 2018 | 99 | 2018 |
Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter G Fiucci, S Beaucourt, D Duflaut, A Lespagnol, P Stumptner-Cuvelette, ... Proceedings of the National Academy of Sciences 101 (10), 3510-3515, 2004 | 96 | 2004 |
ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor Z Mounir, JM Korn, T Westerling, F Lin, CA Kirby, M Schirle, G McAllister, ... Elife 5, e13964, 2016 | 88 | 2016 |
Regulation of MCP-1 chemokine transcription by p53 K Hacke, B Rincon-Orozco, G Buchwalter, SY Siehler, B Wasylyk, ... Molecular cancer 9, 1-12, 2010 | 87 | 2010 |
TMPRSS2: ERG blocks neuroendocrine and luminal cell differentiation to maintain prostate cancer proliferation Z Mounir, F Lin, VG Lin, JM Korn, Y Yu, R Valdez, OH Aina, G Buchwalter, ... Oncogene 34 (29), 3815-3825, 2015 | 75 | 2015 |
PDEF promotes luminal differentiation and acts as a survival factor for ER-positive breast cancer cells G Buchwalter, MM Hickey, A Cromer, LM Selfors, RN Gunawardane, ... Cancer cell 23 (6), 753-767, 2013 | 72 | 2013 |
The ternary complex factor Net regulates cell migration through inhibition of PAI-1 expression G Buchwalter, C Gross, B Wasylyk Molecular and cellular biology 25 (24), 10853-10862, 2005 | 70 | 2005 |
Unraveling the clinicopathological features driving the emergence of ESR1 mutations in metastatic breast cancer Y Kuang, B Siddiqui, J Hu, M Pun, MI Cornwell, G Buchwalter, ... NPJ breast Cancer 4 (1), 22, 2018 | 52 | 2018 |
Loss of net as repressor leads to constitutive increased c-fos transcription in cervical cancer cells J Van Riggelen, G Buchwalter, U Soto, JDC Arce, H Zur Hausen, ... Journal of Biological Chemistry 280 (5), 3286-3294, 2005 | 35 | 2005 |
The ternary complex factor net is downregulated by hypoxia and regulates hypoxia-responsive genes C Gross, G Buchwalter, H Dubois-Pot, E Cler, H Zheng, B Wasylyk Molecular and Cellular Biology 27 (11), 4133-4141, 2007 | 30 | 2007 |
The tumor suppressor p53 inhibits Net, an effector of Ras/extracellular signal-regulated kinase signaling K Nakade, H Zheng, G Ganguli, G Buchwalter, C Gross, B Wasylyk Molecular and cellular biology 24 (3), 1132-1142, 2004 | 26 | 2004 |
Digital quantification of gene expression in sequential breast cancer biopsies reveals activation of an immune response RM Jeselsohn, L Werner, MM Regan, A Fatima, L Gilmore, LC Collins, ... PLoS One 8 (5), e64225, 2013 | 18 | 2013 |
Emergence of constitutively active estrogen receptor mutations in advanced estrogen receptor positive breast cancer RM Jeselsohn, R Yelensky, G Buchwalter, G Frampton, F Meric-Bernstam, ... CANCER RESEARCH 73, 2013 | 4 | 2013 |
Abstract P3-05-09: Exploring bazedoxifene and palbociclib as potential therapeutic strategies for overcoming ESR1-mediated endocrine resistance M Nguyen, G Buchwalter, F Luo, L Garraway, M Brown, R Jeselsohn Cancer Research 76 (4_Supplement), P3-05-09-P3-05-09, 2016 | 2 | 2016 |