The mutational landscape of lethal castration-resistant prostate cancer CS Grasso, YM Wu, DR Robinson, X Cao, SM Dhanasekaran, AP Khan, ... Nature 487 (7406), 239-243, 2012 | 2838 | 2012 |
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer S Varambally, Q Cao, RS Mani, S Shankar, X Wang, B Ateeq, B Laxman, ... science 322 (5908), 1695-1699, 2008 | 1364 | 2008 |
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression JR Prensner, MK Iyer, OA Balbin, SM Dhanasekaran, Q Cao, JC Brenner, ... Nature biotechnology 29 (8), 742-749, 2011 | 1168 | 2011 |
An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression J Yu, J Yu, RS Mani, Q Cao, CJ Brenner, X Cao, X Wang, L Wu, J Li, M Hu, ... Cancer cell 17 (5), 443-454, 2010 | 1019 | 2010 |
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974 J Liu, S Pan, MH Hsieh, N Ng, F Sun, T Wang, S Kasibhatla, AG Schuller, ... Proceedings of the National Academy of Sciences 110 (50), 20224-20229, 2013 | 886 | 2013 |
Dual roles of PARP-1 promote cancer growth and progression MJ Schiewer, JF Goodwin, S Han, JC Brenner, MA Augello, JL Dean, ... Cancer discovery 2 (12), 1134-1149, 2012 | 486 | 2012 |
Mechanistic rationale for inhibition of poly (ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer JC Brenner, B Ateeq, Y Li, AK Yocum, Q Cao, IA Asangani, S Patel, ... Cancer cell 19 (5), 664-678, 2011 | 479 | 2011 |
Chimeric transcript discovery by paired-end transcriptome sequencing CA Maher, N Palanisamy, JC Brenner, X Cao, S Kalyana-Sundaram, ... Proceedings of the National Academy of Sciences 106 (30), 12353-12358, 2009 | 427 | 2009 |
Antibody-based detection of ERG rearrangement-positive prostate cancer K Park, SA Tomlins, KM Mudaliar, YL Chiu, R Esgueva, R Mehra, ... Neoplasia 12 (7), 590-IN21, 2010 | 415 | 2010 |
Genotyping of 73 UM‐SCC head and neck squamous cell carcinoma cell lines JC Brenner, MP Graham, B Kumar, LM Saunders, R Kupfer, RH Lyons, ... Head & Neck: Journal for the Sciences and Specialties of the Head and Neck …, 2010 | 346 | 2010 |
PARP-1 inhibition as a targeted strategy to treat Ewing's sarcoma JC Brenner, FY Feng, S Han, S Patel, SV Goyal, LM Bou-Maroun, M Liu, ... Cancer research 72 (7), 1608-1613, 2012 | 327 | 2012 |
Coordinated regulation of polycomb group complexes through microRNAs in cancer Q Cao, RS Mani, B Ateeq, SM Dhanasekaran, IA Asangani, JR Prensner, ... Cancer cell 20 (2), 187-199, 2011 | 237 | 2011 |
A novel BH3 mimetic reveals a mitogen-activated protein kinase–dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species M Verhaegen, JA Bauer, C Martín de la Vega, G Wang, KG Wolter, ... Cancer research 66 (23), 11348-11359, 2006 | 173 | 2006 |
Prognostic value of tumor-infiltrating lymphocytes in head and neck squamous cell carcinoma ME Spector, E Bellile, L Amlani, K Zarins, J Smith, JC Brenner, L Rozek, ... JAMA otolaryngology–head & neck surgery 145 (11), 1012-1019, 2019 | 155 | 2019 |
HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING X Luo, CR Donnelly, W Gong, BR Heath, Y Hao, LA Donnelly, T Moghbeli, ... The Journal of clinical investigation 130 (4), 1635-1652, 2020 | 146 | 2020 |
Molecular pathways: targeting ETS gene fusions in cancer FY Feng, JC Brenner, M Hussain, AM Chinnaiyan Clinical Cancer Research 20 (17), 4442-4448, 2014 | 86 | 2014 |
Correlation of Crtc1/3-Maml2 fusion status, grade and survival in mucoepidermoid carcinoma AC Birkeland, SK Foltin, NL Michmerhuizen, RC Hoesli, AJ Rosko, S Byrd, ... Oral oncology 68, 5-8, 2017 | 85 | 2017 |
Early HPV ctDNA kinetics and imaging biomarkers predict therapeutic response in p16+ oropharyngeal squamous cell carcinoma Y Cao, CT Haring, C Brummel, C Bhambhani, M Aryal, C Lee, M Heft Neal, ... Clinical Cancer Research 28 (2), 350-359, 2022 | 75 | 2022 |
Proportion of CD4 and CD8 tumor infiltrating lymphocytes predicts survival in persistent/recurrent laryngeal squamous cell carcinoma R Hoesli, AC Birkeland, AJ Rosko, M Issa, KL Chow, NL Michmerhuizen, ... Oral oncology 77, 83-89, 2018 | 73 | 2018 |
TMPRSS2–ERG-mediated feed-forward regulation of wild-type ERG in human prostate cancers RS Mani, MK Iyer, Q Cao, JC Brenner, L Wang, A Ghosh, X Cao, ... Cancer research 71 (16), 5387-5392, 2011 | 68 | 2011 |