Klaus Okkenhaug

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Bart VanhaesebroeckUCL Cancer Institute, University College London, London UKZweryfikowany adres z ucl.ac.uk
Martin TurnerThe Babraham Institute, Cambridge, CB22 3AT, UK.Zweryfikowany adres z babraham.ac.uk
Rahul RoychoudhuriUniversity of CambridgeZweryfikowany adres z cam.ac.uk
Dan PattonMozart TherapeuticsZweryfikowany adres z mail.ubc.ca
Fabien GarconThe Babraham InstituteZweryfikowany adres z babraham.ac.uk
Oliver A GardenDean of School of Veterinary Medicine, Louisiana State UniversityZweryfikowany adres z lsu.edu
Federica Marelli-BergBHF Professor of Cardiovascular Immunology, Queen Mary University of LondonZweryfikowany adres z qmul.ac.uk
Alison CondliffeProfessor of Respiratory Medicine, University of SheffieldZweryfikowany adres z sheffield.ac.uk
Rottapel RScientist, Princess Margaret Cancer CentreZweryfikowany adres z uhnresearch.ca
Anita ChandraUniversity of CambridgeZweryfikowany adres z cam.ac.uk
Phillip HawkinsGroup Leader, Babraham InstituteZweryfikowany adres z babraham.ac.uk
len stephensThe Babraham Institute, Cambridge, UKZweryfikowany adres z babraham.ac.uk
David FinlayTrinity College DublinZweryfikowany adres z tcd.ie
D CantrellProfessor of Immunology, Dundee UniversityZweryfikowany adres z dundee.ac.uk
Linda V. SinclairUniversity of DundeeZweryfikowany adres z dundee.ac.uk
Thomas RueckleBioMed X InstituteZweryfikowany adres z bio.mx
Emilio HirschUniversity of TorinoZweryfikowany adres z unito.it
Ee Lyn LimSenior Scientist (Postdoctoral Researcher), BioMed X InstituteZweryfikowany adres z bio.mx
Anton EnrightProfessor of RNA Biology and Genomics, Pathology Dept., University of CambridgeZweryfikowany adres z cam.ac.uk
Gordon DouganUniversity of CambridgeZweryfikowany adres z cam.ac.uk

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Klaus Okkenhaug

Division of Immunology, Department of Pathology, University of Cambridge

Zweryfikowany adres z cam.ac.uk - Strona główna

Immunology Cell Signalling PI3K Cancer Immunotherapy Primary Immunodeficiency


Tytuł Sortuj wg cytatów Sortuj wg roku Sortuj wg tytułu	Cytowane przez Cytowane przez	Rok
Requirement of bic/microRNA-155 for normal immune function A Rodriguez, E Vigorito, S Clare, MV Warren, P Couttet, DR Soond, ... Science 316 (5824), 608, 2007	2412	2007
Cellular function of phosphoinositide 3-kinases: implications for development, immunity, homeostasis, and cancer R Katso, K Okkenhaug, K Ahmadi, S White, J Timms, MD Waterfield Annual review of cell and developmental biology 17 (1), 615-675, 2001	1708	2001
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span C Selman, J Tullet, D Wieser, E Irvine, SJ Lingard, AI Choudhury, M Claret, ... Science 326 (5949), 140, 2009	1297	2009
Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice K Okkenhaug, A Bilancio, G Farjot, H Priddle, S Sancho, E Peskett, ... Science 297 (5583), 1031, 2002	1200	2002
PI3K in lymphocyte development, differentiation and activation K Okkenhaug, B Vanhaesebroeck Nature Reviews Immunology 3 (4), 317-330, 2003	1023	2003
Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage I Angulo, O Vadas, F Garçon, E Banham-Hall, V Plagnol, TR Leahy, ... Science 342 (6169), 866-871, 2013	680	2013
PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells DK Finlay, E Rosenzweig, LV Sinclair, C Feijoo-Carnero, JL Hukelmann, ... The Journal of Experimental Medicine 209 (13), 2441-2453, 2012	663	2012
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice C Selman, S Lingard, AI Choudhury, RL Batterham, M Claret, M Clements, ... The FASEB Journal 22 (3), 807-818, 2008	634	2008
Ionic immune suppression within the tumour microenvironment limits T cell effector function R Eil, SK Vodnala, D Clever, CA Klebanoff, M Sukumar, JH Pan, ... Nature 537 (7621), 539-543, 2016	620	2016
Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: a large patient cohort study TI Coulter, A Chandra, CM Bacon, J Babar, J Curtis, N Screaton, ... Journal of Allergy and Clinical Immunology 139 (2), 597-606. e4, 2017	598	2017
Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation LC Foukas, M Claret, W Pearce, K Okkenhaug, S Meek, E Peskett, ... Nature 441 (7091), 366-370, 2006	575	2006
Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer K Ali, DR Soond, R Piñeiro, T Hagemann, W Pearce, EL Lim, H Bouabe, ... Nature 510 (7505), 407-411, 2014	558	2014
Essential role for the p110δ phosphoinositide 3-kinase in the allergic response K Ali, A Bilancio, M Thomas, W Pearce, AM Gilfillan, C Tkaczyk, N Kuehn, ... Nature 431 (7011), 1007-1011, 2004	510	2004
Signaling by the Phosphoinositide 3-Kinase Family in Immune Cells K Okkenhaug Annual review of immunology 31 (1), 2013	507	2013
Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells S Kohlhaas, OA Garden, C Scudamore, M Turner, K Okkenhaug, ... The Journal of Immunology 182 (5), 2578-2582, 2009	475	2009
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking LV Sinclair, D Finlay, C Feijoo, GH Cornish, A Gray, A Ager, K Okkenhaug, ... Nature immunology 9 (5), 513-521, 2008	471	2008
The p110β isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110γ J Guillermet-Guibert, K Bjorklof, A Salpekar, C Gonella, F Ramadani, ... Proceedings of the National Academy of Sciences 105 (24), 8292-8297, 2008	445	2008
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils AM Condliffe, K Davidson, KE Anderson, CD Ellson, T Crabbe, ... Blood 106 (4), 1432-1440, 2005	382	2005
Cutting edge: the phosphoinositide 3-kinase p110δ is critical for the function of CD4+ CD25+ Foxp3+ regulatory T cells DT Patton, OA Garden, WP Pearce, LE Clough, CR Monk, E Leung, ... The Journal of Immunology 177 (10), 6598-6602, 2006	381	2006
PI3K inhibitors are finally coming of age B Vanhaesebroeck, MWD Perry, JR Brown, F André, K Okkenhaug Nature reviews Drug discovery 20 (10), 741-769, 2021	344	2021

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