AKT1 and AKT2 isoforms play distinct roles during breast cancer progression through the regulation of specific downstream proteins M Riggio, MC Perrone, ML Polo, MJ Rodriguez, M May, M Abba, C Lanari, ... Scientific reports 7 (1), 44244, 2017 | 143 | 2017 |
Collagen-IV and laminin-1 regulate estrogen receptor α expression and function in mouse mammary epithelial cells V Novaro, CD Roskelley, MJ Bissell Journal of cell science 116 (14), 2975-2986, 2003 | 128 | 2003 |
Carcinoma‐associated fibroblasts activate progesterone receptors and induce hormone independent mammary tumor growth: a role for the FGF‐2/FGFR‐2 axis S Giulianelli, JP Cerliani, CA Lamb, VT Fabris, MC Bottino, MA Gorostiaga, ... International journal of cancer 123 (11), 2518-2531, 2008 | 120 | 2008 |
Nitric oxide synthase regulation during embryonic implantation V Novaro, E Gonzalez, A Jawerbaum, V Rettori, G Canteros, MF Gimeno Reproduction, fertility and development 9 (5), 557-564, 1997 | 78 | 1997 |
Regulation of metalloproteinases by nitric oxide in human trophoblast cells in culture V Novaro, A Colman-Lerner, FV Ortega, A Jawerbaum, D Paz, FL Nostro, ... Reproduction, Fertility and Development 13 (6), 411-420, 2001 | 74 | 2001 |
Interaction between uterine PGE and PGF2α production and the nitridergic system during embryonic implantation in the rat V Novaro, V Rettori, ET Gonzalez, A Jawerbaum, A Faletti, G Canteros, ... Prostaglandins 51 (6), 363-376, 1996 | 66 | 1996 |
PI3K/AKT pathway regulates phosphorylation of steroid receptors, hormone independence and tumor differentiation in breast cancer M Riggio, ML Polo, M Blaustein, A Colman-Lerner, I Lüthy, C Lanari, ... Carcinogenesis 33 (3), 509-518, 2012 | 64 | 2012 |
FGF2 induces breast cancer growth through ligand‐independent activation and recruitment of ERα and PRBΔ4 isoform to MYC regulatory sequences S Giulianelli, M Riggio, T Guillardoy, C Pérez Piñero, MA Gorostiaga, ... International journal of cancer 145 (7), 1874-1888, 2019 | 62 | 2019 |
Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters V Wargon, M Riggio, S Giulianelli, GR Sequeira, P Rojas, M May, ML Polo, ... International journal of cancer 136 (11), 2680-2692, 2015 | 59 | 2015 |
Nitric oxide induces gelatinase A (matrix metalloproteinase 2) during rat embryo implantation V Novaro, C Pustovrh, A Colman-Lerner, D Radisky, FL Nostro, D Paz, ... Fertility and Sterility 78 (6), 1278-1287, 2002 | 52 | 2002 |
Reversal of antiprogestin resistance and progesterone receptor isoform ratio in acquired resistant mammary carcinomas V Wargon, LA Helguero, J Bolado, P Rojas, V Novaro, A Molinolo, ... Breast cancer research and treatment 116, 449-460, 2009 | 49 | 2009 |
Responsiveness to PI3K and MEK inhibitors in breast cancer. Use of a 3D culture system to study pathways related to hormone independence in mice ML Polo, MV Arnoni, M Riggio, V Wargon, C Lanari, V Novaro PLoS One 5 (5), e10786, 2010 | 39 | 2010 |
Identification of a somatic mutation in the RHEB gene through high depth and ultra-high depth next generation sequencing in a patient with Hemimegalencephaly and drug resistant … V Salinas, P Vega, MV Piccirilli, C Chicco, C Ciraolo, S Christiansen, ... European Journal of Medical Genetics 62 (11), 103571, 2019 | 33 | 2019 |
Activation of PI3K/Akt/mTOR signaling in the tumor stroma drives endocrine therapy-dependent breast tumor regression ML Polo, M Riggio, M May, MJ Rodríguez, MC Perrone, M Stallings-Mann, ... Oncotarget 6 (26), 22081, 2015 | 33 | 2015 |
Glucose metabolism, triglyceride and glycogen levels, as well as eicosanoid production in isolated uterine strips and in embryos in a rat model of non-insulin-dependent … A Jawerbaum, ET Gonzalez, V Novaro, AL Gimeno, J RosellóCatafau, ... Prostaglandins 47 (2), 81-96, 1994 | 32 | 1994 |
Malignant mammary cells acquire independence from extracellular context for regulation of estrogen receptor α V Novaro, DC Radisky, NER Castro, A Weisz, MJ Bissell Clinical cancer research 10 (1), 402s-409s, 2004 | 30 | 2004 |
Enhanced antitumor immunity via endocrine therapy prevents mammary tumor relapse and increases immune checkpoint blockade sensitivity GR Sequeira, A Sahores, T Dalotto-Moreno, RM Perrotta, G Pataccini, ... Cancer research 81 (5), 1375-1387, 2021 | 29 | 2021 |
Beneficial effects of mifepristone treatment in patients with breast cancer selected by the progesterone receptor isoform ratio: results from the MIPRA trial A Elía, L Saldain, SI Vanzulli, LA Helguero, CA Lamb, V Fabris, ... Clinical Cancer Research 29 (5), 866-877, 2023 | 26 | 2023 |
Increased prostaglandin E generation and enhanced nitric oxide synthase activity in the non-insulin-dependent diabetic embryo during organogenesis A Jawerbaum, ET Gonzalez, V Novaro, A Faletti, D Sinner, MAF Gimeno Reproduction, fertility and development 10 (2), 191-196, 1998 | 25 | 1998 |
Eicosanoid production, metabolism and contractile activity in the isolated uterus from non-insulin-dependent diabetic rats during late pregnancy A Jawerbaum, JR Catafau, ET Gonzalez, V Novaro, G Gómez, E Gelpi, ... Prostaglandins 51 (5), 307-320, 1996 | 25 | 1996 |