| Antimuscarinic drugs for overactive bladder and their potential effects on cognitive function in older patients GG Kay, MB Abou‐Donia, WS Messer Jr, DG Murphy, JW Tsao, ... Journal of the American Geriatrics Society 53 (12), 2195-2201, 2005 | 246 | 2005 |
| A simple spatial alternation task for assessing memory function in zebrafish FE Williams, D White, WS Messer Jr Behavioural processes 58 (3), 125-132, 2002 | 230 | 2002 |
| Pharmacology: principles and practice M Hacker, WS Messer, KA Bachmann Academic Press, 2009 | 175 | 2009 |
| Evidence for a preferential involvement of M1 muscarinic receptors in representational memory WS Messer Jr, M Bohnett, J Stibbe Neuroscience letters 116 (1-2), 184-189, 1990 | 116 | 1990 |
| Synthesis and biological characterization of 1, 4, 5, 6-tetrahydropyrimidine and 2-amino-3, 4, 5, 6-tetrahydropyridine derivatives as selective m1 agonists WS Messer, YF Abuh, Y Liu, S Periyasamy, DO Ngur, MAN Edgar, ... Journal of medicinal chemistry 40 (8), 1230-1246, 1997 | 114 | 1997 |
| Muscarinic agonists PG Dunbar, GJ Durant, WP Hoss, WS Messer Jr US Patent 5,403,845, 1995 | 74 | 1995 |
| Bivalent ligands for G protein-coupled receptors WS Messer Jr Current pharmaceutical design 10 (17), 2015-2020, 2004 | 72 | 2004 |
| Design, synthesis, and neurochemical evaluation of 5-(3-alkyl-1, 2, 4-oxadiazol-5-yl)-1, 4, 5, 6-tetrahydropyrimidines as M1 muscarinic receptor agonists PG Dunbar, GJ Durant, Z Fang, YF Abuh, AA El-Assadi, DO Ngur, ... Journal of medicinal chemistry 36 (7), 842-847, 1993 | 72 | 1993 |
| Biochemical and behavioral evidence for muscarinic autoreceptors in the CNS W Hoss, WS Messer Jr, FJ Monsma Jr, MD Miller, BR Ellerbrock, ... Brain research 517 (1-2), 195-201, 1990 | 69 | 1990 |
| Cholinergic agonists and the treatment of Alzheimer's disease WS MesserJr Current Topics in Medicinal Chemistry 2 (4), 353-358, 2002 | 66 | 2002 |
| Muscarinic agonists WS Messer Jr, B Ojo US Patent 5,726,179, 1998 | 66 | 1998 |
| Muscarinic agonists PG Dunbar, GJ Durant, WP Hoss, WS Messer Jr US Patent 5,175,166, 1992 | 65 | 1992 |
| Selectivity of pirenzepine in the central nervous system. II. Differential effects of pirenzepine and scopolamine on performance of a representational memory task WS Messer Jr, GJ Thomas, W Hoss Brain research 407 (1), 37-45, 1987 | 61 | 1987 |
| The selective M1 muscarinic cholinergic agonist CDD-0102A enhances working memory and cognitive flexibility ME Ragozzino, S Artis, A Singh, TM Twose, JE Beck, WS Messer Jr The Journal of Pharmacology and Experimental Therapeutics 340 (3), 588-594, 2012 | 60 | 2012 |
| Design, synthesis, and biological characterization of bivalent 1-methyl-1, 2, 5, 6-tetrahydropyridyl-1, 2, 5-thiadiazole derivatives as selective muscarinic agonists WG Rajeswaran, Y Cao, XP Huang, ME Wroblewski, T Colclough, S Lee, ... Journal of medicinal chemistry 44 (26), 4563-4576, 2001 | 60 | 2001 |
| Muscarinic receptor agonists WS Messer, Y Cao US Patent 6,602,891, 2003 | 56 | 2003 |
| Roles of threonine 192 and asparagine 382 in agonist and antagonist interactions with M1 muscarinic receptors XP Huang, PI Nagy, FE Williams, SM Peseckis, WS Messer Jr British journal of pharmacology 126 (3), 735-745, 1999 | 56 | 1999 |
| The utility of muscarinic agonists in the treatment of Alzheimer’s disease WS Messer Journal of Molecular Neuroscience 19, 187-193, 2002 | 49 | 2002 |
| Theoretical studies of the tautomeric equilibria for five-member N-heterocycles in the gas phase and in solution PI Nagy, FR Tejada, WS Messer The Journal of Physical Chemistry B 109 (47), 22588-22602, 2005 | 48 | 2005 |
| Internal standard method for the measurement of choline and acetylcholine by capillary electrophoresis with electrochemical detection DD Wise, TV Barkhimer, PA Brault, JR Kirchhoff, WS Messer Jr, ... Journal of Chromatography B 775 (1), 49-56, 2002 | 43 | 2002 |
