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Michael Hughes
Michael Hughes
PhD in Gene Therapy
Zweryfikowany adres z ucl.ac.uk
Tytuł
Cytowane przez
Cytowane przez
Rok
Epilepsy gene therapy using an engineered potassium channel
A Snowball, E Chabrol, RC Wykes, T Shekh-Ahmad, JH Cornford, A Lieb, ...
Journal of neuroscience 39 (16), 3159-3169, 2019
1222019
AAV9 intracerebroventricular gene therapy improves lifespan, locomotor function and pathology in a mouse model of Niemann–Pick type C1 disease
MP Hughes, DA Smith, L Morris, C Fletcher, A Colaco, M Huebecker, ...
Human Molecular Genetics 27 (17), 3079-3098, 2018
752018
Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer
J Baruteau, DP Perocheau, J Hanley, M Lorvellec, E Rocha-Ferreira, ...
Nature Communications 9 (1), 3505, 2018
472018
Systemic AAV9 gene therapy using the synapsin I promoter rescues a mouse model of neuronopathic Gaucher disease but with limited cross-correction potential to astrocytes
G Massaro, MP Hughes, SM Whaler, KL Wallom, DA Priestman, FM Platt, ...
Human molecular genetics 29 (12), 1933-1949, 2020
382020
Immediate remote ischemic postconditioning reduces brain nitrotyrosine formation in a piglet asphyxia model
E Rocha-Ferreira, B Rudge, MP Hughes, AA Rahim, M Hristova, ...
Oxidative medicine and cellular longevity 2016 (1), 5763743, 2016
342016
Neonatal brain-directed gene therapy rescues a mouse model of neurodegenerative CLN6 Batten disease
SM kleine Holthaus, S Herranz-Martin, G Massaro, M Aristorena, J Hoke, ...
Human molecular genetics 28 (23), 3867-3879, 2019
292019
Perinatal systemic gene delivery using adeno-associated viral vectors
R Karda, SMK Buckley, CN Mattar, J Ng, G Massaro, MP Hughes, ...
Frontiers in Molecular Neuroscience 7, 89, 2014
252014
Changes in internet suicide search volumes following celebrity suicides
SN Ortiz, LN Forrest, TJ Fisher, M Hughes, AR Smith
Cyberpsychology, Behavior, and Social Networking 22 (6), 373-380, 2019
162019
Delay to surgery in acute perforated and ischaemic gastrointestinal pathology: a systematic review
V Murray, JR Burke, M Hughes, C Schofield, A Young
BJS open 5 (5), zrab072, 2021
142021
A GLP1 receptor agonist diabetes drug ameliorates neurodegeneration in a mouse model of infantile neurometabolic disease
L Poupon-Bejuit, MP Hughes, W Liu, A Geard, N Faour-Slika, S Whaler, ...
Scientific Reports 12 (1), 13825, 2022
122022
A Novel Small NPC1 Promoter Enhances AAV-Mediated Gene Therapy in Mouse Models of Niemann–Pick Type C1 Disease
MP Hughes, HR Nelvagal, O Coombe-Tennant, D Smith, C Smith, ...
Cells 12 (12), 1619, 2023
102023
Quality of life after severe acute pancreatitis: systematic review
A Giorga, M Hughes, S Parker, A Smith, A Young
BJS open 7 (4), zrad067, 2023
62023
Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors
R Karda, AA Rahim, AMS Wong, N Suff, JA Diaz, DP Perocheau, M Tijani, ...
Scientific reports 10 (1), 2121, 2020
62020
Dysregulated Wnt and NFAT signaling in a Parkinson’s disease LRRK2 G2019S knock-in model
A Wetzel, SH Lei, T Liu, MP Hughes, Y Peng, T McKay, SN Waddington, ...
Scientific reports 14 (1), 12393, 2024
52024
Dipolar Bose-Hubbard model in finite-size real-space cylindrical lattices
M Hughes, D Jaksch
Physical Review A 105 (5), 053301, 2022
52022
305. Generation of light-producing, somatic-transgenic mice using lentivirus and adeno-associated virus vectors
R Karda, DP Perocheau, SMK Buckley, JMKM Delhove, M Hughes, ...
Molecular Therapy 24, S123, 2016
22016
Embedding a novel screening programme for sexually transmitted infections (chlamydia and gonorrhoea) within an ambulatory emergency surgical assessment unit: an observational …
D Ganesh, C Mahon, S Jones, H Please, M Hughes, A Peckham-Cooper
Sexually Transmitted Infections 100 (6), 381-383, 2024
12024
Generation of light-producing somatic-transgenic mice using adeno-associated virus vector
R Karda, AA Rahim, N Suff, JA Diaz, DP Perocheau, NP Martin, ...
Molecular Therapy 26 (5), 40-40, 2018
12018
Development of gene therapy for Niemann-Pick Type C disease
M Hughes, D Smith, L Morris, J Tordo, N Palomar-Martin, E Henckaerts, ...
Human Gene Therapy 27 (7), A14-A14, 2016
12016
Gene therapy methods for treatment of diabetes
M Hughes, S Dhall, H Wu, VA Fonseca
US Patent App. 18/715,015, 2025
2025
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