| A SARS-CoV-2 protein interaction map reveals targets for drug repurposing DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ... Nature 583 (7816), 459-468, 2020 | 4774 | 2020 |
| Microglia development and function D Nayak, TL Roth, DB McGavern Annual review of immunology 32 (1), 367-402, 2014 | 1276 | 2014 |
| Inflammation and neuroprotection in traumatic brain injury KN Corps, TL Roth, DB McGavern JAMA neurology 72 (3), 355-362, 2015 | 911 | 2015 |
| Reprogramming human T cell function and specificity with non-viral genome targeting TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ... Nature 559 (7714), 405-409, 2018 | 873 | 2018 |
| Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 697 | 2020 |
| Transcranial amelioration of inflammation and cell death after brain injury TL Roth, D Nayak, T Atanasijevic, AP Koretsky, LL Latour, DB McGavern Nature 505 (7482), 223-228, 2014 | 619 | 2014 |
| Genome-wide CRISPR screens in primary human T cells reveal key regulators of immune function E Shifrut, J Carnevale, V Tobin, TL Roth, JM Woo, CT Bui, PJ Li, ... Cell 175 (7), 1958-1971. e15, 2018 | 515 | 2018 |
| Discovery of stimulation-responsive immune enhancers with CRISPR activation DR Simeonov, BG Gowen, M Boontanrart, TL Roth, JD Gagnon, ... Nature 549 (7670), 111-115, 2017 | 316 | 2017 |
| Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency DN Nguyen, TL Roth, PJ Li, PA Chen, R Apathy, MR Mamedov, LT Vo, ... Nature biotechnology 38 (1), 44-49, 2020 | 287 | 2020 |
| CRISPR screen in regulatory T cells reveals modulators of Foxp3 JT Cortez, E Montauti, E Shifrut, J Gatchalian, Y Zhang, O Shaked, Y Xu, ... Nature 582 (7812), 416-420, 2020 | 204 | 2020 |
| Pooled knockin targeting for genome engineering of cellular immunotherapies TL Roth, PJ Li, F Blaeschke, JF Nies, R Apathy, C Mowery, R Yu, ... Cell 181 (3), 728-744. e21, 2020 | 190 | 2020 |
| Orthotopic replacement of T-cell receptor α-and β-chains with preservation of near-physiological T-cell function K Schober, TR Müller, F Gökmen, S Grassmann, M Effenberger, ... Nature biomedical engineering 3 (12), 974-984, 2019 | 181 | 2019 |
| High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails BR Shy, VS Vykunta, A Ha, A Talbot, TL Roth, DN Nguyen, WG Pfeifer, ... Nature biotechnology 41 (4), 521-531, 2023 | 157 | 2023 |
| Large dataset enables prediction of repair after CRISPR–Cas9 editing in primary T cells RT Leenay, A Aghazadeh, J Hiatt, D Tse, TL Roth, R Apathy, E Shifrut, ... Nature biotechnology 37 (9), 1034-1037, 2019 | 128 | 2019 |
| RASA2 ablation in T cells boosts antigen sensitivity and long-term function J Carnevale, E Shifrut, N Kale, WA Nyberg, F Blaeschke, YY Chen, Z Li, ... Nature 609 (7925), 174-182, 2022 | 124 | 2022 |
| CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions JF Hultquist, J Hiatt, K Schumann, MJ McGregor, TL Roth, P Haas, ... Nature protocols 14 (1), 1-27, 2019 | 124 | 2019 |
| The CD28-transmembrane domain mediates chimeric antigen receptor heterodimerization with CD28 YD Muller, DP Nguyen, LMR Ferreira, P Ho, C Raffin, RVB Valencia, ... Frontiers in immunology 12, 639818, 2021 | 114 | 2021 |
| Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1 L Milenkovic, LE Weiss, J Yoon, TL Roth, YRS Su, SJ Sahl, MP Scott, ... Proceedings of the National Academy of Sciences 112 (27), 8320-8325, 2015 | 108 | 2015 |
| XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment Y Lee, D Bogdanoff, Y Wang, GC Hartoularos, JM Woo, CT Mowery, ... Science advances 7 (17), eabg4755, 2021 | 104 | 2021 |
| Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node Y Zhang, TL Roth, EE Gray, H Chen, LB Rodda, Y Liang, P Ventura, ... Elife 5, e18156, 2016 | 82 | 2016 |
Alexander MarsonDirector of Gladstone-UCSF Institute of Genomic Immunology, Professor, Department of MedicineZweryfikowany adres z ucsf.edu
