GDE2 promotes neurogenesis by glycosylphosphatidylinositol-anchor cleavage of RECK S Park, C Lee, P Sabharwal, M Zhang, CLF Meyers, S Sockanathan Science 339 (6117), 324-328, 2013 | 134 | 2013 |
Physiologically based pharmacokinetic modelling to inform development of intramuscular long-acting nanoformulations for HIV RKR Rajoli, DJ Back, S Rannard, CL Freel Meyers, C Flexner, A Owen, ... Clinical pharmacokinetics 54, 639-650, 2015 | 118 | 2015 |
Thin‐layer chromatography CLF Meyers, DJ Meyers Current protocols in nucleic acid chemistry 34 (1), A. 3D. 1-A. 3D. 13, 2008 | 104 | 2008 |
Antibiotic glycosyltransferases: antibiotic maturation and prospects for reprogramming C Walsh, CL Freel Meyers, HC Losey Journal of medicinal chemistry 46 (16), 3425-3436, 2003 | 94 | 2003 |
1-Deoxy-D-xylulose 5-phosphate synthase catalyzes a novel random sequential mechanism LA Brammer, JM Smith, H Wade, CF Meyers Journal of Biological Chemistry 286 (42), 36522-36531, 2011 | 85 | 2011 |
Pharmacological activation of myosin II paralogs to correct cell mechanics defects A Surcel, WP Ng, H West-Foyle, Q Zhu, Y Ren, LB Avery, AK Krenc, ... Proceedings of the National Academy of Sciences 112 (5), 1428-1433, 2015 | 76 | 2015 |
Observation of Thiamin-Bound Intermediates and Microscopic Rate Constants for Their Interconversion on 1-Deoxy-d-xylulose 5-Phosphate Synthase: 600-Fold Rate … H Patel, NS Nemeria, LA Brammer, CL Freel Meyers, F Jordan Journal of the American Chemical Society 134 (44), 18374-18379, 2012 | 76 | 2012 |
Characterization of NovP and NovN: completion of novobiocin biosynthesis by sequential tailoring of the noviosyl ring CLF Meyers, M Oberthür, H Xu, L Heide, D Kahne, CT Walsh Angewandte Chemie-International Edition 43 (1), 67-70, 2004 | 73 | 2004 |
Initial characterization of novobiocic acid noviosyl transferase activity of NovM in biosynthesis of the antibiotic novobiocin CL Freel Meyers, M Oberthür, JW Anderson, D Kahne, CT Walsh Biochemistry 42 (14), 4179-4189, 2003 | 63 | 2003 |
Activation mechanisms of nucleoside phosphoramidate prodrugs CL Freel Meyers, RF Borch Journal of medicinal chemistry 43 (22), 4319-4327, 2000 | 63 | 2000 |
Selective inhibition of E. coli 1-deoxy-D-xylulose-5-phosphate synthase by acetylphosphonates JM Smith, RJ Vierling, CF Meyers MedChemComm 3 (1), 65-67, 2012 | 61 | 2012 |
Revealing Substrate Promiscuity of 1-Deoxy-d-xylulose 5-Phosphate Synthase LA Brammer, CF Meyers Organic letters 11 (20), 4748-4751, 2009 | 61 | 2009 |
Synthesis and biological activity of novel 5-fluoro-2 ‘-deoxyuridine phosphoramidate prodrugs CL Freel Meyers, L Hong, C Joswig, RF Borch Journal of medicinal chemistry 43 (22), 4313-4318, 2000 | 58 | 2000 |
Identification of an Atg8-Atg3 protein–protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum … AUP Hain, D Bartee, NG Sanders, AS Miller, DJ Sullivan, J Levitskaya, ... Journal of medicinal chemistry 57 (11), 4521-4531, 2014 | 57 | 2014 |
2C-Methyl-d-erythritol 4-Phosphate Enhances and Sustains Cyclodiphosphate Synthase IspF Activity JK Bitok, CF Meyers ACS chemical biology 7 (10), 1702-1710, 2012 | 52 | 2012 |
A novel method for the preparation of nucleoside triphosphates from activated nucleoside phosphoramidates W Wu, CL Freel Meyers, RF Borch Organic Letters 6 (13), 2257-2260, 2004 | 49 | 2004 |
Column chromatography CLF Meyers Current Protocols in Nucleic Acid Chemistry 3 (1), A. 3E. 1-A. 3E. 7, 2000 | 49 | 2000 |
Resistance to the Antimicrobial Agent Fosmidomycin and an FR900098 Prodrug through Mutations in the Deoxyxylulose Phosphate Reductoisomerase Gene (dxr) CM Armstrong, DJ Meyers, LS Imlay, C Freel Meyers, AR Odom Antimicrobial agents and chemotherapy 59 (9), 5511-5519, 2015 | 48 | 2015 |
DXP Synthase‐Catalyzed C N Bond Formation: Nitroso Substrate Specificity Studies Guide Selective Inhibitor Design F Morris, R Vierling, L Boucher, J Bosch, CL Freel Meyers ChemBioChem 14 (11), 1309-1315, 2013 | 47 | 2013 |
Targeting DXP synthase in human pathogens: enzyme inhibition and antimicrobial activity of butylacetylphosphonate JM Smith, NV Warrington, RJ Vierling, ML Kuhn, WF Anderson, ... The Journal of antibiotics 67 (1), 77-83, 2014 | 46 | 2014 |