A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine NC Wu, SJ Zost, AJ Thompson, D Oyen, CM Nycholat, R McBride, ... PLoS pathogens 13 (10), e1006682, 2017 | 255 | 2017 |
Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis MS Macauley, F Pfrengle, C Rademacher, CM Nycholat, AJ Gale, ... The Journal of clinical investigation 123 (7), 3074-3083, 2013 | 247 | 2013 |
Functional balance of the hemagglutinin and neuraminidase activities accompanies the emergence of the 2009 H1N1 influenza pandemic R Xu, X Zhu, R McBride, CM Nycholat, W Yu, JC Paulson, IA Wilson Journal of virology 86 (17), 9221-9232, 2012 | 215 | 2012 |
Structural characterization of the hemagglutinin receptor specificity from the 2009 H1N1 influenza pandemic R Xu, R McBride, CM Nycholat, JC Paulson, IA Wilson Journal of virology 86 (2), 982-990, 2012 | 201 | 2012 |
Preferential recognition of avian-like receptors in human influenza A H7N9 viruses R Xu, RP de Vries, X Zhu, CM Nycholat, R McBride, W Yu, JC Paulson, ... Science 342 (6163), 1230-1235, 2013 | 172 | 2013 |
Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic acid receptors X Zhu, R McBride, CM Nycholat, W Yu, JC Paulson, IA Wilson Journal of virology 86 (24), 13371-13383, 2012 | 159 | 2012 |
Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/CD169 WC Chen, N Kawasaki, CM Nycholat, S Han, J Pilotte, PR Crocker, ... PloS one 7 (6), e39039, 2012 | 145 | 2012 |
Probing the binding specificities of human Siglecs by cell-based glycan arrays C Büll, R Nason, L Sun, J Van Coillie, D Madriz Sørensen, SJ Moons, ... Proceedings of the National Academy of Sciences 118 (17), e2026102118, 2021 | 144 | 2021 |
Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation N Kawasaki, JL Vela, CM Nycholat, C Rademacher, A Khurana, ... Proceedings of the National Academy of Sciences 110 (19), 7826-7831, 2013 | 137 | 2013 |
Glycan-targeted virus-like nanoparticles for photodynamic therapy JK Rhee, M Baksh, C Nycholat, JC Paulson, H Kitagishi, MG Finn Biomacromolecules 13 (8), 2333-2338, 2012 | 118 | 2012 |
Chemical defenses of crucifers: elicitation and metabolism of phytoalexins and indole-3-acetonitrile in brown mustard and turnip MSC Pedras, CM Nycholat, S Montaut, Y Xu, AQ Khan Phytochemistry 59 (6), 611-625, 2002 | 117 | 2002 |
Therapeutic targeting of siglecs using antibody-and glycan-based approaches T Angata, CM Nycholat, MS Macauley Trends in pharmacological sciences 36 (10), 645-660, 2015 | 115 | 2015 |
Siglec-8 and Siglec-9 binding specificities and endogenous airway ligand distributions and properties H Yu, A Gonzalez-Gil, Y Wei, SM Fernandes, RN Porell, K Vajn, ... Glycobiology 27 (7), 657-668, 2017 | 101 | 2017 |
Colorful virus-like particles: fluorescent protein packaging by the Qβ capsid JK Rhee, M Hovlid, JD Fiedler, SD Brown, F Manzenrieder, H Kitagishi, ... Biomacromolecules 12 (11), 3977-3981, 2011 | 101 | 2011 |
CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen S Duan, CJ Koziol-White, WF Jester, SA Smith, CM Nycholat, ... The Journal of clinical investigation 129 (3), 2021 | 97 | 2021 |
Recognition of sialylated poly‐N‐acetyllactosamine chains on N‐and O‐linked glycans by human and avian influenza A virus hemagglutinins CM Nycholat, R McBride, DC Ekiert, R Xu, J Rangarajan, W Peng, N Razi, ... Angewandte Chemie International Edition 51 (20), 4860-4863, 2012 | 91 | 2012 |
In silico-aided design of a glycan ligand of sialoadhesin for in vivo targeting of macrophages CM Nycholat, C Rademacher, N Kawasaki, JC Paulson Journal of the American Chemical Society 134 (38), 15696-15699, 2012 | 83 | 2012 |
Preventing an antigenically disruptive mutation in egg-based H3N2 seasonal influenza vaccines by mutational incompatibility NC Wu, H Lv, AJ Thompson, DC Wu, WWS Ng, RU Kadam, CW Lin, ... Cell host & microbe 25 (6), 836-844. e5, 2019 | 76 | 2019 |
Highly pathogenic influenza A (H5Nx) viruses with altered H5 receptor-binding specificity H Guo, E de Vries, R McBride, J Dekkers, W Peng, KM Bouwman, ... Emerging Infectious Diseases 23 (2), 220, 2017 | 75 | 2017 |
Diversity of functionally permissive sequences in the receptor-binding site of influenza hemagglutinin NC Wu, J Xie, T Zheng, CM Nycholat, G Grande, JC Paulson, RA Lerner, ... Cell host & microbe 21 (6), 742-753. e8, 2017 | 73 | 2017 |