Persistent endotheliopathy in the pathogenesis of long COVID syndrome H Fogarty, L Townsend, H Morrin, A Ahmad, C Comerford, E Karampini, ... Journal of thrombosis and haemostasis 19 (10), 2546-2553, 2021 | 339 | 2021 |
Endothelial cells orchestrate COVID-19 coagulopathy JM O'Sullivan, D Mc Gonagle, SE Ward, RJS Preston, JS O'Donnell The Lancet. Haematology 7 (8), e553, 2020 | 184 | 2020 |
Severe Plasmodium falciparum Malaria Is Associated with Circulating Ultra-Large von Willebrand Multimers and ADAMTS13 Inhibition D Larkin, B de Laat, PV Jenkins, J Bunn, AG Craig, V Terraube, ... PLoS pathogens 5 (3), e1000349, 2009 | 168 | 2009 |
Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation F Ni Ainle, RJS Preston, PV Jenkins, HJ Nel, JA Johnson, OP Smith, ... Blood, The Journal of the American Society of Hematology 114 (8), 1658-1665, 2009 | 152 | 2009 |
Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels M Lavin, S Aguila, S Schneppenheim, N Dalton, KL Jones, JM O’Sullivan, ... Blood, The Journal of the American Society of Hematology 130 (21), 2344-2353, 2017 | 151 | 2017 |
Rapid activation of endothelial cells enables Plasmodium falciparum adhesion to platelet-decorated von Willebrand factor strings DJ Bridges, J Bunn, JA van Mourik, G Grau, RJS Preston, M Molyneux, ... Blood, The Journal of the American Society of Hematology 115 (7), 1472-1474, 2010 | 149 | 2010 |
Multifunctional specificity of the protein C/activated protein C Gla domain RJS Preston, E Ajzner, C Razzari, S Karageorgi, S Dua, B Dahlbäck, ... Journal of Biological Chemistry 281 (39), 28850-28857, 2006 | 130 | 2006 |
Von Willebrand factor propeptide in severe coronavirus disease 2019 (COVID‐19): evidence of acute and sustained endothelial cell activation SE Ward, GF Curley, M Lavin, H Fogarty, E Karampini, NL McEvoy, ... British journal of haematology 192 (4), 714-719, 2021 | 122 | 2021 |
Advances in understanding the molecular mechanisms that maintain normal haemostasis JS O'Donnell, JM O'Sullivan, RJS Preston British journal of haematology 186 (1), 24-36, 2019 | 113 | 2019 |
ADAMTS13 substrate recognition of von Willebrand factor A2 domain S Zanardelli, JTB Crawley, CKNCK Chion, JK Lam, RJS Preston, ... Journal of biological chemistry 281 (3), 1555-1563, 2006 | 108 | 2006 |
Expression of terminal α2-6–linked sialic acid on von Willebrand factor specifically enhances proteolysis by ADAMTS13 RT McGrath, TAJ McKinnon, B Byrne, R O'Kennedy, V Terraube, E McRae, ... Blood, The Journal of the American Society of Hematology 115 (13), 2666-2673, 2010 | 105 | 2010 |
Vitamin K–dependent protein S: beyond the protein C pathway B Dahlbäck Seminars in thrombosis and hemostasis 44 (02), 176-184, 2018 | 101 | 2018 |
Altered glycosylation of platelet-derived von Willebrand factor confers resistance to ADAMTS13 proteolysis RT McGrath, M van den Biggelaar, B Byrne, JM O’Sullivan, O Rawley, ... Blood, The Journal of the American Society of Hematology 122 (25), 4107-4110, 2013 | 99 | 2013 |
The helminth T2 RNase ω1 promotes metabolic homeostasis in an IL-33–and group 2 innate lymphoid cell–dependent mechanism E Hams, R Bermingham, FA Wurlod, AE Hogan, D O’Shea, RJ Preston, ... The FASEB Journal 30 (2), 824, 2015 | 93 | 2015 |
Elucidating the role of carbohydrate determinants in regulating hemostasis: insights and opportunities RJS Preston, O Rawley, EM Gleeson, JS O’Donnell Blood, The Journal of the American Society of Hematology 121 (19), 3801-3810, 2013 | 88 | 2013 |
Emerging roles for hemostatic dysfunction in malaria pathogenesis JM O’Sullivan, RJS Preston, N O’Regan, JS O’Donnell Blood, The Journal of the American Society of Hematology 127 (19), 2281-2288, 2016 | 84 | 2016 |
ADAMTS13 regulation of VWF multimer distribution in severe COVID‐19 SE Ward, H Fogarty, E Karampini, M Lavin, S Schneppenheim, R Dittmer, ... Journal of Thrombosis and Haemostasis 19 (8), 1914-1921, 2021 | 80 | 2021 |
Glutathione transferase omega-1 regulates NLRP3 inflammasome activation through NEK7 deglutathionylation MM Hughes, A Hooftman, S Angiari, P Tummala, Z Zaslona, MC Runtsch, ... Cell reports 29 (1), 151-161. e5, 2019 | 78 | 2019 |
A novel role for the macrophage galactose-type lectin receptor in mediating von Willebrand factor clearance SE Ward, JM O’Sullivan, C Drakeford, S Aguila, CN Jondle, J Sharma, ... Blood, The Journal of the American Society of Hematology 131 (8), 911-916, 2018 | 78 | 2018 |
The endothelial cell protein C receptor: cell surface conductor of cytoprotective coagulation factor signaling EM Gleeson, JS O’Donnell, RJS Preston Cellular and Molecular Life Sciences 69, 717-726, 2012 | 73 | 2012 |