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Natalia Putkaradze
Natalia Putkaradze
Technical University of Denmark, Novo Nordisk Foundation Center for Biosustainability
Zweryfikowany adres z biosustain.dtu.dk
Tytuł
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Cytowane przez
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Natural product C-glycosyltransferases–a scarcely characterised enzymatic activity with biotechnological potential
N Putkaradze, D Teze, F Fredslund, DH Welner
Natural product reports 38 (3), 432-443, 2021
502021
Characterization of cytochrome P450 CYP109E1 from Bacillus megaterium as a novel vitamin D3 hydroxylase
A Abdulmughni, IK Jóźwik, N Putkaradze, E Brill, J Zapp, ...
Journal of Biotechnology 243, 38-47, 2017
332017
CYP109E1 is a novel versatile statin and terpene oxidase from Bacillus megaterium
N Putkaradze, M Litzenburger, A Abdulmughni, M Milhim, E Brill, ...
Applied Microbiology and Biotechnology 101, 8379-8393, 2017
312017
Novel approach to improve progesterone hydroxylation selectivity by CYP 106A2 via rational design of adrenodoxin binding
T Sagadin, J Riehm, N Putkaradze, MC Hutter, R Bernhardt
The FEBS Journal 286 (6), 1240-1249, 2019
252019
Biotransformation of prednisone and dexamethasone by cytochrome P450 based systems–Identification of new potential drug candidates
N Putkaradze, FM Kiss, D Schmitz, J Zapp, MC Hutter, R Bernhardt
Journal of Biotechnology 242, 101-110, 2017
212017
Identification of a new plasmid-encoded cytochrome P450 CYP107DY1 from Bacillus megaterium with a catalytic activity towards mevastatin
M Milhim, N Putkaradze, A Abdulmughni, F Kern, P Hartz, R Bernhardt
Journal of Biotechnology 240, 68-75, 2016
212016
Six Uridine-Diphosphate Glycosyltransferases Catalyze the Glycosylation of Bioactive C13-Apocarotenols
G Sun, N Putkaradze, S Bohnacker, R Jonczyk, T Fida, T Hoffmann, ...
Plant Physiology 184 (4), 1744-1761, 2020
192020
Family 1 Glycosyltransferase UGT706F8 from Zea mays Selectively Catalyzes the Synthesis of Silibinin 7-O-β-d-Glucoside
GN Bidart, N Putkaradze, F Fredslund, C Kjeldsen, AG Ruiz, JØ Duus, ...
ACS Sustainable Chemistry & Engineering 10 (16), 5078-5083, 2022
142022
Highly regio-and stereoselective hydroxylation of vitamin D2 by CYP109E1
N Putkaradze, L König, L Kattner, MC Hutter, R Bernhardt
Biochemical and biophysical research communications 524 (2), 295-300, 2020
142020
CYP109E1 from Bacillus megaterium Acts as a 24‐ and 25‐Hydroxylase for Cholesterol
N Putkaradze, M Litzenburger, MC Hutter, R Bernhardt
ChemBioChem 20 (5), 655-658, 2019
142019
Structure‐guided engineering of key amino acids in UGT85B1 controlling substrate and stereo‐specificity in aromatic cyanogenic glucoside biosynthesis
R Del Giudice, N Putkaradze, BM Dos Santos, CC Hansen, C Crocoll, ...
The Plant Journal 111 (6), 1539-1549, 2022
122022
Chemoenzymatic indican for light-driven denim dyeing
GN Bidart, D Teze, CU Jansen, E Pasutto, N Putkaradze, AM Sesay, ...
Nature Communications 15 (1), 1489, 2024
72024
Sequence mining yields 18 phloretin C‐glycosyltransferases from plants for the efficient biocatalytic synthesis of nothofagin and phloretin‐di‐C‐glycoside
N Putkaradze, VD Gala, D Vaitkus, D Teze, DH Welner
Biotechnology Journal 18 (6), 2200609, 2023
62023
Enzymatic glycosylation of aloesone performed by plant UDP-dependent glycosyltransferases
N Putkaradze, L Dato, O Kırtel, J Hansen, DH Welner
Glycobiology 34 (9), cwae050, 2024
12024
Chemoenzymatic indican for sustainable light-driven denim dyeing
G Bidart, D Teze, C Jansen, E Pasutto, N Putkaradze, AM Sesay, ...
12023
Metabolism of oral turinabol by the human brain cholesterol 24-hydroxylase CYP46A1
N Putkaradze, P Hartz, MC Hutter, J Zapp, M Thevis, R Bernhardt
The Journal of Steroid Biochemistry and Molecular Biology 212, 105927, 2021
12021
A spontaneous proton transfer is key for enzymatic C-glycosylation and restricts the scope of natural C-glycosides
D Welner, L Raich, D Teze, G Bidart, F Fredslund, M Hobusch, ...
2024
Photocleavage of indican
DHW G Bidart, D teze, N Putkaradze, F Fredslund, CU Jansen, K Qvortrup
WO Patent WO2024052526A1, 2024
2024
FUNCTIONAL AND STRUCTURAL CHARACTERIZATION OF CHOLESTEROL-, VITAMIN D-2-AND D-3-HYDROXYLASES FROM BACILLUS MEGATERIUM
N Putkaradze, A Abdulmughni, IK Jozwik, L Kattner, J Zapp, MC Hutter, ...
ANTICANCER RESEARCH 42 (4), 2194-2195, 2022
2022
A hyperstable glycosyltransferase for blue denim dyeing
G Bidart, N Putkaradze, D Teze, L Lo Leggio, S Sukumara, ...
2022
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