Hypoxic pulmonary vasoconstriction: from molecular mechanisms to medicine KJ Dunham-Snary, D Wu, EA Sykes, A Thakrar, LRG Parlow, JD Mewburn, ... Chest 151 (1), 181-192, 2017 | 502 | 2017 |
MicroRNA-138 and microRNA-25 down-regulate mitochondrial calcium uniporter, causing the pulmonary arterial hypertension cancer phenotype Z Hong, KH Chen, A DasGupta, F Potus, K Dunham-Snary, S Bonnet, ... American journal of respiratory and critical care medicine 195 (4), 515-529, 2017 | 146 | 2017 |
Epigenetic dysregulation of the dynamin-related protein 1 binding partners MiD49 and MiD51 increases mitotic mitochondrial fission and promotes pulmonary arterial hypertension … KH Chen, A Dasgupta, J Lin, F Potus, S Bonnet, J Iremonger, J Fu, ... Circulation 138 (3), 287-304, 2018 | 145 | 2018 |
Canine hindlimb blood flow and O2 uptake after inhibition of EDRF/NO synthesis CE King, MJ Melinyshyn, JD Mewburn, SE Curtis, MJ Winn, SM Cain, ... Journal of applied physiology 76 (3), 1166-1171, 1994 | 138 | 1994 |
Epigenetic metabolic reprogramming of right ventricular fibroblasts in pulmonary arterial hypertension: a pyruvate dehydrogenase kinase-dependent shift in mitochondrial … L Tian, D Wu, A Dasgupta, KH Chen, J Mewburn, F Potus, PDA Lima, ... Circulation research 126 (12), 1723-1745, 2020 | 126 | 2020 |
Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension F Potus, MW Pauciulo, EK Cook, N Zhu, A Hsieh, CL Welch, Y Shen, ... Circulation 141 (24), 1986-2000, 2020 | 112 | 2020 |
The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease K Atkins, A Dasgupta, KH Chen, J Mewburn, SL Archer Clinical Science 130 (21), 1861-1874, 2016 | 112 | 2016 |
Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension L Tian, M Neuber-Hess, J Mewburn, A Dasgupta, K Dunham-Snary, D Wu, ... Journal of molecular medicine 95, 381-393, 2017 | 111 | 2017 |
Macrophage–NLRP3 activation promotes right ventricle failure in pulmonary arterial hypertension R Al-Qazazi, PDA Lima, SZ Prisco, F Potus, A Dasgupta, KH Chen, L Tian, ... American journal of respiratory and critical care medicine 206 (5), 608-624, 2022 | 102 | 2022 |
Histones link inflammation and thrombosis through the induction of Weibel–Palade body exocytosis A Michels, S Albánez, J Mewburn, K Nesbitt, TJ Gould, PC Liaw, ... Journal of Thrombosis and Haemostasis 14 (11), 2274-2286, 2016 | 97 | 2016 |
Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury D Wu, A Dasgupta, KH Chen, M Neuber‐Hess, J Patel, TE Hurst, ... The FASEB Journal 34 (1), 1447-1464, 2020 | 95 | 2020 |
Ndufs2, a core subunit of mitochondrial complex I, is essential for acute oxygen-sensing and hypoxic pulmonary vasoconstriction KJ Dunham-Snary, D Wu, F Potus, EA Sykes, JD Mewburn, RL Charles, ... Circulation research 124 (12), 1727-1746, 2019 | 95 | 2019 |
Sperm‐borne protein, PAWP, initiates zygotic development in Xenopus laevis by eliciting intracellular calcium release M Aarabi, Z Qin, W Xu, J Mewburn, R Oko Molecular Reproduction and Development: Incorporating Gamete Research 77 (3 …, 2010 | 85 | 2010 |
The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity LL Swystun, JD Lai, C Notley, I Georgescu, AS Paine, J Mewburn, ... The Journal of clinical investigation 128 (9), 4057-4073, 2018 | 80 | 2018 |
Increased Drp1-mediated mitochondrial fission promotes proliferation and collagen production by right ventricular fibroblasts in experimental pulmonary arterial hypertension L Tian, F Potus, D Wu, A Dasgupta, KH Chen, J Mewburn, P Lima, ... Frontiers in physiology 9, 828, 2018 | 79 | 2018 |
Cysteinyl leukotriene 2 receptor‐mediated vascular permeability via transendothelial vesicle transport MPW Moos, JD Mewburn, FWK Kan, S Ishii, M Abe, K Sakimura, ... The FASEB Journal 22 (12), 4352-4362, 2008 | 58 | 2008 |
Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling AL Theilmann, LG Hawke, LR Hilton, MKM Whitford, DV Cole, JL Mackeil, ... Arteriosclerosis, Thrombosis, and Vascular Biology 40 (11), 2605-2618, 2020 | 53 | 2020 |
Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer D Wu, A Dasgupta, AD Read, RET Bentley, M Motamed, KH Chen, ... Free Radical Biology and Medicine 170, 150-178, 2021 | 52 | 2021 |
Mitochondria in human neutrophils mediate killing of Staphylococcus aureus KJ Dunham-Snary, BGJ Surewaard, JD Mewburn, RET Bentley, AY Martin, ... Redox biology 49, 102225, 2022 | 51 | 2022 |
Renal and cardiovascular characterization of COX-2 knockdown mice F Seta, AD Chung, PV Turner, JD Mewburn, Y Yu, CD Funk American Journal of Physiology-Regulatory, Integrative and Comparative …, 2009 | 51 | 2009 |