| GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport BD Freibaum, Y Lu, R Lopez-Gonzalez, NC Kim, S Almeida, KH Lee, ... Nature 525 (7567), 129-133, 2015 | 930 | 2015 |
| Poly (GR) in C9ORF72-related ALS/FTD compromises mitochondrial function and increases oxidative stress and DNA damage in iPSC-derived motor neurons R Lopez-Gonzalez, Y Lu, TF Gendron, A Karydas, H Tran, D Yang, ... Neuron 92 (2), 383-391, 2016 | 465 | 2016 |
| Differential toxicity of nuclear RNA foci versus dipeptide repeat proteins in a Drosophila model of C9ORF72 FTD/ALS H Tran, S Almeida, J Moore, TF Gendron, UD Chalasani, Y Lu, X Du, ... Neuron 87 (6), 1207-1214, 2015 | 256 | 2015 |
| Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations Z Zhang, S Almeida, Y Lu, AL Nishimura, L Peng, D Sun, B Wu, ... PloS one 8 (10), e76055, 2013 | 173 | 2013 |
| FTD/ALS-associated poly (GR) protein impairs the Notch pathway and is recruited by poly (GA) into cytoplasmic inclusions D Yang, A Abdallah, Z Li, Y Lu, S Almeida, FB Gao Acta neuropathologica 130, 525-535, 2015 | 162 | 2015 |
| Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching Y Lu, J Ferris, FB Gao Molecular brain 2, 1-10, 2009 | 160 | 2009 |
| Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia RJH West, Y Lu, B Marie, FB Gao, ST Sweeney Journal of Cell Biology 208 (7), 931-947, 2015 | 91 | 2015 |
| The Drosophila homologue of the Angelman syndrome ubiquitin ligase regulates the formation of terminal dendritic branches Y Lu, F Wang, Y Li, J Ferris, JA Lee, FB Gao Human Molecular Genetics 18 (3), 454-462, 2009 | 88 | 2009 |
| Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal dementia, is required for autophagosome maturation Y Lu, Z Zhang, D Sun, ST Sweeney, FB Gao Molecular cell 52 (2), 264-271, 2013 | 75 | 2013 |
| Neurophysiological Defects and Neuronal Gene Deregulation in Drosophila mir-124 Mutants K Sun, JO Westholm, K Tsurudome, JW Hagen, Y Lu, M Kohwi, D Betel, ... PLoS Genetics 8 (2), e1002515, 2012 | 67 | 2012 |
| The FTD/ALS associated RNA binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila Z Li, Y Lu, XL Xu, FB Gao Human Molecular Genetics, 2012 | 49 | 2012 |
| The AKAP Yu is required for olfactory long-term memory formation in Drosophila Y Lu, YS Lu, Y Shuai, C Feng, T Tully, Z Xie, Y Zhong, HM Zhou Proceedings of the National Academy of Sciences 104 (34), 13792, 2007 | 38 | 2007 |
| Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS P González-Pérez, Y Lu, RJ Chian, PC Sapp, RE Tanzi, L Bertram, ... Neurobiology of Disease, 2012 | 26 | 2012 |
| Damaged mitochondria coincide with presynaptic vesicle loss and abnormalities in alzheimer’s disease brain W Wang, F Zhao, Y Lu, SL Siedlak, H Fujioka, H Feng, G Perry, X Zhu Acta Neuropathologica Communications 11 (1), 54, 2023 | 25 | 2023 |
| Oxidative stress signaling in blast TBI-induced Tau phosphorylation C Wang, C Shao, L Zhang, SL Siedlak, JS Meabon, ER Peskind, Y Lu, ... Antioxidants 10 (6), 955, 2021 | 15 | 2021 |
| Purification and characterization of Cr-containing nitrogenase component I HJ Fu, DZ Gang, ZH Feng, LY Bing, Z Ying, WZ Ping Journal of Integrative Plant Biology 44 (3), 297, 2002 | 13 | 2002 |
| A role for presenilin in post‐stress regulation: effects of presenilin mutations on Ca2+ currents in Drosophila Y Lu, Y Lv, Y Ye, Y Wang, Y Hong, ME Fortini, Y Zhong, Z Xie The FASEB Journal 21 (10), 2368-2378, 2007 | 11 | 2007 |
| Ik2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant CHMP2B toxicity in Drosophila Y Lu, RJH West, M Pons, ST Sweeney, FB Gao Scientific Reports 10 (1), 14221, 2020 | 9 | 2020 |
| Bezafibrate confers neuroprotection in the 5xFAD mouse model of Alzheimer's disease Y Lu, H Fujioka, W Wang, X Zhu Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1869 (8), 166841, 2023 | 8 | 2023 |
| TBK1 haploinsufficiency in ALS and FTD compromises membrane trafficking Y Lu, FB Almeida, Sandra & Gao Acta Neuropathologica, 2021 | 8 | 2021 |
