| Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial RECOVERY Collaborative Group Lancet (London, England) 397 (10285), 1637, 2021 | 2877* | 2021 |
| A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome J Guy, B Hendrich, M Holmes, JE Martin, A Bird Nature genetics 27 (3), 322-326, 2001 | 1782 | 2001 |
| 11β-Hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress Y Kotelevtsev, MC Holmes, A Burchell, PM Houston, D Schmoll, ... Proceedings of the National Academy of Sciences 94 (26), 14924-14929, 1997 | 1149 | 1997 |
| Mechanisms of disease: glucocorticoids, their placental metabolism and fetal'programming'of adult pathophysiology JR Seckl, MC Holmes Nature clinical practice Endocrinology & metabolism 3 (6), 479-488, 2007 | 1028 | 2007 |
| 11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action K Chapman, M Holmes, J Seckl Physiological reviews 93 (3), 1139-1206, 2013 | 977 | 2013 |
| Dexamethasone in the last week of pregnancy attenuates hippocampal glucocorticoid receptor gene expression and elevates blood pressure in the adult offspring in the rat NS Levitt, RS Lindsay, MC Holmes, JR Seckl Neuroendocrinology 64 (6), 412-418, 1996 | 665 | 1996 |
| RECOVERY Collaborative Group Dexamethasone in hospitalized patients with Covid-19 P Horby, WS Lim, JR Emberson, M Mafham, JL Bell, L Linsell, N Staplin, ... N Engl J Med 384 (8), 693-704, 2021 | 638* | 2021 |
| Novel adipose tissue–mediated resistance to diet-induced visceral obesity in 11β-hydroxysteroid dehydrogenase type 1–deficient mice NM Morton, JM Paterson, H Masuzaki, MC Holmes, B Staels, C Fievet, ... Diabetes 53 (4), 931-938, 2004 | 638 | 2004 |
| Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11β-hydroxysteroid dehydrogenase type 1 null mice NM Morton, MC Holmes, C Fiévet, B Staels, A Tailleux, JJ Mullins, ... Journal of Biological Chemistry 276 (44), 41293-41300, 2001 | 612 | 2001 |
| Metabolic syndrome without obesity: hepatic overexpression of 11β-hydroxysteroid dehydrogenase type 1 in transgenic mice JM Paterson, NM Morton, C Fievet, CJ Kenyon, MC Holmes, B Staels, ... Proceedings of the National Academy of Sciences 101 (18), 7088-7093, 2004 | 574 | 2004 |
| Prenatal glucocorticoid programming of brain corticosteroid receptors and corticotrophin-releasing hormone: possible implications for behaviour LAM Welberg, JR Seckl, MC Holmes Neuroscience 104 (1), 71-79, 2001 | 501 | 2001 |
| Inhibition of 11β‐hydroxysteroid dehydrogenase, the foeto‐placental barrier to maternal glucocorticoids, permanently programs amygdala GR mRNA expression and anxiety‐like … LAM Welberg, JR Seckl, MC Holmes European Journal of Neuroscience 12 (3), 1047-1054, 2000 | 447 | 2000 |
| Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study RA Evans, OC Leavy, M Richardson, O Elneima, HJC McAuley, ... The Lancet Respiratory Medicine 10 (8), 761-775, 2022 | 384 | 2022 |
| Mineralocorticoid and glucocorticoid receptor balance in control of HPA axis and behaviour AP Harris, MC Holmes, ER De Kloet, KE Chapman, JR Seckl Psychoneuroendocrinology 38 (5), 648-658, 2013 | 283 | 2013 |
| 11β-hydroxysteroid dehydrogenases and the brain: from zero to hero, a decade of progress CS Wyrwoll, MC Holmes, JR Seckl Frontiers in neuroendocrinology 32 (3), 265-286, 2011 | 281 | 2011 |
| Intracellular regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase (11β-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis … HJ Harris, Y Kotelevtsev, JJ Mullins, JR Seckl, MC Holmes Endocrinology 142 (1), 114-120, 2001 | 279 | 2001 |
| Prenatal dexamethasone exposure induces changes in nonhuman primate offspring cardiometabolic and hypothalamic-pituitary-adrenal axis function A de Vries, MC Holmes, A Heijnis, JV Seier, J Heerden, J Louw, ... The Journal of clinical investigation 117 (4), 1058-1067, 2007 | 277 | 2007 |
| Glucocorticoid exposure in late gestation in the rat permanently programs gender-specific differences in adult cardiovascular and metabolic physiology D O'Regan, CJ Kenyon, JR Seckl, MC Holmes American Journal of Physiology-Endocrinology and Metabolism 287 (5), E863-E870, 2004 | 276 | 2004 |
| The mother or the fetus? 11β-hydroxysteroid dehydrogenase type 2 null mice provide evidence for direct fetal programming of behavior by endogenous glucocorticoids MC Holmes, CT Abrahamsen, KL French, JM Paterson, JJ Mullins, ... Journal of Neuroscience 26 (14), 3840-3844, 2006 | 253 | 2006 |
| Magnocellular axons in passage through the median eminence release vasopressin MC Holmes, FA Antoni, G Aguilera, KJ Catt Nature 319 (6051), 326-329, 1986 | 244 | 1986 |
