| On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system A Adamo, RL Beingessner, M Behnam, J Chen, TF Jamison, KF Jensen, ... Science 352 (6281), 61-67, 2016 | 1007 | 2016 |
| A three‐minute synthesis and purification of ibuprofen: Pushing the limits of continuous‐flow processing DR Snead, TF Jamison Angewandte Chemie International Edition 54 (3), 983-987, 2015 | 271 | 2015 |
| End-to-end continuous flow synthesis and purification of diphenhydramine hydrochloride featuring atom economy, in-line separation, and flow of molten ammonium salts DR Snead, TF Jamison Chemical Science 4 (7), 2822-2827, 2013 | 123 | 2013 |
| Scaling continuous API synthesis from milligram to kilogram: extending the enabling benefits of micro to the plant M Berton, JM de Souza, I Abdiaj, DT McQuade, DR Snead Journal of Flow Chemistry 10, 73-92, 2020 | 72 | 2020 |
| Recent developments of chiral diaminocarbene-metal complexes for asymmetric catalysis DR Snead, H Seo, S Hong Current Organic Chemistry 12 (16), 1370-1387, 2008 | 67 | 2008 |
| A concise route to MK-4482 (EIDD-2801) from cytidine N Vasudevan, GP Ahlqvist, CP McGeough, DJ Paymode, FSP Cardoso, ... Chemical Communications 56 (87), 13363-13364, 2020 | 58 | 2020 |
| Bis (2-alkylpyrrolidin-1-yl) methylidenes as chiral acyclic diaminocarbene ligands DR Snead, S Inagaki, KA Abboud, S Hong Organometallics 29 (7), 1729-1739, 2010 | 58 | 2010 |
| Continuous-flow synthesis and purification of atropine with sequential in-line separations of structurally similar impurities C Dai, DR Snead, P Zhang, TF Jamison Journal of Flow Chemistry 5 (3), 133-138, 2015 | 53 | 2015 |
| Progress toward a large-scale synthesis of molnupiravir (MK-4482, EIDD-2801) from cytidine GP Ahlqvist, CP McGeough, C Senanayake, JD Armstrong, A Yadaw, ... ACS omega 6 (15), 10396-10402, 2021 | 50 | 2021 |
| A new route to acyclic diaminocarbenes via lithium− halogen exchange DR Snead, I Ghiviriga, KA Abboud, S Hong Organic Letters 11 (15), 3274-3277, 2009 | 47 | 2009 |
| Toward a practical, two-step process for molnupiravir: Direct hydroxamination of cytidine followed by selective esterification DJ Paymode, N Vasudevan, S Ahmad, AL Kadam, FSP Cardoso, ... Organic Process Research & Development 25 (8), 1822-1830, 2021 | 45 | 2021 |
| Expanding access to remdesivir via an improved pyrrolotriazine synthesis: supply centered synthesis DJ Paymode, FSP Cardoso, T Agrawal, JW Tomlin, DW Cook, JM Burns, ... Organic Letters 22 (19), 7656-7661, 2020 | 37 | 2020 |
| A high‐yielding synthesis of EIDD‐2801 from Uridine A Steiner, D Znidar, SB Ötvös, DR Snead, D Dallinger, CO Kappe European Journal of Organic Chemistry 2020 (43), 6736-6739, 2020 | 36 | 2020 |
| A Concise Route to MK-4482 (EIDD-2801) from Cytidine: Part 2 V Gopalsamuthiram, C Williams, J Noble, TF Jamison, BF Gupton, ... Synlett 32 (03), 326-328, 2021 | 35 | 2021 |
| Bulky acyclic aminooxycarbene ligands H Seo, DR Snead, KA Abboud, S Hong Organometallics 30 (21), 5725-5730, 2011 | 31 | 2011 |
| An efficient synthesis of tenofovir (PMPA): A key intermediate leading to tenofovir-based HIV medicines BP Derstine, JW Tomlin, CL Peck, JP Dietz, BT Herrera, FSP Cardoso, ... Organic Process Research & Development 24 (8), 1420-1427, 2020 | 26 | 2020 |
| In situ generation of novel acyclic diaminocarbene–copper complex D Hirsch-Weil, DR Snead, S Inagaki, H Seo, KA Abboud, S Hong Chemical Communications, 2475-2477, 2009 | 22 | 2009 |
| One-step synthesis of 2-fluoroadenine using hydrogen fluoride pyridine in a continuous flow operation N Salehi Marzijarani, DR Snead, JP McMullen, F Lévesque, M Weisel, ... Organic Process Research & Development 23 (8), 1522-1528, 2019 | 21 | 2019 |
| Toward a practical, nonenzymatic process for investigational COVID-19 antiviral molnupiravir from cytidine: Supply-centered synthesis V Gopalsamuthiram, AL Kadam, JK Noble, DR Snead, C Williams, ... Organic process research & development 25 (12), 2679-2685, 2021 | 20 | 2021 |
| Synthesis of an Oxathiolane drug substance intermediate guided by constraint-driven innovation K Kashinath, DR Snead, JM Burns, RW Stringham, BF Gupton, ... Organic Process Research & Development 24 (10), 2266-2270, 2020 | 17 | 2020 |
