Structural principles of distinct assemblies of the human α4β2 nicotinic receptor RM Walsh Jr, SH Roh, A Gharpure, CL Morales-Perez, J Teng, RE Hibbs Nature 557 (7704), 261-265, 2018 | 221 | 2018 |
Tarantula toxins interact with voltage sensors within lipid membranes M Milescu, J Vobecky, SH Roh, SH Kim, HJ Jung, JI Kim, KJ Swartz The Journal of general physiology 130 (5), 497-511, 2007 | 147 | 2007 |
The chaperonin TRiC/CCT associates with prefoldin through a conserved electrostatic interface essential for cellular proteostasis D Gestaut, SH Roh, B Ma, G Pintilie, LA Joachimiak, A Leitner, ... Cell 177 (3), 751-765. e15, 2019 | 136 | 2019 |
Vortical flow over the free end surface of a finite circular cylinder mounted on a flat plate SC Roh, S Park Experiments in fluids 34 (1), 63-67, 2003 | 129 | 2003 |
Solution Structure and Functional Characterization of SGTx1, a Modifier of Kv2.1 Channel Gating, CW Lee, S Kim, SH Roh, H Endoh, Y Kodera, T Maeda, T Kohno, ... Biochemistry 43 (4), 890-897, 2004 | 124 | 2004 |
Molecular surface of tarantula toxins interacting with voltage sensors in Kv channels JM Wang, SH Roh, S Kim, CW Lee, JI Kim, KJ Swartz Journal of General Physiology 123 (4), 455-467, 2004 | 123 | 2004 |
The 3.5-Å CryoEM structure of nanodisc-reconstituted yeast vacuolar ATPase Vo proton channel SH Roh, NJ Stam, CF Hryc, S Couoh-Cardel, G Pintilie, W Chiu, ... Molecular cell 69 (6), 993-1004. e3, 2018 | 117 | 2018 |
Modulation of STAT3 folding and function by TRiC/CCT chaperonin M Kasembeli, WCY Lau, SH Roh, TK Eckols, J Frydman, W Chiu, ... PLoS biology 12 (4), e1001844, 2014 | 116 | 2014 |
Subunit conformational variation within individual GroEL oligomers resolved by Cryo-EM SH Roh, CF Hryc, HH Jeong, X Fei, J Jakana, GH Lorimer, W Chiu Proceedings of the National Academy of Sciences 114 (31), 8259-8264, 2017 | 102 | 2017 |
Contribution of the type II chaperonin, TRiC/CCT, to oncogenesis SH Roh, M Kasembeli, D Bakthavatsalam, W Chiu, DJ Tweardy International journal of molecular sciences 16 (11), 26706-26720, 2015 | 86 | 2015 |
Improved peak detection and deconvolution of native electrospray mass spectra from large protein complexes J Lu, MJ Trnka, SH Roh, PJJ Robinson, C Shiau, DG Fujimori, W Chiu, ... Journal of the American Society for Mass Spectrometry 26 (12), 2141-2151, 2015 | 81 | 2015 |
Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition CS Huang, X Yu, P Fordstrom, K Choi, BC Chung, SH Roh, W Chiu, ... Science advances 6 (25), eabb1989, 2020 | 78 | 2020 |
Structure of the human DICER–pre-miRNA complex in a dicing state YY Lee, H Lee, H Kim, VN Kim, SH Roh Nature 615 (7951), 331-338, 2023 | 73 | 2023 |
Reprogramming an ATP-driven protein machine into a light-gated nanocage D Hoersch, SH Roh, W Chiu, T Kortemme Nature nanotechnology 8 (12), 928-932, 2013 | 69 | 2013 |
Mapping the catalytic conformations of an assembly-line polyketide synthase module DP Cogan, K Zhang, X Li, S Li, GD Pintilie, SH Roh, CS Craik, W Chiu, ... Science 374 (6568), 729-734, 2021 | 62 | 2021 |
Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of Vo complex SH Roh, M Shekhar, G Pintilie, C Chipot, S Wilkens, A Singharoy, W Chiu Science Advances 6 (41), eabb9605, 2020 | 59 | 2020 |
Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT D Gestaut, Y Zhao, J Park, B Ma, A Leitner, M Collier, G Pintilie, SH Roh, ... Cell 185 (25), 4770-4787. e20, 2022 | 50 | 2022 |
Cryo-EM structures of the Hsp104 protein disaggregase captured in the ATP conformation S Lee, SH Roh, J Lee, N Sung, J Liu, FTF Tsai Cell reports 26 (1), 29-36. e3, 2019 | 42 | 2019 |
A crystal structure of the cyclic GMP-dependent protein kinase I{beta} dimerization/docking domain reveals molecular details of isoform-specific anchoring. KC Casteel DE1, Smith-Nguyen EV, Sankaran B, Roh SH, Pilz RB J Biol Chem 285 (43), 32684-8, 2010 | 41 | 2010 |
Chaperonin TRiC/CCT modulates the folding and activity of leukemogenic fusion oncoprotein AML1-ETO SH Roh, M Kasembeli, JG Galaz-Montoya, M Trnka, WCY Lau, ... Journal of Biological Chemistry 291 (9), 4732-4741, 2016 | 37 | 2016 |