Kinetic analysis of PRMT1 reveals multifactorial processivity and a sequential ordered mechanism JI Brown, T Koopmans, J van Strien, NI Martin, A Frankel ChemBioChem 19 (1), 85-99, 2018 | 27 | 2018 |
Evaluation of kinetic data: What the numbers tell us about PRMTs A Frankel, JI Brown Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (3), 306-316, 2019 | 19 | 2019 |
Protein arginine methyltransferase 8 modulates mitochondrial bioenergetics and neuroinflammation after hypoxic stress A Couto E Silva, CY Wu, GA Clemons, CH Acosta, CT Chen, HLE Possoit, ... Journal of neurochemistry 159 (4), 742-761, 2021 | 14 | 2021 |
The application of differential scanning fluorimetry in exploring bisubstrate binding to protein arginine N-methyltransferase 1 JI Brown, BDG Page, A Frankel Methods 175, 10-23, 2020 | 12 | 2020 |
Chemically engineering the drug release rate of a PEG-paclitaxel conjugate using click and steric hindrance chemistries for optimal efficacy A Nguyen, PH Chao, CY Ong, E Rouhollahi, NAL Fayez, L Lin, JI Brown, ... Biomaterials 289, 121735, 2022 | 9 | 2022 |
Cycloguanil and analogues potently target DHFR in cancer cells to elicit anti-cancer activity JI Brown, P Wang, AYL Wong, B Petrova, R Persaud, S Soukhtehzari, ... Metabolites 13 (2), 151, 2023 | 7 | 2023 |
Investigating the anti-cancer potential of pyrimethamine analogues through a modern chemical biology lens JI Brown, R Persaud, P Iliev, U Karmacharya, S Attarha, H Sahile, ... European Journal of Medicinal Chemistry 264, 115971, 2024 | 5 | 2024 |
Pyrimethamine inhibits STAT3 transcriptional activity via dihydrofolate reductase LN Heppler, SR Walker, S Attarha, BD Page, DA Frank Cancer Research 79 (13_Supplement), 387-387, 2019 | 3 | 2019 |
Methylarginine efflux in nutrient-deprived yeast mitigates disruption of nitric oxide synthesis JI Brown, J Alibhai, E Zhu, A Frankel Amino Acids 55 (2), 215-233, 2023 | | 2023 |
The mechanism of Hepatocyte-Targeting and safety profile of Phospholipid-Free small unilamellar vesicles NAL Fayez, R Böttger, J Brown, E Rouhollahi, SD Li International Journal of Pharmaceutics 628, 122269, 2022 | | 2022 |
Cover Feature: Kinetic Analysis of PRMT1 Reveals Multifactorial Processivity and a Sequential Ordered Mechanism (ChemBioChem 1/2018) JI Brown, T Koopmans, J van Strien, NI Martin, A Frankel ChemBioChem 19 (1), 2-2, 2018 | | 2018 |