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Jennifer I Brown
Tytuł
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Kinetic analysis of PRMT1 reveals multifactorial processivity and a sequential ordered mechanism
JI Brown, T Koopmans, J van Strien, NI Martin, A Frankel
ChemBioChem 19 (1), 85-99, 2018
272018
Evaluation of kinetic data: What the numbers tell us about PRMTs
A Frankel, JI Brown
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (3), 306-316, 2019
192019
Protein arginine methyltransferase 8 modulates mitochondrial bioenergetics and neuroinflammation after hypoxic stress
A Couto E Silva, CY Wu, GA Clemons, CH Acosta, CT Chen, HLE Possoit, ...
Journal of neurochemistry 159 (4), 742-761, 2021
142021
The application of differential scanning fluorimetry in exploring bisubstrate binding to protein arginine N-methyltransferase 1
JI Brown, BDG Page, A Frankel
Methods 175, 10-23, 2020
122020
Chemically engineering the drug release rate of a PEG-paclitaxel conjugate using click and steric hindrance chemistries for optimal efficacy
A Nguyen, PH Chao, CY Ong, E Rouhollahi, NAL Fayez, L Lin, JI Brown, ...
Biomaterials 289, 121735, 2022
92022
Cycloguanil and analogues potently target DHFR in cancer cells to elicit anti-cancer activity
JI Brown, P Wang, AYL Wong, B Petrova, R Persaud, S Soukhtehzari, ...
Metabolites 13 (2), 151, 2023
72023
Investigating the anti-cancer potential of pyrimethamine analogues through a modern chemical biology lens
JI Brown, R Persaud, P Iliev, U Karmacharya, S Attarha, H Sahile, ...
European Journal of Medicinal Chemistry 264, 115971, 2024
52024
Pyrimethamine inhibits STAT3 transcriptional activity via dihydrofolate reductase
LN Heppler, SR Walker, S Attarha, BD Page, DA Frank
Cancer Research 79 (13_Supplement), 387-387, 2019
32019
Methylarginine efflux in nutrient-deprived yeast mitigates disruption of nitric oxide synthesis
JI Brown, J Alibhai, E Zhu, A Frankel
Amino Acids 55 (2), 215-233, 2023
2023
The mechanism of Hepatocyte-Targeting and safety profile of Phospholipid-Free small unilamellar vesicles
NAL Fayez, R Böttger, J Brown, E Rouhollahi, SD Li
International Journal of Pharmaceutics 628, 122269, 2022
2022
Cover Feature: Kinetic Analysis of PRMT1 Reveals Multifactorial Processivity and a Sequential Ordered Mechanism (ChemBioChem 1/2018)
JI Brown, T Koopmans, J van Strien, NI Martin, A Frankel
ChemBioChem 19 (1), 2-2, 2018
2018
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