| Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2 A Zoccarato, NC Surdo, JM Aronsen, LA Fields, L Mancuso, G Dodoni, ... Circulation research 117 (8), 707-719, 2015 | 142 | 2015 |
| Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)–HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes YY Sin, HV Edwards, X Li, JP Day, F Christian, AJ Dunlop, DR Adams, ... Journal of molecular and cellular cardiology 50 (5), 872-883, 2011 | 117 | 2011 |
| Basement membrane collagens and disease mechanisms A Gatseva, YY Sin, G Brezzo, T Van Agtmael Essays in biochemistry 63 (3), 297-312, 2019 | 102 | 2019 |
| Arginase-1 deficiency YY Sin, G Baron, A Schulze, CD Funk Journal of molecular medicine 93 (12), 1287-1296, 2015 | 100 | 2015 |
| Specific interactions between Epac1, β-arrestin2 and PDE4D5 regulate β-adrenergic receptor subtype differential effects on cardiac hypertrophic signaling M Berthouze-Duquesnes, A Lucas, A Saulière, YY Sin, AC Laurent, ... Cellular signalling 25 (4), 970-980, 2013 | 81 | 2013 |
| β-Arrestin 1 inhibits the GTPase-activating protein function of ARHGAP21, promoting activation of RhoA following angiotensin II type 1A receptor stimulation DF Anthony, YY Sin, S Vadrevu, N Advant, JP Day, AM Byrne, MJ Lynch, ... Molecular and cellular biology 31 (5), 1066-1075, 2011 | 76 | 2011 |
| Inducible arginase 1 deficiency in mice leads to hyperargininemia and altered amino acid metabolism YY Sin, LL Ballantyne, K Mukherjee, T St. Amand, L Kyriakopoulou, ... Plos one 8 (11), e80001, 2013 | 55 | 2013 |
| Small heat shock protein 20 (Hsp20) facilitates nuclear import of protein kinase D 1 (PKD1) during cardiac hypertrophy YY Sin, TP Martin, L Wills, S Currie, GS Baillie Cell Communication and Signaling 13, 1-11, 2015 | 37 | 2015 |
| Liver-specific knockout of arginase-1 leads to a profound phenotype similar to inducible whole body arginase-1 deficiency LL Ballantyne, YY Sin, OY Al-Dirbashi, X Li, DJ Hurlbut, CD Funk Molecular genetics and metabolism reports 9, 54-60, 2016 | 31 | 2016 |
| Molecular analysis of polymerase gamma gene and mitochondrial polymorphism in fertile and subfertile men TP Harris, KP Gomas, F Weir, AJ Holyoake, P McHugh, M Wu, Y Sin, ... International journal of andrology 29 (3), 421-433, 2006 | 29 | 2006 |
| Proof-of-concept gene editing for the murine model of inducible arginase-1 deficiency YY Sin, PR Price, LL Ballantyne, CD Funk Scientific Reports 7 (1), 2585, 2017 | 22 | 2017 |
| Protein kinase D in the hypertrophy pathway YY Sin, GS Baillie Biochemical Society Transactions 40 (1), 287-289, 2012 | 22 | 2012 |
| Strategies to rescue the consequences of inducible arginase-1 deficiency in mice LL Ballantyne, YY Sin, T St. Amand, J Si, S Goossens, L Haenebalcke, ... Plos one 10 (5), e0125967, 2015 | 16 | 2015 |
| Transplantation of gene-edited hepatocyte-like cells modestly improves survival of arginase-1-deficient mice YY Sin, LL Ballantyne, CR Richmond, CD Funk Molecular Therapy Nucleic Acids 10, 122-130, 2018 | 13 | 2018 |
| Heat shock protein 20 (HSP20) is a novel substrate for protein kinase D1 (PKD1) YY Sin, GS Baillie Cell Biochemistry and Function 33 (7), 421-426, 2015 | 12 | 2015 |
| Material-driven fibronectin assembly rescues matrix defects due to mutations in collagen IV in fibroblasts EN Mpoyi, M Cantini, YY Sin, L Fleming, DW Zhou, M Costell, Y Lu, ... Biomaterials 252, 120090, 2020 | 10 | 2020 |
| ARHGAP21, promoting activation of RhoA following angiotensin II Type 1A receptor stimulation D Anthony, Y Sin, S Vadrevu, N Advant, J Day, A Byrne, MJ Lynch, ... Mol Cell Biol 31, 1066-75, 2011 | 3 | 2011 |
| Beta‐amyloid interacts with and activates the long‐form phosphodiesterase PDE4D5 in neuronal cells to reduce cAMP availability YY Sin, RT Cameron, M Schepers, R MacLeod, TA Wright, D Paes, ... FEBS letters 598 (13), 1591-1604, 2024 | 2 | 2024 |
| Targeted protein degradation of PDE4 shortforms by a novel proteolysis targeting chimera YY Sin, A Giblin, A Judina, P Rujirachaivej, LG Corral, E Glennon, ZX Tai, ... The FEBS Journal, 2024 | 1 | 2024 |
| Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage S McNeilly, CR Thomson, L Gonzalez-Trueba, YY Sin, A Granata, ... EBioMedicine 107, 2024 | 1 | 2024 |
