SNAREpins: minimal machinery for membrane fusion T Weber, BV Zemelman, JA McNew, B Westermann, M Gmachl, F Parlati, ... Cell 92 (6), 759-772, 1998 | 3027 | 1998 |
Cathepsin D targeted by acid sphingomyelinase‐derived ceramide M Heinrich, M Wickel, W Schneider‐Brachert, C Sandberg, J Gahr, ... The EMBO journal, 1999 | 459 | 1999 |
Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs WC Tucker, T Weber, ER Chapman Science 304 (5669), 435-438, 2004 | 450 | 2004 |
Pre-existing anti–adeno-associated virus antibodies as a challenge in AAV gene therapy V Louis Jeune, JA Joergensen, RJ Hajjar, T Weber Human gene therapy methods 24 (2), 59-67, 2013 | 388 | 2013 |
Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors JA McNew, T Weber, F Parlati, RJ Johnston, TJ Melia, TH Söllner, ... The Journal of cell biology 150 (1), 105-118, 2000 | 384 | 2000 |
Intracellular transport of recombinant adeno-associated virus vectors M Nonnenmacher, T Weber Gene therapy 19 (6), 649-658, 2012 | 338 | 2012 |
Rapid and efficient fusion of phospholipid vesicles by the α-helical core of a SNARE complex in the absence of an N-terminal regulatory domain F Parlati, T Weber, JA McNew, B Westermann, TH Söllner, JE Rothman Proceedings of the National Academy of Sciences 96 (22), 12565-12570, 1999 | 305 | 1999 |
Functional architecture of an intracellular membrane t-SNARE R Fukuda, JA McNew, T Weber, F Parlati, T Engel, W Nickel, JE Rothman, ... Nature 407 (6801), 198-202, 2000 | 298 | 2000 |
Adeno-associated virus 2 infection requires endocytosis through the CLIC/GEEC pathway M Nonnenmacher, T Weber Cell host & microbe 10 (6), 563-576, 2011 | 258 | 2011 |
Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins TJ Melia, T Weber, JA McNew, LE Fisher, RJ Johnston, F Parlati, ... Journal of Cell Biology 158 (5), 929-940, 2002 | 250 | 2002 |
Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs W Nickel, T Weber, JA McNew, F Parlati, TH Söllner, JE Rothman Proceedings of the National Academy of Sciences 96 (22), 12571-12576, 1999 | 242 | 1999 |
Expressing transgenes that exceed the packaging capacity of adeno-associated virus capsids K Chamberlain, JM Riyad, T Weber Human gene therapy methods 27 (1), 1-12, 2016 | 203 | 2016 |
Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models K Rapti, V Louis-Jeune, E Kohlbrenner, K Ishikawa, D Ladage, ... Molecular Therapy 20 (1), 73-83, 2012 | 203 | 2012 |
The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion JA McNew, T Weber, DM Engelman, TH Söllner, JE Rothman Molecular cell 4 (3), 415-421, 1999 | 203 | 1999 |
Gene therapy for heart failure L Tilemann, K Ishikawa, T Weber, RJ Hajjar Circulation research 110 (5), 777-793, 2012 | 169 | 2012 |
Ceramide as an activator lipid of cathepsin D M Heinrich, M Wickel, S Winoto-Morbach, W Schneider-Brachert, T Weber, ... Cellular Peptidases in Immune Functions and Diseases 2, 305-315, 2002 | 153 | 2002 |
SNAREpins are functionally resistant to disruption by NSF and αSNAP T Weber, F Parlati, JA McNew, RJ Johnston, B Westermann, TH Söllner, ... Journal of Cell Biology 149 (5), 1063-1072, 2000 | 153 | 2000 |
Evidence for H (+)-induced insertion of influenza hemagglutinin HA2 N-terminal segment into viral membrane T Weber, G Paesold, C Galli, R Mischler, G Semenza, J Brunner Journal of Biological Chemistry 269 (28), 18353-18358, 1994 | 135 | 1994 |
Anti-AAV antibodies in AAV gene therapy: current challenges and possible solutions T Weber Frontiers in immunology 12, 658399, 2021 | 131 | 2021 |
Human cardiac gene therapy K Ishikawa, T Weber, RJ Hajjar Circulation research 123 (5), 601-613, 2018 | 113 | 2018 |