Obserwuj
Thomas Weber
Thomas Weber
Spark Therapeutics
Zweryfikowany adres z sparktx.com
Tytuł
Cytowane przez
Cytowane przez
Rok
SNAREpins: minimal machinery for membrane fusion
T Weber, BV Zemelman, JA McNew, B Westermann, M Gmachl, F Parlati, ...
Cell 92 (6), 759-772, 1998
30271998
Cathepsin D targeted by acid sphingomyelinase‐derived ceramide
M Heinrich, M Wickel, W Schneider‐Brachert, C Sandberg, J Gahr, ...
The EMBO journal, 1999
4591999
Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs
WC Tucker, T Weber, ER Chapman
Science 304 (5669), 435-438, 2004
4502004
Pre-existing anti–adeno-associated virus antibodies as a challenge in AAV gene therapy
V Louis Jeune, JA Joergensen, RJ Hajjar, T Weber
Human gene therapy methods 24 (2), 59-67, 2013
3882013
Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors
JA McNew, T Weber, F Parlati, RJ Johnston, TJ Melia, TH Söllner, ...
The Journal of cell biology 150 (1), 105-118, 2000
3842000
Intracellular transport of recombinant adeno-associated virus vectors
M Nonnenmacher, T Weber
Gene therapy 19 (6), 649-658, 2012
3382012
Rapid and efficient fusion of phospholipid vesicles by the α-helical core of a SNARE complex in the absence of an N-terminal regulatory domain
F Parlati, T Weber, JA McNew, B Westermann, TH Söllner, JE Rothman
Proceedings of the National Academy of Sciences 96 (22), 12565-12570, 1999
3051999
Functional architecture of an intracellular membrane t-SNARE
R Fukuda, JA McNew, T Weber, F Parlati, T Engel, W Nickel, JE Rothman, ...
Nature 407 (6801), 198-202, 2000
2982000
Adeno-associated virus 2 infection requires endocytosis through the CLIC/GEEC pathway
M Nonnenmacher, T Weber
Cell host & microbe 10 (6), 563-576, 2011
2582011
Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins
TJ Melia, T Weber, JA McNew, LE Fisher, RJ Johnston, F Parlati, ...
Journal of Cell Biology 158 (5), 929-940, 2002
2502002
Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs
W Nickel, T Weber, JA McNew, F Parlati, TH Söllner, JE Rothman
Proceedings of the National Academy of Sciences 96 (22), 12571-12576, 1999
2421999
Expressing transgenes that exceed the packaging capacity of adeno-associated virus capsids
K Chamberlain, JM Riyad, T Weber
Human gene therapy methods 27 (1), 1-12, 2016
2032016
Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models
K Rapti, V Louis-Jeune, E Kohlbrenner, K Ishikawa, D Ladage, ...
Molecular Therapy 20 (1), 73-83, 2012
2032012
The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion
JA McNew, T Weber, DM Engelman, TH Söllner, JE Rothman
Molecular cell 4 (3), 415-421, 1999
2031999
Gene therapy for heart failure
L Tilemann, K Ishikawa, T Weber, RJ Hajjar
Circulation research 110 (5), 777-793, 2012
1692012
Ceramide as an activator lipid of cathepsin D
M Heinrich, M Wickel, S Winoto-Morbach, W Schneider-Brachert, T Weber, ...
Cellular Peptidases in Immune Functions and Diseases 2, 305-315, 2002
1532002
SNAREpins are functionally resistant to disruption by NSF and αSNAP
T Weber, F Parlati, JA McNew, RJ Johnston, B Westermann, TH Söllner, ...
Journal of Cell Biology 149 (5), 1063-1072, 2000
1532000
Evidence for H (+)-induced insertion of influenza hemagglutinin HA2 N-terminal segment into viral membrane
T Weber, G Paesold, C Galli, R Mischler, G Semenza, J Brunner
Journal of Biological Chemistry 269 (28), 18353-18358, 1994
1351994
Anti-AAV antibodies in AAV gene therapy: current challenges and possible solutions
T Weber
Frontiers in immunology 12, 658399, 2021
1312021
Human cardiac gene therapy
K Ishikawa, T Weber, RJ Hajjar
Circulation research 123 (5), 601-613, 2018
1132018
Nie można teraz wykonać tej operacji. Spróbuj ponownie później.
Prace 1–20