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Manfred Schwaiger
Manfred Schwaiger
Head of Operations, pRED Oncology, F. Hoffman-LaRoche Ltd.
Zweryfikowany adres z roche.com - Strona główna
Tytuł
Cytowane przez
Cytowane przez
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Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies
W Schaefer, JT Regula, M Bähner, J Schanzer, R Croasdale, H Dürr, ...
Proceedings of the National academy of Sciences 108 (27), 11187-11192, 2011
5612011
Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties
C Klein, A Lammens, W Schäfer, G Georges, M Schwaiger, E Mössner, ...
MAbs 5 (1), 22-33, 2013
3922013
Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies
G Niederfellner, A Lammens, O Mundigl, GJ Georges, W Schaefer, ...
Blood, The Journal of the American Society of Hematology 118 (2), 358-367, 2011
3002011
NMR investigation of the multidrug transporter EmrE, an integral membrane protein
M Schwaiger, M Lebendiker, H Yerushalmi, M Coles, A Gröger, ...
European journal of biochemistry 254 (3), 610-619, 1998
1191998
NMR spectroscopy reveals the solution dimerization interface of p53 core domains bound to their consensus DNA
C Klein, E Planker, T Diercks, H Kessler, KP Kunkele, K Lang, S Hansen, ...
Journal of Biological Chemistry 276 (52), 49020-49027, 2001
992001
Cooperative binding of p53 to DNA: regulation by protein–protein interactions through a double salt bridge
A Dehner, C Klein, S Hansen, L Müller, J Buchner, M Schwaiger, ...
Angewandte Chemie International Edition 44 (33), 5247-5251, 2005
692005
Monovalent Antigen Binding Proteins
B Bossenmaier, H Kettenberger, C Klein, KP Kuenkele, JT Regula, ...
US Patent App. 13/406,503, 2012
292012
A Novel Synthesis of Highly Substituted Perhydropyrrolizines, Perhydroindolizines, and Pyrrolidines: Inhibition of the Peptidyl‐Prolyl cis/trans Isomerase (PPIase …
R Siegrist, M Zürcher, C Baumgartner, P Seiler, F Diederich, S Daum, ...
Helvetica chimica acta 90 (2), 217-259, 2007
282007
Dual FC antigen binding proteins
B Bossenmaier, H Kettenberger, C Klein, KP Kuenkele, JT Regula, ...
US Patent 9,982,036, 2018
262018
Response to: monoclonal antibodies targeting CD20
C Klein, A Lammens, W Schäfer, G Georges, M Schwaiger, E Mössner, ...
MAbs 5 (3), 337-338, 2013
162013
Crystal Structure Analysis Reveals That the Novel Type II Anti-CD20 Antibody GA101 Interacts with a Similar Epitope as Rituximab and Ocrelizumab but in a Fundamentally …
GJ Niederfellner, A Lammens, M Schwaiger, G Georges, K Wiechmann, ...
Blood, The Journal of the American Society of Hematology 114 (22), 3726-3726, 2009
162009
Amide derivatives of 3-phenyl-dihydropyrimido [4, 5-d] pyrimidinones, their manufacture and use as pharmaceutical agents
R Engh, H Hertenberger, K Honold, B Masjost, P Rueger, W Schaefer, ...
US Patent 7,655,651, 2010
12*2010
Backbone H-1, C-13 and N-15 resonance assignments for the 25.8 kDa DNA binding domain of the human p63 protein
J Furrer
Journal of Biomolecular NMR 26 (4), 377-378, 2003
122003
DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity
C Sustmann, S Dickopf, JT Regula, H Kettenberger, M Mølhøj, C Gassner, ...
MAbs 11 (8), 1402-1414, 2019
102019
Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties. MAbs. 2013; 5 (1): 22-33
C Klein, A Lammens, W Schäfer, G Georges, M Schwaiger, E Mössner, ...
DOI, 0
10
HSQC-based methyl group selection via gradients in multidimensional NMR spectroscopy of proteins
T Diercks, M Schwaiger, H Kessler
Journal of Magnetic Resonance 130 (2), 335-340, 1998
81998
Monovalent antigen binding proteins
B Bossenmaier, H Kettenberger, C Klein, KP Kuenkele, JT Regula, ...
US Patent 10,611,825, 2020
62020
In vitro folding and characterization of the p53 DNA binding domain
C Klein, F Hesse, A Dehner, RA Engh, M Schwaiger, S Hansen
Walter de Gruyter 385 (1), 95-102, 2004
62004
Kooperative Bindung von p53 an DNA: Regulation durch Protein‐Protein‐Wechselwirkung unter Bildung einer doppelten Salzbrücke
A Dehner, C Klein, S Hansen, L Müller, J Buchner, M Schwaiger, ...
Angewandte Chemie 117 (33), 5381-5386, 2005
52005
Production of a specifically labeled protein in mg quantities for NMR analysis
E Fernholz, A Bartes, H Besir, A Kühlewein, D Mayr, R Schmitt, ...
Cell-Free Protein Expression, 55-60, 2003
32003
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