Serum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection V Bihrer, M Friedrich-Rust, B Kronenberger, N Forestier, J Haupenthal, ... Official journal of the American College of Gastroenterology| ACG 106 (9 …, 2011 | 240 | 2011 |
High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis F Finkelmeier, Ö Canli, A Tal, T Pleli, J Trojan, M Schmidt, ... European journal of cancer 59, 152-159, 2016 | 234 | 2016 |
Serum microRNA-1 and microRNA-122 are prognostic markers in patients with hepatocellular carcinoma V Koeberle, B Kronenberger, T Pleli, J Trojan, E Imelmann, ... European Journal of Cancer 49 (16), 3442-3449, 2013 | 225 | 2013 |
Differential stability of cell-free circulating microRNAs: implications for their utilization as biomarkers V Köberle, T Pleli, C Schmithals, E Augusto Alonso, J Haupenthal, ... PloS one 8 (9), e75184, 2013 | 217 | 2013 |
Inhibition of RNAse A family enzymes prevents degradation and loss of silencing activity of siRNAs in serum J Haupenthal, C Baehr, S Kiermayer, S Zeuzem, A Piiper Biochemical pharmacology 71 (5), 702-710, 2006 | 194 | 2006 |
Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma V Bihrer, O Waidmann, M Friedrich-Rust, N Forestier, S Susser, ... PloS one 6 (10), e26971, 2011 | 171 | 2011 |
Serum microRNA‐122 levels in different groups of patients with chronic hepatitis B virus infection O Waidmann, V Bihrer, T Pleli, H Farnik, A Berger, S Zeuzem, ... Journal of viral hepatitis 19 (2), e58-e65, 2012 | 168 | 2012 |
Proton pump inhibitor treatment is associated with the severity of liver disease and increased mortality in patients with cirrhosis G Dultz, A Piiper, S Zeuzem, B Kronenberger, O Waidmann Alimentary pharmacology & therapeutics 41 (5), 459-466, 2015 | 156 | 2015 |
Epac activation converts cAMP from a proliferative into a differentiation signal in PC12 cells S Kiermayer, RM Biondi, J Imig, G Plotz, J Haupenthal, S Zeuzem, ... Molecular biology of the cell 16 (12), 5639-5648, 2005 | 151 | 2005 |
Macrophage activation is a prognostic parameter for variceal bleeding and overall survival in patients with liver cirrhosis O Waidmann, F Brunner, E Herrmann, S Zeuzem, A Piiper, ... Journal of hepatology 58 (5), 956-961, 2013 | 135 | 2013 |
High serum levels of the interleukin-33 receptor soluble ST2 as a negative prognostic factor in hepatocellular carcinoma D Bergis, V Kassis, A Ranglack, V Koeberle, A Piiper, B Kronenberger, ... Translational oncology 6 (3), 311-318, 2013 | 130 | 2013 |
Allosteric activation of the protein kinase PDK1 with low molecular weight compounds M Engel, V Hindie, LA Lopez‐Garcia, A Stroba, F Schaeffer, I Adrian, ... The EMBO journal 25 (23), 5469-5480, 2006 | 127 | 2006 |
Tumor regression by combination antisense therapy against Plk1 and Bcl-2 R Elez, A Piiper, B Kronenberger, M Kock, M Brendel, E Hermann, ... Oncogene 22 (1), 69-80, 2003 | 122 | 2003 |
Dysregulation of global microRNA expression in splenic marginal zone lymphoma and influence of chronic hepatitis C virus infection J Peveling-Oberhag, G Crisman, A Schmidt, C Döring, M Lucioni, ... Leukemia 26 (7), 1654-1662, 2012 | 121 | 2012 |
Soluble serum CD81 is elevated in patients with chronic hepatitis C and correlates with alanine aminotransferase serum activity MW Welker, D Reichert, S Susser, C Sarrazin, Y Martinez, E Herrmann, ... PloS one 7 (2), e30796, 2012 | 114 | 2012 |
Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth … A Piiper, I Dikic, MP Lutz, J Leser, B Kronenberger, R Elez, H Cramer, ... Journal of biological chemistry 277 (46), 43623-43630, 2002 | 108 | 2002 |
Severe 25‐hydroxyvitamin D deficiency identifies a poor prognosis in patients with hepatocellular carcinoma–a prospective cohort study F Finkelmeier, B Kronenberger, V Köberle, J Bojunga, S Zeuzem, J Trojan, ... Alimentary pharmacology & therapeutics 39 (10), 1204-1212, 2014 | 100 | 2014 |
Serum microRNA-122 predicts survival in patients with liver cirrhosis O Waidmann, V Köberle, F Brunner, S Zeuzem, A Piiper, B Kronenberger Public Library of Science 7 (9), e45652, 2012 | 99 | 2012 |
Cholecystokinin stimulates extracellular signal-regulated kinase through activation of the epidermal growth factor receptor, Yes, and protein kinase C: signal amplification at … A Piiper, R Elez, SJ You, B Kronenberger, S Loitsch, S Roche, S Zeuzem Journal of biological chemistry 278 (9), 7065-7072, 2003 | 91 | 2003 |
Substrate-selective inhibition of protein kinase PDK1 by small compounds that bind to the PIF-pocket allosteric docking site K Busschots, LA Lopez-Garcia, C Lammi, A Stroba, S Zeuzem, A Piiper, ... Chemistry & biology 19 (9), 1152-1163, 2012 | 90 | 2012 |