The DNA damage response: making it safe to play with knives A Ciccia, SJ Elledge Molecular cell 40 (2), 179-204, 2010 | 5201 | 2010 |
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo KL Meerbrey, G Hu, JD Kessler, K Roarty, MZ Li, JE Fang, JI Herschkowitz, ... Proceedings of the National Academy of Sciences 108 (9), 3665-3670, 2011 | 751 | 2011 |
Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM A Ciccia, C Ling, R Coulthard, Z Yan, Y Xue, AR Meetei, EH Laghmani, ... Molecular cell 25 (3), 331-343, 2007 | 420 | 2007 |
Restoration of replication fork stability in BRCA1-and BRCA2-deficient cells by inactivation of SNF2-family fork remodelers A Taglialatela, S Alvarez, G Leuzzi, V Sannino, L Ranjha, JW Huang, ... Molecular cell 68 (2), 414-430. e8, 2017 | 408 | 2017 |
Smarcal1-mediated fork reversal triggers Mre11-dependent degradation of nascent DNA in the absence of Brca2 and stable Rad51 nucleofilaments AM Kolinjivadi, V Sannino, A De Antoni, K Zadorozhny, M Kilkenny, ... Molecular cell 67 (5), 867-881. e7, 2017 | 389 | 2017 |
CRISPR-mediated base editing enables efficient disruption of eukaryotic genes through induction of STOP codons P Billon, EE Bryant, SA Joseph, TS Nambiar, SB Hayward, R Rothstein, ... Molecular cell 67 (6), 1068-1079. e4, 2017 | 386 | 2017 |
Autoantigen discovery with a synthetic human peptidome HB Larman, Z Zhao, U Laserson, MZ Li, A Ciccia, MAM Gakidis, ... Nature biotechnology 29 (6), 535-541, 2011 | 372 | 2011 |
Structural and functional relationships of the XPF/MUS81 family of proteins A Ciccia, N McDonald, SC West Annu. Rev. Biochem. 77 (1), 259-287, 2008 | 356 | 2008 |
Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress A Ciccia, AV Nimonkar, Y Hu, I Hajdu, YJ Achar, L Izhar, SA Petit, ... Molecular cell 47 (3), 396-409, 2012 | 344 | 2012 |
Identification and characterization of the human mus81-eme1 endonuclease A Ciccia, A Constantinou, SC West Journal of Biological Chemistry 278 (27), 25172-25178, 2003 | 278 | 2003 |
Replication fork slowing and reversal upon DNA damage require PCNA polyubiquitination and ZRANB3 DNA translocase activity M Vujanovic, J Krietsch, MC Raso, N Terraneo, R Zellweger, JA Schmid, ... Molecular cell 67 (5), 882-890. e5, 2017 | 256 | 2017 |
FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex SJ Collis, A Ciccia, AJ Deans, Z Hořejší, JS Martin, SL Maslen, JM Skehel, ... Molecular cell 32 (3), 313-324, 2008 | 256 | 2008 |
The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart A Ciccia, AL Bredemeyer, ME Sowa, ME Terret, PV Jallepalli, JW Harper, ... Genes & development 23 (20), 2415-2425, 2009 | 253 | 2009 |
Functional interrogation of DNA damage response variants with base editing screens R Cuella-Martin, SB Hayward, X Fan, X Chen, JW Huang, A Taglialatela, ... Cell 184 (4), 1081-1097. e19, 2021 | 206 | 2021 |
A systematic analysis of factors localized to damaged chromatin reveals PARP-dependent recruitment of transcription factors L Izhar, B Adamson, A Ciccia, J Lewis, L Pontano-Vaites, Y Leng, ... Cell reports 11 (9), 1486-1500, 2015 | 187 | 2015 |
Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells J Abraham, B Lemmers, MP Hande, ME Moynahan, C Chahwan, A Ciccia, ... The EMBO journal, 2003 | 159 | 2003 |
REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps A Taglialatela, G Leuzzi, V Sannino, R Cuella-Martin, JW Huang, ... Molecular cell 81 (19), 4008-4025. e7, 2021 | 147 | 2021 |
CRISPR-based genome editing through the lens of DNA repair TS Nambiar, L Baudrier, P Billon, A Ciccia Molecular cell 82 (2), 348-388, 2022 | 146 | 2022 |
Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant TS Nambiar, P Billon, G Diedenhofen, SB Hayward, A Taglialatela, K Cai, ... Nature Communications 10 (1), 3395, 2019 | 146 | 2019 |
A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability BC O'Connell, B Adamson, JR Lydeard, ME Sowa, A Ciccia, ... Molecular cell 40 (4), 645-657, 2010 | 139 | 2010 |