| Identification of stem cells in small intestine and colon by marker gene Lgr5 N Barker, JH Van Es, J Kuipers, P Kujala, M Van Den Born, M Cozijnsen, ... Nature 449 (7165), 1003-1007, 2007 | 6565 | 2007 |
| Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling W De Lau, N Barker, TY Low, BK Koo, VSW Li, H Teunissen, P Kujala, ... Nature 476 (7360), 293-297, 2011 | 1462 | 2011 |
| Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin HJ Snippert, A Haegebarth, M Kasper, V Jaks, JH van Es, N Barker, ... Science 327 (5971), 1385-1389, 2010 | 914 | 2010 |
| Transcription factor achaete scute-like 2 controls intestinal stem cell fate LG Van Der Flier, ME Van Gijn, P Hatzis, P Kujala, A Haegebarth, ... Cell 136 (5), 903-912, 2009 | 831 | 2009 |
| OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells LG Van der Flier, A Haegebarth, DE Stange, M Van de Wetering, ... Gastroenterology 137 (1), 15-17, 2009 | 615 | 2009 |
| The intestinal Wnt/TCF signature LG Van der Flier, J Sabates–Bellver, I Oving, A Haegebarth, M De Palo, ... Gastroenterology 132 (2), 628-632, 2007 | 579 | 2007 |
| Wnt signaling, lgr5, and stem cells in the intestine and skin A Haegebarth, H Clevers The American journal of pathology 174 (3), 715-721, 2009 | 470 | 2009 |
| Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity K Vriens, S Christen, S Parik, D Broekaert, K Yoshinaga, A Talebi, ... Nature 566 (7744), 403-406, 2019 | 435 | 2019 |
| A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal JH van Es, A Haegebarth, P Kujala, S Itzkovitz, BK Koo, SF Boj, J Korving, ... Molecular and cellular biology 32 (10), 1918-1927, 2012 | 323 | 2012 |
| BAY 80-6946 is a highly selective intravenous PI3K inhibitor with potent p110α and p110δ activities in tumor cell lines and xenograft models N Liu, BR Rowley, CO Bull, C Schneider, A Haegebarth, CA Schatz, ... Molecular cancer therapeutics 12 (11), 2319-2330, 2013 | 288 | 2013 |
| Loss of the tumor suppressor CYLD enhances Wnt/β-catenin signaling through K63-linked ubiquitination of Dvl DVF Tauriello, A Haegebarth, I Kuper, MJ Edelmann, M Henraat, ... Molecular cell 37 (5), 607-619, 2010 | 284 | 2010 |
| Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand SF Boj, JH van Es, M Huch, VSW Li, A José, P Hatzis, M Mokry, ... Cell 151 (7), 1595-1607, 2012 | 266 | 2012 |
| The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies S Christian, C Merz, L Evans, S Gradl, H Seidel, A Friberg, A Eheim, ... Leukemia 33 (10), 2403-2415, 2019 | 191 | 2019 |
| Are metformin doses used in murine cancer models clinically relevant? NS Chandel, D Avizonis, CR Reczek, SE Weinberg, S Menz, R Neuhaus, ... Cell metabolism 23 (4), 569-570, 2016 | 172 | 2016 |
| Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth L Schöckel, A Glasauer, F Basit, K Bitschar, H Truong, G Erdmann, ... Cancer & metabolism 3, 1-16, 2015 | 164 | 2015 |
| Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle SK Radhakrishnan, CS Feliciano, F Najmabadi, A Haegebarth, ... Oncogene 23 (23), 4173-4176, 2004 | 151 | 2004 |
| Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo A Chaturvedi, L Herbst, S Pusch, L Klett, R Goparaju, D Stichel, ... Leukemia 31 (10), 2020-2028, 2017 | 145 | 2017 |
| Dynamics of Lgr6+ progenitor cells in the hair follicle, sebaceous gland, and interfollicular epidermis A Füllgrabe, S Joost, A Are, T Jacob, U Sivan, A Haegebarth, ... Stem cell reports 5 (5), 843-855, 2015 | 116 | 2015 |
| Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine A Haegebarth, W Bie, R Yang, SE Crawford, V Vasioukhin, E Fuchs, ... Molecular and cellular biology 26 (13), 4949-4957, 2006 | 107 | 2006 |
| Metabolic pathway analyses identify proline biosynthesis pathway as a promoter of liver tumorigenesis Z Ding, RE Ericksen, N Escande-Beillard, QY Lee, A Loh, S Denil, ... Journal of hepatology 72 (4), 725-735, 2020 | 102 | 2020 |