| Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies BD Lehmann, JA Bauer, X Chen, ME Sanders, AB Chakravarthy, Y Shyr, ... The Journal of clinical investigation 121 (7), 2750-2767, 2011 | 6248 | 2011 |
| EGFR, p16, HPV Titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer B Kumar, KG Cordell, JS Lee, FP Worden, ME Prince, HH Tran, GT Wolf, ... Journal of clinical oncology 26 (19), 3128-3137, 2008 | 739 | 2008 |
| Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets JM Balko, JM Giltnane, K Wang, LJ Schwarz, CD Young, RS Cook, ... Cancer discovery 4 (2), 232-245, 2014 | 571 | 2014 |
| PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors BD Lehmann, JA Bauer, JM Schafer, CS Pendleton, L Tang, KC Johnson, ... Breast Cancer Research 16, 1-14, 2014 | 390 | 2014 |
| Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer L Formisano, Y Lu, A Servetto, AB Hanker, VM Jansen, JA Bauer, ... Nature communications 10 (1), 1373, 2019 | 349 | 2019 |
| TNBCtype: a subtyping tool for triple-negative breast cancer X Chen, J Li, WH Gray, BD Lehmann, JA Bauer, Y Shyr, JA Pietenpol Cancer informatics 11, CIN. S9983, 2012 | 287 | 2012 |
| Identification of markers of taxane sensitivity using proteomic and genomic analyses of breast tumors from patients receiving neoadjuvant paclitaxel and radiation JA Bauer, AB Chakravarthy, JM Rosenbluth, D Mi, EH Seeley, ... Clinical Cancer Research 16 (2), 681-690, 2010 | 241 | 2010 |
| Kinome-wide RNA interference screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition in ER-positive breast cancer VM Jansen, NE Bhola, JA Bauer, L Formisano, KM Lee, KE Hutchinson, ... Cancer research 77 (9), 2488-2499, 2017 | 235 | 2017 |
| Quantifying drug combination synergy along potency and efficacy axes CT Meyer, DJ Wooten, BB Paudel, J Bauer, KN Hardeman, D Westover, ... Cell systems 8 (2), 97-108. e16, 2019 | 180 | 2019 |
| A novel BH3 mimetic reveals a mitogen-activated protein kinase–dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species M Verhaegen, JA Bauer, C Martín de la Vega, G Wang, KG Wolter, ... Cancer research 66 (23), 11348-11359, 2006 | 173 | 2006 |
| In vitro Effects of the BH3 Mimetic, (−)-Gossypol, on Head and Neck Squamous Cell Carcinoma Cells CL Oliver, JA Bauer, KG Wolter, ML Ubell, A Narayan, KM O’Connell, ... Clinical Cancer Research 10 (22), 7757-7763, 2004 | 170 | 2004 |
| Reversal of cisplatin resistance with a BH3 mimetic, (−)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL JA Bauer, DK Trask, B Kumar, G Los, J Castro, J Shin-Jung Lee, J Chen, ... Molecular cancer therapeutics 4 (7), 1096-1104, 2005 | 161 | 2005 |
| Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer S Shangary, K Ding, S Qiu, Z Nikolovska-Coleska, JA Bauer, M Liu, ... Molecular cancer therapeutics 7 (6), 1533-1542, 2008 | 134 | 2008 |
| SFK/FAK signaling attenuates osimertinib efficacy in both drug-sensitive and drug-resistant models of EGFR-mutant lung cancer E Ichihara, D Westover, CB Meador, Y Yan, JA Bauer, P Lu, F Ye, A Kulick, ... Cancer research 77 (11), 2990-3000, 2017 | 133 | 2017 |
| Preoperative concurrent paclitaxel-radiation in locally advanced breast cancer: pathologic response correlates with five-year overall survival S Adams, AB Chakravarthy, M Donach, D Spicer, S Lymberis, B Singh, ... Breast cancer research and treatment 124, 723-732, 2010 | 100 | 2010 |
| RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells JA Bauer, F Ye, CB Marshall, BD Lehmann, CS Pendleton, Y Shyr, ... Breast Cancer Research 12, 1-16, 2010 | 91 | 2010 |
| Cellular manganese content is developmentally regulated in human dopaminergic neurons KK Kumar, EW Lowe, Jr, AA Aboud, MD Neely, R Redha, JA Bauer, ... Scientific reports 4 (1), 6801, 2014 | 90 | 2014 |
| Comparative study of exome copy number variation estimation tools using array comparative genomic hybridization as control Y Guo, Q Sheng, DC Samuels, B Lehmann, JA Bauer, J Pietenpol, Y Shyr BioMed research international 2013 (1), 915636, 2013 | 77 | 2013 |
| Antagonism of the sodium-potassium ATPase impairs chikungunya virus infection AW Ashbrook, AJ Lentscher, PF Zamora, LA Silva, NA May, JA Bauer, ... MBio 7 (3), 10.1128/mbio. 00693-16, 2016 | 68 | 2016 |
| Targeting MYCN-expressing triple-negative breast cancer with BET and MEK inhibitors JM Schafer, BD Lehmann, PI Gonzalez-Ericsson, CB Marshall, JS Beeler, ... Science translational medicine 12 (534), eaaw8275, 2020 | 66 | 2020 |
Yu ShyrDirector, Vanderbilt Center for Quantitative SciencesZweryfikowany adres z vanderbilt.edu
