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Ruth Roberts
Ruth Roberts
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Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis
R Roberts, J Gallagher, E Spooncer, TD Alien, F Bloomfield, TM Dexter
Nature 332 (6162), 376-378, 1988
10901988
Drug‐induced oxidative stress and toxicity
DG Deavall, EA Martin, JM Horner, R Roberts
Journal of toxicology 2012 (1), 645460, 2012
8642012
PPARα agonist-induced rodent tumors: modes of action and human relevance
JE Klaunig, MA Babich, KP Baetcke, JC Cook, JC Corton, RM David, ...
Critical reviews in toxicology 33 (6), 655-780, 2003
7082003
Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis
RA Roberts, PE Ganey, C Ju, LM Kamendulis, I Rusyn, JE Klaunig
Toxicological Sciences 96 (1), 2-15, 2007
4712007
Nitrative and oxidative stress in toxicology and disease
RA Roberts, DL Laskin, CV Smith, FM Robertson, EMG Allen, JA Doorn, ...
Toxicological sciences 112 (1), 4-16, 2009
3242009
Toxicological and pathophysiological roles of reactive oxygen and nitrogen species
RA Roberts, RA Smith, S Safe, C Szabo, RB Tjalkens, FM Robertson
Toxicology 276 (2), 85-94, 2010
2882010
Induction of heart valve lesions by small-molecule ALK5 inhibitors
MJ Anderton, HR Mellor, A Bell, C Sadler, M Pass, S Powell, SJ Steele, ...
Toxicologic pathology 39 (6), 916-924, 2011
2742011
Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator nafenopin.
AC Bayly, RA Roberts, C Dive
Journal of Cell Biology 125 (1), 197-203, 1994
2461994
Gender differences in drug toxicity
TJ Nicolson, HR Mellor, RRA Roberts
Trends in pharmacological sciences 31 (3), 108-114, 2010
2072010
Cardiotoxicity associated with targeting kinase pathways in cancer
HR Mellor, AR Bell, JP Valentin, RRA Roberts
Toxicological Sciences 120 (1), 14-32, 2011
1822011
Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPAR alpha).
RA Roberts, NH James, NJ Woodyatt, N Macdonald, JD Tugwood
Carcinogenesis 19 (1), 43-48, 1998
1741998
Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease
E Boitier, JC Gautier, R Roberts
Comparative hepatology 2 (1), 3, 2003
1462003
Non-genotoxic hepatocarcinogenesis stimulate DNA synthesis and their withdrawal induces apoptosis, but in different hepatocyte populations
RA Roberts, AR Soames, JH Gill, NH James, EB Wheeldon
Carcinogenesis 16 (8), 1693-1698, 1995
1311995
The peroxisome proliferator (PP) response element upstream of the human acyl CoA oxidase gene is inactive among a sample human population: significance for species differences …
NJ Woodyatt, KG Lambe, KA Myers, JD Tugwood, RA Roberts
Carcinogenesis 20 (3), 369-372, 1999
1301999
AI-based language models powering drug discovery and development
Z Liu, RA Roberts, M Lal-Nag, X Chen, R Huang, W Tong
Drug Discovery Today 26 (11), 2593-2607, 2021
1262021
The role of protein kinase B and mitogen‐activated protein kinase in epidermal growth factor and tumor necrosis factor α–mediated rat hepatocyte survival and apoptosis
RA Roberts, NH James, SC Cosulich
Hepatology 31 (2), 420-427, 2000
1252000
Metabolically inactive 3T3 cells can substitute for marrow stromal cells to promote the proliferation and development of multipotent haemopoietic stem cells
RA Roberts, E Spooncer, EK Parkinson, BI Lord, TD Allen, TM Dexter
Journal of cellular physiology 132 (2), 203-214, 1987
1231987
Toxicogenomics: a 2020 vision
Z Liu, R Huang, R Roberts, W Tong
Trends in pharmacological sciences 40 (2), 92-103, 2019
1212019
Species differences in response to peroxisome proliferators correlate in vitro with induction of DNA synthesis rather than suppression of apoptosis
NH James, RA Roberts
Carcinogenesis 17 (8), 1623-1632, 1996
1191996
Tumour necrosis factor alpha (TNF alpha) suppresses apoptosis and induces DNA synthesis in rodent hepatocytes: a mediator of the hepatocarcinogenicity of peroxisome proliferators?
M Rolfe, NH James, RA Roberts
Carcinogenesis 18 (11), 2277-2280, 1997
1181997
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