Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia PP Zenatti, D Ribeiro, W Li, L Zuurbier, MC Silva, M Paganin, J Tritapoe, ... Nature genetics 43 (10), 932, 2011 | 500 | 2011 |
HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL) J Soulier, E Clappier, JM Cayuela, A Regnault, M García-Peydró, ... Blood 106 (1), 274-286, 2005 | 451 | 2005 |
PHF6 mutations in T-cell acute lymphoblastic leukemia P Van Vlierberghe, T Palomero, H Khiabanian, J Van der Meulen, ... Nature genetics 42 (4), 338, 2010 | 352 | 2010 |
Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development E Martín-Gayo, E Sierra-Filardi, AL Corbí, ML Toribio Blood 115 (26), 5366-5375, 2010 | 265 | 2010 |
CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia S González-García, M García-Peydró, E Martín-Gayo, E Ballestar, ... Journal of Experimental Medicine 206 (4), 779-791, 2009 | 180 | 2009 |
Identification of a common developmental pathway for thymic natural killer cells and dendritic cells C Márquez, C Trigueros, JM Franco, AR Ramiro, YR Carrasco, ... Blood 91 (8), 2760-2771, 1998 | 152 | 1998 |
lnterleukin-2-dependent autocrine proliferation in T-cell development ML Toribio, JC Gutiérrez-Ramos, L Pezzi, MAR Marcos, C Martínez-A Nature 342 (6245), 82, 1989 | 132 | 1989 |
Fratricide-resistant CD1a-specific CAR T-cells for the treatment of cortical T-cell acute lymphoblastic leukemia D Sánchez-Martínez, ML Baroni, F Gutierrez-Agüera, H Roca-Ho, ... Blood, blood-2018-10-882944, 2019 | 123 | 2019 |
The development of T and non-T cell lineages from CD34+ human thymic precursors can be traced by the differential expression of CD44. C Marquez, C Trigueros, E Fernandez, ML Toribio Journal of Experimental Medicine 181 (2), 475-483, 1995 | 122 | 1995 |
Maintenance of immune tolerance by Foxp3+ regulatory T cells requires CD69 expression JR Cortés, R Sánchez-Díaz, ER Bovolenta, O Barreiro, S Lasarte, ... Journal of autoimmunity 55, 51-62, 2014 | 121 | 2014 |
The DC-SIGN–related lectin LSECtin mediates antigen capture and pathogen binding by human myeloid cells A Dominguez-Soto, L Aragoneses-Fenoll, E Martin-Gayo, ... Blood 109 (12), 5337-5345, 2007 | 118 | 2007 |
Sustained Notch1 signaling instructs the earliest human intrathymic precursors to adopt a γδ T-cell fate in fetal thymus organ culture M García-Peydró, VG de Yébenes, ML Toribio Blood 102 (7), 2444-2451, 2003 | 105 | 2003 |
The differentiation stage of p53-Rb-deficient bone marrow mesenchymal stem cells imposes the phenotype of in vivo sarcoma development R Rubio, I Gutierrez-Aranda, AI Saez-Castillo, A Labarga, M Rosu-Myles, ... Oncogene 32 (41), 4970, 2013 | 102 | 2013 |
SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis P Esteve, A Sandonìs, M Cardozo, J Malapeira, C Ibañez, I Crespo, ... Nature neuroscience 14 (5), 562, 2011 | 102 | 2011 |
Notch1 and IL-7 receptor interplay maintains proliferation of human thymic progenitors while suppressing non-T cell fates M García-Peydró, VG de Yébenes, ML Toribio The Journal of Immunology 177 (6), 3711-3720, 2006 | 97 | 2006 |
Establishment and characterization of cloned human thymic epithelial cell lines. Analysis of adhesion molecule expression and cytokine production E Fernandez, A Vicente, A Zapata, B Brera, JJ Lozano, C Martinez, ... Blood 83 (11), 3245-3254, 1994 | 96 | 1994 |
Regulation of pre-T cell receptor (pT alpha-TCR beta) gene expression during human thymic development. AR Ramiro, C Trigueros, C Márquez, JL San Millán, ML Toribio Journal of Experimental Medicine 184 (2), 519-530, 1996 | 93 | 1996 |
Interleukin 2 promotes growth and cytolytic activity in human T3+ 4-8-thymocytes A De La Hera, ML Toribio, C Marquez, C Martinez Proceedings of the National Academy of Sciences 82 (18), 6268-6271, 1985 | 85 | 1985 |
Notch-regulated miR-223 targets the aryl hydrocarbon receptor pathway and increases cytokine production in macrophages from rheumatoid arthritis patients J Ogando, M Tardáguila, A Díaz-Alderete, A Usategui, V Miranda-Ramos, ... Scientific reports 6, 20223, 2016 | 80 | 2016 |
Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular organs AE Rodríguez-Fraticelli, J Bagwell, M Bosch-Fortea, G Boncompain, ... Nature cell biology 17 (3), 241, 2015 | 76 | 2015 |