CRISPR inversion of CTCF sites alters genome topology and enhancer/promoter function Y Guo, Q Xu, D Canzio, J Shou, J Li, DU Gorkin, I Jung, H Wu, Y Zhai, ... Cell 162 (4), 900-910, 2015 | 1077 | 2015 |
A striking organization of a large family of human neural cadherin-like cell adhesion genes Q Wu, T Maniatis Cell 97 (6), 779-790, 1999 | 887 | 1999 |
Promoter choice determines splice site selection in protocadherin α and γ pre-mRNA splicing B Tasic, CE Nabholz, KK Baldwin, Y Kim, EH Rueckert, SA Ribich, ... Molecular cell 10 (1), 21-33, 2002 | 343 | 2002 |
Comparative DNA sequence analysis of mouse and human protocadherin gene clusters Q Wu, T Zhang, JF Cheng, Y Kim, J Grimwood, J Schmutz, M Dickson, ... Genome research 11 (3), 389-404, 2001 | 317 | 2001 |
CTCF/cohesin-mediated DNA looping is required for protocadherin α promoter choice Y Guo, K Monahan, H Wu, J Gertz, KE Varley, W Li, RM Myers, T Maniatis, ... Proceedings of the National Academy of Sciences 109 (51), 21081-21086, 2012 | 298 | 2012 |
AT-AC pre-mRNA splicing mechanisms and conservation of minor introns in voltage-gated ion channel genes Q Wu, AR Krainer Molecular and cellular biology 19 (5), 3225-3236, 1999 | 195 | 1999 |
Precise and predictable CRISPR chromosomal rearrangements reveal principles of Cas9-mediated nucleotide insertion J Shou, J Li, Y Liu, Q Wu Molecular cell 71 (4), 498-509. e4, 2018 | 194 | 2018 |
Multiple variable first exons: a mechanism for cell-and tissue-specific gene regulation T Zhang, P Haws, Q Wu Genome research 14 (1), 79-89, 2004 | 189 | 2004 |
A protocol for constructing gene targeting vectors: generating knockout mice for the cadherin family and beyond S Wu, G Ying, Q Wu, MR Capecchi Nature protocols 3 (6), 1056-1076, 2008 | 172 | 2008 |
Toward simpler and faster genome-wide mutagenesis in mice S Wu, G Ying, Q Wu, MR Capecchi Nature genetics 39 (7), 922-930, 2007 | 170 | 2007 |
Efficient inversions and duplications of mammalian regulatory DNA elements and gene clusters by CRISPR/Cas9 J Li, J Shou, Y Guo, Y Tang, Y Wu, Z Jia, Y Zhai, Z Chen, Q Xu, Q Wu Journal of molecular cell biology 7 (4), 284-298, 2015 | 165 | 2015 |
Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes Q Wu, T Maniatis Proceedings of the National Academy of Sciences 97 (7), 3124-3129, 2000 | 160 | 2000 |
Protocadherin clusters and cell adhesion kinase regulate dendrite complexity through Rho GTPase L Suo, H Lu, G Ying, MR Capecchi, Q Wu Journal of molecular cell biology 4 (6), 362-376, 2012 | 155 | 2012 |
Pcdhαc2 is required for axonal tiling and assembly of serotonergic circuitries in mice WV Chen, CL Nwakeze, CA Denny, S O’Keeffe, MA Rieger, ... Science 356 (6336), 406-411, 2017 | 149 | 2017 |
Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites M Yin, J Wang, M Wang, X Li, M Zhang, Q Wu, Y Wang Cell research 27 (11), 1365-1377, 2017 | 116 | 2017 |
EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins U Pohl, JS Smith, I Tachibana, K Ueki, HK Lee, S Ramaswamy, Q Wu, ... Genomics 63 (2), 255-262, 2000 | 112 | 2000 |
U1-mediated exon definition interactions between AT-AC and GT-AG introns Q Wu, AR Krainer Science 274 (5289), 1005-1008, 1996 | 109 | 1996 |
Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes Q Wu Genetics 169 (4), 2179-2188, 2005 | 100 | 2005 |
Splicing of a divergent subclass of AT-AC introns requires the major spliceosomal snRNAs Q Wu, AR Krainer RNA-CAMBRIDGE- 3, 586-601, 1997 | 94 | 1997 |
Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection Z Jia, J Li, X Ge, Y Wu, Y Guo, Q Wu Genome biology 21, 1-24, 2020 | 78 | 2020 |