| A global reference for human genetic variation 1000 Genomes Project Consortium Nature 526 (7571), 68, 2015 | 16610 | 2015 |
| An integrated map of genetic variation from 1,092 human genomes 1000 Genomes Project Consortium Nature 491 (7422), 56, 2012 | 8500 | 2012 |
| Analyzing and interpreting genome data at the network level with ConsensusPathDB R Herwig, C Hardt, M Lienhard, A Kamburov Nature protocols 11 (10), 1889-1907, 2016 | 449 | 2016 |
| DMSO induces drastic changes in human cellular processes and epigenetic landscape in vitro M Verheijen, M Lienhard, Y Schrooders, O Clayton, R Nudischer, ... Scientific reports 9 (1), 4641, 2019 | 399 | 2019 |
| MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments M Lienhard, C Grimm, M Morkel, R Herwig, L Chavez Bioinformatics 30 (2), 284-286, 2014 | 348 | 2014 |
| An integrated map of genetic variation from 1,092 human genomes 1000 Genomes Project Consortium Corresponding Author McVean Gil A. mcvean ... Nature 491 (7422), 56-65, 2012 | 286 | 2012 |
| Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility G Seumois, L Chavez, A Gerasimova, M Lienhard, N Omran, L Kalinke, ... Nature immunology 15 (8), 777-788, 2014 | 214 | 2014 |
| Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ... Nature 553 (7686), 101-105, 2018 | 213 | 2018 |
| The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine JP Etchegaray, L Chavez, Y Huang, KN Ross, J Choi, B Martinez-Pastor, ... Nature cell biology 17 (5), 545-557, 2015 | 173 | 2015 |
| Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis J Kang, M Lienhard, WA Pastor, A Chawla, M Novotny, A Tsagaratou, ... Proceedings of the National Academy of Sciences 112 (31), E4236-E4245, 2015 | 131 | 2015 |
| The digital bee brain: integrating and managing neurons in a common 3D reference system J Rybak, A Kuß, H Lamecker, S Zachow, HC Hege, M Lienhard, J Singer, ... Frontiers in systems neuroscience 4, 30, 2010 | 111 | 2010 |
| Systematic assessment of long-read RNA-seq methods for transcript identification and quantification FJ Pardo-Palacios, D Wang, F Reese, M Diekhans, S Carbonell-Sala, ... Nature methods 21 (7), 1349-1363, 2024 | 101 | 2024 |
| RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo [a] pyrene J van Delft, S Gaj, M Lienhard, MW Albrecht, A Kirpiy, K Brauers, ... Toxicological sciences 130 (2), 427-439, 2012 | 76 | 2012 |
| Crowdsourced mapping of unexplored target space of kinase inhibitors A Cichońska, B Ravikumar, RJ Allaway, F Wan, S Park, O Isayev, S Li, ... Nature communications 12 (1), 3307, 2021 | 75 | 2021 |
| Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies D Thomalla, L Beckmann, C Grimm, M Oliverio, L Meder, CD Herling, ... Blood, The Journal of the American Society of Hematology 140 (20), 2113-2126, 2022 | 70 | 2022 |
| QSEA—modelling of genome-wide DNA methylation from sequencing enrichment experiments M Lienhard, S Grasse, J Rolff, S Frese, U Schirmer, M Becker, S Börno, ... Nucleic acids research 45 (6), e44-e44, 2017 | 57 | 2017 |
| DNA–methylome analysis of mouse intestinal adenoma identifies a tumour-specific signature that is partly conserved in human colon cancer C Grimm, L Chavez, M Vilardell, AL Farrall, S Tierling, JW Böhm, P Grote, ... PLoS genetics 9 (2), e1003250, 2013 | 56 | 2013 |
| Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance S Grasse, M Lienhard, S Frese, M Kerick, A Steinbach, C Grimm, ... Genome medicine 10, 1-16, 2018 | 47 | 2018 |
| Network integration and modelling of dynamic drug responses at multi-omics levels N Selevsek, F Caiment, R Nudischer, H Gmuender, I Agarkova, ... Communications biology 3 (1), 573, 2020 | 38 | 2020 |
| IsoTools: a flexible workflow for long-read transcriptome sequencing analysis M Lienhard, T van den Beucken, B Timmermann, M Hochradel, S Boerno, ... Bioinformatics 39 (6), btad364, 2023 | 19 | 2023 |
Ralf HerwigGroup Leader, Max Planck Institute for molecular Genetics, BerlinVerifisert e-postadresse på molgen.mpg.de