3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets A Birmingham, EM Anderson, A Reynolds, D Ilsley-Tyree, D Leake, ... Nature methods 3 (3), 199-204, 2006 | 1212 | 2006 |
Off-target effects by siRNA can induce toxic phenotype Y Fedorov, EM Anderson, A Birmingham, A Reynolds, J Karpilow, ... Rna 12 (7), 1188-1196, 2006 | 686 | 2006 |
Induction of the interferon response by siRNA is cell type–and duplex length–dependent A Reynolds, EM Anderson, A Vermeulen, Y Fedorov, K Robinson, ... Rna 12 (6), 988-993, 2006 | 451 | 2006 |
ERK1/2 is required for myoblast proliferation but is dispensable for muscle gene expression and cell fusion NC Jones, YV Fedorov, RS Rosenthal, BB Olwin Journal of cellular physiology 186 (1), 104-115, 2001 | 338 | 2001 |
The p38α/β MAPK functions as a molecular switch to activate the quiescent satellite cell NC Jones, KJ Tyner, L Nibarger, HM Stanley, DDW Cornelison, ... The Journal of cell biology 169 (1), 105-116, 2005 | 335 | 2005 |
Coordination of satellite cell activation and self-renewal by Par-complex-dependent asymmetric activation of p38α/β MAPK A Troy, AB Cadwallader, Y Fedorov, K Tyner, KK Tanaka, BB Olwin Cell stem cell 11 (4), 541-553, 2012 | 311 | 2012 |
Functional profiling reveals critical role for miRNA in differentiation of human mesenchymal stem cells A Schoolmeesters, T Eklund, D Leake, A Vermeulen, Q Smith, ... PloS one 4 (5), e5605, 2009 | 233 | 2009 |
Modified polynucleotides for reducing off-target effects in RNA interference D Leake, A Reynolds, A Khvorova, W Marshall, PS Linsley US Patent 7,595,387, 2009 | 224 | 2009 |
Accumulation of 8, 9-unsaturated sterols drives oligodendrocyte formation and remyelination Z Hubler, D Allimuthu, I Bederman, MS Elitt, M Madhavan, KC Allan, ... Nature 560 (7718), 372-376, 2018 | 205 | 2018 |
Experimental validation of the importance of seed complement frequency to siRNA specificity EM Anderson, A Birmingham, S Baskerville, A Reynolds, E Maksimova, ... Rna 14 (5), 853-861, 2008 | 186 | 2008 |
Different delivery methods—different expression profiles Y Fedorov, A King, E Anderson, J Karpilow, D Ilsley, W Marshall, ... Nature methods 2 (4), 241-241, 2005 | 100 | 2005 |
Assessment of Cr (VI)-induced cytotoxicity and genotoxicity using high content analysis CM Thompson, Y Fedorov, DD Brown, M Suh, DM Proctor, L Kuriakose, ... Public Library of Science 7 (8), e42720, 2012 | 81 | 2012 |
Modified polynucleotides for use in rna interference D Leake, A Reynolds, A Khvorova, W Marshall, Y Federov, K Nichols | 74 | 2004 |
Regulation of myogenesis by fibroblast growth factors requires beta-gamma subunits of pertussis toxin-sensitive G proteins YV Fedorov, NC Jones, BB Olwin Molecular and cellular biology 18 (10), 5780-5787, 1998 | 73 | 1998 |
SNP discriminatory siRNA Y Fedorov, A Reynolds, A Khvorova US Patent App. 11/043,637, 2005 | 54 | 2005 |
Modified polynucleotides for use in rna interference D Leake, A Reynolds, A Khvorova, W Marshall, Y Fedorov, K Nichols US Patent App. 10/551,350, 2007 | 49 | 2007 |
Stabilized siRNAs as transfection controls and silencing reagents D Leake, A Khvorova, Y Fedorov, M Delaney, B Robertson, E Anderson, ... US Patent App. 11/051,195, 2007 | 48 | 2007 |
Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma I Bayles, M Krajewska, WD Pontius, A Saiakhova, JJ Morrow, C Bartels, ... The Journal of Clinical Investigation 129 (10), 4377-4392, 2019 | 37 | 2019 |
Oncogenic Ras-induced proliferation requires autocrine fibroblast growth factor 2 signaling in skeletal muscle cells YV Fedorov, RS Rosenthal, BB Olwin The Journal of cell biology 152 (6), 1301-1306, 2001 | 34 | 2001 |
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington’s disease D Hu, X Sun, A Magpusao, Y Fedorov, M Thompson, B Wang, K Lundberg, ... Nature communications 12 (1), 5305, 2021 | 32 | 2021 |