Mucin glycans attenuate the virulence of Pseudomonas aeruginosa in infection KM Wheeler, G Cárcamo-Oyarce, BS Turner, S Dellos-Nolan, JY Co, ... Nature microbiology 4 (12), 2146-2154, 2019 | 218 | 2019 |
Tn and sialyl‐Tn antigens, aberrant O‐glycomics as human disease markers T Ju, Y Wang, RP Aryal, SD Lehoux, X Ding, MR Kudelka, C Cutler, ... PROTEOMICS–Clinical Applications 7 (9-10), 618-631, 2013 | 211 | 2013 |
Generation of fully functional hepatocyte-like organoids from human induced pluripotent stem cells mixed with Endothelial Cells G Pettinato, S Lehoux, R Ramanathan, MM Salem, LX He, O Muse, ... Scientific reports 9 (1), 8920, 2019 | 148 | 2019 |
PDX-derived organoids model in vivo drug response and secrete biomarkers L Huang, B Bockorny, I Paul, D Akshinthala, PO Frappart, O Gandarilla, ... JCI insight 5 (21), e135544, 2020 | 97 | 2020 |
IL-6 and IL-8 increase the expression of glycosyltransferases and sulfotransferases involved in the biosynthesis of sialylated and/or sulfated Lewisx epitopes in the … S Groux-Degroote, MA Krzewinski-Recchi, A Cazet, A Vincent, S Lehoux, ... Biochemical Journal 410 (1), 213-223, 2008 | 91 | 2008 |
GD3 synthase overexpression enhances proliferation and migration of MDA-MB-231 breast cancer cells A Cazet, S Groux-Degroote, B Teylaert, KM Kwon, S Lehoux, ... De Gruyter 390 (7), 601-609, 2009 | 81 | 2009 |
Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues SE Williams, M Noel, S Lehoux, M Cetinbas, RJ Xavier, RI Sadreyev, ... Nature communications 13 (1), 275, 2022 | 79 | 2022 |
Mucin glycans signal through the sensor kinase RetS to inhibit virulence-associated traits in Pseudomonas aeruginosa BX Wang, KM Wheeler, KC Cady, S Lehoux, RD Cummings, MT Laub, ... Current Biology 31 (1), 90-102. e7, 2021 | 76 | 2021 |
N-Glycosylation affects the stability and barrier function of the MUC16 mucin T Taniguchi, AM Woodward, P Magnelli, NM McColgan, S Lehoux, ... Journal of Biological Chemistry 292 (26), 11079-11090, 2017 | 72 | 2017 |
The schizophrenia risk locus in SLC39A8 alters brain metal transport and plasma glycosylation RG Mealer, BG Jenkins, CY Chen, MJ Daly, T Ge, S Lehoux, T Marquardt, ... Scientific Reports 10 (1), 13162, 2020 | 67 | 2020 |
Epigenetic silencing of the chaperone Cosmc in human leukocytes expressing tn antigen R Mi, L Song, Y Wang, X Ding, J Zeng, S Lehoux, RP Aryal, J Wang, ... Journal of Biological Chemistry 287 (49), 41523-41533, 2012 | 67 | 2012 |
Glycosylation of Zika virus is important in host–virus interaction and pathogenic potential NK Routhu, SD Lehoux, EA Rouse, MRM Bidokhti, LB Giron, A Anzurez, ... International journal of molecular sciences 20 (20), 5206, 2019 | 53 | 2019 |
Mucin O-glycans are natural inhibitors of Candida albicans pathogenicity J Takagi, K Aoki, BS Turner, S Lamont, S Lehoux, N Kavanaugh, M Gulati, ... Nature chemical biology 18 (7), 762-773, 2022 | 50 | 2022 |
Identification of Tn antigen O-GalNAc-expressing glycoproteins in human carcinomas using novel anti-Tn recombinant antibodies Y Matsumoto, MR Kudelka, MS Hanes, S Lehoux, S Dutta, MB Jones, ... Glycobiology 30 (5), 282-300, 2020 | 49 | 2020 |
Aberrantly glycosylated IgG elicits pathogenic signaling in podocytes and signifies lupus nephritis R Bhargava, S Lehoux, K Maeda, MG Tsokos, S Krishfield, L Ellezian, ... JCI insight 6 (9), e147789, 2021 | 47 | 2021 |
Mechanisms underlying the cardiometabolic protective effect of walnut consumption in obese people: a cross‐over, randomized, double‐blind, controlled inpatient physiology study D Tuccinardi, OM Farr, J Upadhyay, SM Oussaada, MI Klapa, M Candela, ... Diabetes, Obesity and Metabolism 21 (9), 2086-2095, 2019 | 46 | 2019 |
Transcriptional regulation of the human ST6GAL2 gene in cerebral cortex and neuronal cells S Lehoux, S Groux-Degroote, A Cazet, CM Dhaenens, CA Maurage, ... Glycoconjugate journal 27, 99-114, 2010 | 46 | 2010 |
Identification of distinct glycoforms of IgA1 in plasma from patients with immunoglobulin A (IgA) nephropathy and healthy individuals S Lehoux, R Mi, RP Aryal, Y Wang, TBGS Katrine, H Clausen, I van Die, ... Molecular & Cellular Proteomics 13 (11), 3097-3113, 2014 | 39 | 2014 |
Regulation of neutrophil function by selective targeting of glycan epitopes expressed on the integrin CD11b/CD18 M Kelm, S Lehoux, V Azcutia, RD Cummings, A Nusrat, CA Parkos, ... The FASEB Journal 34 (2), 2326-2343, 2020 | 37 | 2020 |
Cosmc controls B cell homing J Zeng, M Eljalby, RP Aryal, S Lehoux, K Stavenhagen, MR Kudelka, ... Nature Communications 11 (1), 3990, 2020 | 27 | 2020 |