Christopher Liddle

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Michael DownesSenior Staff Scientist, Salk InsitituteVerifisert e-postadresse på salk.edu
Ronald M EvansProfessor, Salk InstituteVerifisert e-postadresse på salk.edu
Jacob GeorgeUniversity of Sydney, Westmead Millennium Institute, Westmead Hospital, University of QueenslandVerifisert e-postadresse på sydney.edu.au
Martin WeltmanAssociate Professor of Medicine, Sydney Medical SchoolVerifisert e-postadresse på wahs.nsw.gov.au
Alan R SaltielUCSDVerifisert e-postadresse på ucsd.edu
Maryam AhmadianThe Salk Institute for Biological StudiesVerifisert e-postadresse på salk.edu
Eiji YoshiharaLundquist Institute at Harbor-UCLA Medical Center/UCLA/Salk Institute/Kyoto UniversityVerifisert e-postadresse på lundquist.org
Stephen ClarkeProfessor of Medicine, University of Sydney and Medical Oncologist, RNSH and Genesis CareVerifisert e-postadresse på sydney.edu.au
Ning DingGenentechVerifisert e-postadresse på gene.com
Mara ShermanOregon Health & Science UniversityVerifisert e-postadresse på ohsu.edu
David BoothUniversity of SydneyVerifisert e-postadresse på sydney.edu.au
Howard GurneyMacquarie University, Faculty of Medicine and Health SciencesVerifisert e-postadresse på mq.edu.au
Weiwei FanSalk Institute for Biological StudiesVerifisert e-postadresse på salk.edu
Jerrold OlefskyUniversity of California San DiegoVerifisert e-postadresse på ucsd.edu
Mark DouglasUniversity of Sydney at Westmead HospitalVerifisert e-postadresse på sydney.edu.au
Grant ParnellThe Westmead Institute for Medical Research, The University of SydneyVerifisert e-postadresse på sydney.edu.au
Junichiro SonodaAmgenVerifisert e-postadresse på amgen.com
Jenny GuntonWestmead Institute of Medical Research, WIMR, University of SydneyVerifisert e-postadresse på sydney.edu.au
A/Prof David van der PoortenUniversity of Sydney at Westmead HospitalVerifisert e-postadresse på sydney.edu.au
Johan W. JonkerProfessor, University Medical Center GroningenVerifisert e-postadresse på umcg.nl

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Christopher Liddle

Emeritus Professor of Clinical Pharmacology and Hepatology, University of Sydney

Verifisert e-postadresse på sydney.edu.au - Startside

gene regulation bile acids nuclear receptors drug metabolism bioinformatics


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PPARγ signaling and metabolism: the good, the bad and the future M Ahmadian, JM Suh, N Hah, C Liddle, AR Atkins, M Downes, RM Evans Nature medicine 19 (5), 557-566, 2013	2192	2013
NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome S Chitturi, S Abeygunasekera, GC Farrell, J Holmes-Walker, JM Hui, ... Hepatology 35 (2), 373-379, 2002	1562	2002
Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β H Cho, X Zhao, M Hatori, RT Yu, GD Barish, MT Lam, LW Chong, ... Nature 485 (7396), 123-127, 2012	1156	2012
Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy MH Sherman, TY Ruth, DD Engle, N Ding, AR Atkins, H Tiriac, ... Cell 159 (1), 80-93, 2014	1129	2014
Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands LB Moore, DJ Parks, SA Jones, RK Bledsoe, TG Consler, JB Stimmel, ... Journal of Biological Chemistry 275 (20), 15122-15127, 2000	1003	2000
The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module B Goodwin, E Hodgson, C Liddle Molecular pharmacology 56 (6), 1329-1339, 1999	825	1999
Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis MD Weltman, GC Farrell, P Hall, M Ingelman-Sundberg, C Liddle Hepatology 27 (1), 128-133, 1998	805	1998
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance S Fang, JM Suh, SM Reilly, E Yu, O Osborn, D Lackey, E Yoshihara, ... Nature medicine 21 (2), 159-165, 2015	781	2015
A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response N Ding, TY Ruth, N Subramaniam, MH Sherman, C Wilson, R Rao, ... Cell 153 (3), 601-613, 2013	670	2013
Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: a manifestation of lipotoxicity? S Chitturi, G Farrell, L Frost, A Kriketos, R Lin, C Liddle, D Samarasinghe, ... Hepatology 36 (2), 403-409, 2002	580	2002
Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation MD Weltman, GC Farrell, C Liddle Gastroenterology 111 (6), 1645-1653, 1996	514	1996
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice SM Reilly, SH Chiang, SJ Decker, L Chang, M Uhm, MJ Larsen, JR Rubin, ... Nature medicine 19 (3), 313-321, 2013	471	2013
Regulation of drug-metabolizing enzymes and transporters in infection, inflammation, and cancer ET Morgan, KB Goralski, M Piquette-Miller, KW Renton, GR Robertson, ... Drug Metabolism and Disposition 36 (2), 205-216, 2008	449	2008
Pre-translational regulation of cytochrome P450 genes is responsible for disease-specific changes of individual P450 enzymes among patients with cirrhosis J George, C Liddle, M Murray, K Byth, GC Farrell Biochemical pharmacology 49 (7), 873-881, 1995	390	1995
FXR regulates intestinal cancer stem cell proliferation T Fu, S Coulter, E Yoshihara, TG Oh, S Fang, F Cayabyab, Q Zhu, ... Cell 176 (5), 1098-1112. e18, 2019	387	2019
Depletion of fat-resident T_reg cells prevents age-associated insulin resistance SP Bapat, J Myoung Suh, S Fang, S Liu, Y Zhang, A Cheng, C Zhou, ... Nature 528 (7580), 137-141, 2015	337	2015
Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes NH Uhlenhaut, GD Barish, TY Ruth, M Downes, M Karunasiri, C Liddle, ... Molecular cell 49 (1), 158-171, 2013	311	2013
Transcriptional regulation of the human CYP3A4gene by the constitutive androstane receptor B Goodwin, E Hodgson, DJ D'Costa, GR Robertson, C Liddle Molecular pharmacology 62 (2), 359-365, 2002	310	2002
Lean NAFLD: a distinct entity shaped by differential metabolic adaptation F Chen, S Esmaili, GB Rogers, E Bugianesi, S Petta, G Marchesini, ... Hepatology 71 (4), 1213-1227, 2020	308	2020
HFE mutations, hepatic iron, and fibrosis: ethnic‐specific association of NASH with C282Y but not with fibrotic severity S Chitturi, M Weltman, GC Farrell, D McDonald, C Liddle, ... Hepatology 36 (1), 142-149, 2002	296	2002

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