Sokol V. Todi

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Henry Paulsonneurology, university of michiganVerifisert e-postadresse på umich.edu
Wei-Ling TsouResearch Assistant Professor, Department of Pharmacology Wayne State University School of MedicineVerifisert e-postadresse på wayne.edu
Jessica BlountPost-Doc, Wayne State University School of MedicineVerifisert e-postadresse på med.wayne.edu
Matt scaglioneDuke UniversityVerifisert e-postadresse på duke.edu
Daniel F. EberlProfessor of Biology, University of IowaVerifisert e-postadresse på uiowa.edu
Alyson SujkowskiWayne State University School of MedicineVerifisert e-postadresse på wayne.edu
Junmin Peng, Ph.D.St. Jude Children's Research HospitalVerifisert e-postadresse på stjude.org
Aislinn WilliamsAssistant Professor of Psychiatry, University of IowaVerifisert e-postadresse på uiowa.edu
Aloke K DuttaWayne State University, Detroit, MI 48202Verifisert e-postadresse på wayne.edu
Dan LuoScientist II, University of KentuckyVerifisert e-postadresse på uky.edu
venkatesha basrurAssociate Research Scientist, University of MichiganVerifisert e-postadresse på med.umich.edu
Gemma MarfanyProfessor of Genetics, Universitat de BarcelonaVerifisert e-postadresse på ub.edu
Deepthi YedlapudiBoston University School of MedicineVerifisert e-postadresse på bu.edu
Josef FrankeInstructor, Creighton UniversityVerifisert e-postadresse på creighton.edu
Grace Boekhoff-FalkCell and Regenerative Biology, UW-Madison School of Medicine and Public HealthVerifisert e-postadresse på wisc.edu
Ezgi KaracaAssistant Professor, Izmir Biomedicine and Genome Center & DEUVerifisert e-postadresse på ibg.edu.tr
Alexandre M.J.J. BonvinUtrecht universityVerifisert e-postadresse på uu.nl
Mário Nôro LaçoPh.D. student, Center for Neuroscience and Cell Biology of CoimbraVerifisert e-postadresse på cnc.uc.pt
Magdalena IvanovaDepartment of Neurology, University of MichiganVerifisert e-postadresse på umich.edu
Annalisa PastoreESRF

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Sokol V. Todi

Wayne State University School of Medicine

Verifisert e-postadresse på wayne.edu

Neurodegeneration Ubiquitin Protein Quality Control Deubiquitinases Polyglutamine Diseases


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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹ DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021	11021	2021
The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains BJ Winborn, SM Travis, SV Todi, KM Scaglione, P Xu, AJ Williams, ... Journal of Biological Chemistry 283 (39), 26436-26443, 2008	336	2008
Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin‐3 SV Todi, BJ Winborn, KM Scaglione, JR Blount, SM Travis, HL Paulson The EMBO journal 28 (4), 372-382, 2009	225	2009
Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP KM Scaglione, E Zavodszky, SV Todi, S Patury, P Xu, ... Molecular cell 43 (4), 599-612, 2011	195	2011
Drosophila KAP interacts with the kinesin II motor subunit KLP64D to assemble chordotonal sensory cilia, but not sperm tails R Sarpal, SV Todi, E Sivan-Loukianova, S Shirolikar, N Subramanian, ... Current biology 13 (19), 1687-1696, 2003	185	2003
Balancing act: deubiquitinating enzymes in the nervous system SV Todi, HL Paulson Trends in neurosciences 34 (7), 370-382, 2011	166	2011
Anatomical and molecular design of the Drosophila antenna as a flagellar auditory organ SV Todi, Y Sharma, DF Eberl Microscopy research and technique 63 (6), 388-399, 2004	129	2004
The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates KM Scaglione, V Basrur, NS Ashraf, JR Konen, KSJ Elenitoba-Johnson, ... Journal of Biological Chemistry 288 (26), 18784-18788, 2013	120	2013
Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117 SV Todi, KM Scaglione, JR Blount, V Basrur, KP Conlon, A Pastore, ... Journal of Biological Chemistry 285 (50), 39303-39313, 2010	120	2010
Myosin VIIA defects, which underlie the Usher 1B syndrome in humans, lead to deafness in Drosophila SV Todi, JD Franke, DP Kiehart, DF Eberl Current Biology 15 (9), 862-868, 2005	104	2005
An optimal ubiquitin-proteasome pathway in the nervous system: the role of deubiquitinating enzymes G Ristic, WL Tsou, SV Todi Frontiers in molecular neuroscience 7, 72, 2014	102	2014
The protective role of exercise against age-related neurodegeneration A Sujkowski, L Hong, RJ Wessells, SV Todi Ageing Research Reviews 74, 101543, 2022	98	2022
JosD1, a membrane-targeted deubiquitinating enzyme, is activated by ubiquitination and regulates membrane dynamics, cell motility, and endocytosis T Seki, L Gong, AJ Williams, N Sakai, SV Todi, HL Paulson Journal of Biological Chemistry 288 (24), 17145-17155, 2013	85	2013
Understanding the role of the Josephin domain in the PolyUb binding and cleavage properties of ataxin-3 G Nicastro, SV Todi, E Karaca, AMJJ Bonvin, HL Paulson, A Pastore PloS one 5 (8), e12430, 2010	85	2010
Ubiquitin-specific protease 25 functions in Endoplasmic Reticulum-associated degradation JR Blount, AA Burr, A Denuc, G Marfany, SV Todi PloS one 7 (5), e36542, 2012	82	2012
Systematic analysis of the physiological importance of deubiquitinating enzymes WL Tsou, MJ Sheedlo, ME Morrow, JR Blount, KM McGregor, C Das, ... Public Library of Science 7 (8), e43112, 2012	80	2012
Ubiquitin-binding site 2 of ataxin-3 prevents its proteasomal degradation by interacting with Rad23 JR Blount, WL Tsou, G Ristic, AA Burr, M Ouyang, H Galante, ... Nature communications 5 (1), 4638, 2014	74	2014
Cellular turnover of the polyglutamine disease protein ataxin-3 is regulated by its catalytic activity SV Todi, MN Laco, BJ Winborn, SM Travis, HM Wen, HL Paulson Journal of Biological Chemistry 282 (40), 29348-29358, 2007	73	2007
Ubiquitination regulates the neuroprotective function of the deubiquitinase ataxin-3 in vivo WL Tsou, AA Burr, M Ouyang, JR Blount, KM Scaglione, SV Todi Journal of Biological Chemistry 288 (48), 34460-34469, 2013	67	2013
Inhibition of alpha-synuclein aggregation by multifunctional dopamine agonists assessed by a novel in vitro assay and an in vivo Drosophila synucleinopathy model D Yedlapudi, GS Joshi, D Luo, SV Todi, AK Dutta Scientific reports 6 (1), 38510, 2016	63	2016

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