Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells G Germano, R Frapolli, M Simone, M Tavecchio, E Erba, S Pesce, ... Cancer research 70 (6), 2235-2244, 2010 | 305 | 2010 |
Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors C Forni, M Minuzzo, E Virdis, E Tamborini, M Simone, M Tavecchio, ... Molecular cancer therapeutics 8 (2), 449-457, 2009 | 201 | 2009 |
DNA-PK inhibition by NU7441 sensitizes breast cancer cells to ionizing radiation and doxorubicin WM Ciszewski, M Tavecchio, J Dastych, NJ Curtin Breast cancer research and treatment 143, 47-55, 2014 | 178 | 2014 |
The isothiocyanate produced from glucomoringin inhibits NF-kB and reduces myeloma growth in nude mice in vivo D Brunelli, M Tavecchio, C Falcioni, R Frapolli, E Erba, R Iori, P Rollin, ... Biochemical pharmacology 79 (8), 1141-1148, 2010 | 166 | 2010 |
Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K JM Munck, MA Batey, Y Zhao, H Jenkins, CJ Richardson, C Cano, ... Molecular cancer therapeutics 11 (8), 1789-1798, 2012 | 150 | 2012 |
Role of homologous recombination in trabectedin-induced DNA damage M Tavecchio, M Simone, E Erba, I Chiolo, G Liberi, M Foiani, M D’Incalci, ... European Journal of Cancer 44 (4), 609-618, 2008 | 131 | 2008 |
Adaptive mitochondrial reprogramming and resistance to PI3K therapy JC Ghosh, MD Siegelin, V Vaira, A Faversani, M Tavecchio, YC Chae, ... Journal of the National Cancer Institute 107 (3), dju502, 2015 | 115 | 2015 |
Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1α S Basu, K Gnanapradeepan, T Barnoud, CP Kung, M Tavecchio, J Scott, ... Genes & development 32 (3-4), 230-243, 2018 | 105 | 2018 |
Further characterisation of the cellular activity of the DNA-PK inhibitor, NU7441, reveals potential cross-talk with homologous recombination M Tavecchio, JM Munck, C Cano, DR Newell, NJ Curtin Cancer chemotherapy and pharmacology 69, 155-164, 2012 | 84 | 2012 |
Deletion of the mitochondrial chaperone TRAP-1 uncovers global reprogramming of metabolic networks S Lisanti, M Tavecchio, YC Chae, Q Liu, AK Brice, ML Thakur, ... Cell Reports 8 (3), 671-677, 2014 | 71 | 2014 |
Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease BH Kang, M Tavecchio, HL Goel, CC Hsieh, DS Garlick, CM Raskett, ... British journal of cancer 104 (4), 629-634, 2011 | 71 | 2011 |
Cyclophilin D Extramitochondrial Signaling Controls Cell Cycle Progression and Chemokine-directed Cell Motility*[S] M Tavecchio, S Lisanti, A Lam, JC Ghosh, NM Martin, M O'Connell, ... Journal of Biological Chemistry 288 (8), 5553-5561, 2013 | 56 | 2013 |
Deletion of cyclophilin D impairs β-oxidation and promotes glucose metabolism M Tavecchio, S Lisanti, MJ Bennett, LR Languino, DC Altieri Scientific reports 5 (1), 15981, 2015 | 51 | 2015 |
Checkpoint kinase 1 down-regulation by an inducible small interfering RNA expression system sensitized in vivo tumors to treatment with 5-fluorouracil M Ganzinelli, L Carrassa, F Crippa, M Tavecchio, M Broggini, G Damia Clinical Cancer Research 14 (16), 5131-5141, 2008 | 50 | 2008 |
Atypical retinoids ST1926 and CD437 are S-phase-specific agents causing DNA double-strand breaks: significance for the cytotoxic and antiproliferative activity C Valli, G Paroni, AM Di Francesco, R Riccardi, M Tavecchio, E Erba, ... Molecular cancer therapeutics 7 (9), 2941-2954, 2008 | 49 | 2008 |
Antitumor activity of the retinoid-related molecules (E)-3-(4′-hydroxy-3′-adamantylbiphenyl-4-yl) acrylic acid (ST1926) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene … E Parrella, M Giannì, M Fratelli, MM Barzago, I Raska, L Diomede, ... Molecular pharmacology 70 (3), 909-924, 2006 | 48 | 2006 |
Transgenic expression of the mitochondrial chaperone TNFR-associated protein 1 (TRAP1) accelerates prostate cancer development S Lisanti, DS Garlick, KG Bryant, M Tavecchio, GB Mills, Y Lu, ... Journal of Biological Chemistry 291 (48), 25247-25254, 2016 | 38 | 2016 |
Dynamics of cell cycle phase perturbations by trabectedin (ET‐743) in nucleotide excision repair (NER)‐deficient and NER‐proficient cells, unravelled by a novel mathematical … M Tavecchio, C Natoli, P Ubezio, E Erba, M D’Incalci Cell proliferation 40 (6), 885-904, 2007 | 24 | 2007 |
Chk2 phosphorylation of survivin-ΔEx3 contributes to a DNA damage–sensing checkpoint in cancer A Lopergolo, M Tavecchio, S Lisanti, JC Ghosh, T Dohi, A Faversani, ... Cancer research 72 (13), 3251-3259, 2012 | 22 | 2012 |
Multi-parametric flow cytometric cell cycle analysis using TO-PRO-3 iodide (TP3): detailed protocols M Tavecchio, M Simone, S Bernasconi, G Tognon, G Mazzini, E Erba Acta histochemica 110 (3), 232-244, 2008 | 20 | 2008 |