Oscillatory flow reactors (OFRs) for continuous manufacturing and crystallization T McGlone, NEB Briggs, CA Clark, CJ Brown, J Sefcik, AJ Florence Organic Process Research & Development 19 (9), 1186-1202, 2015 | 248 | 2015 |
A strategy for producing predicted polymorphs: catemeric carbamazepine form V JB Arlin, LS Price, SL Price, AJ Florence Chemical Communications 47 (25), 7074-7076, 2011 | 244 | 2011 |
Achieving continuous manufacturing: technologies and approaches for synthesis, workup, and isolation of drug substance. May 20–21, 2014 Continuous Manufacturing Symposium IR Baxendale, RD Braatz, BK Hodnett, KF Jensen, MD Johnson, ... Journal of pharmaceutical sciences 104 (3), 781-791, 2015 | 225 | 2015 |
Continuous manufacturing in pharmaceutical process development and manufacturing CL Burcham, AJ Florence, MD Johnson Annual review of chemical and biomolecular engineering 9 (1), 253-281, 2018 | 177 | 2018 |
A single-crystal neutron diffraction study of the temperature dependence of hydrogen-atom disorder in benzoic acid dimers CC Wilson, N Shankland, AJ Florence Journal of the Chemical Society, Faraday Transactions 92 (24), 5051-5057, 1996 | 164 | 1996 |
An automated parallel crystallisation search for predicted crystal structures and packing motifs of carbamazepine AJ Florence, A Johnston, SL Price, H Nowell, AR Kennedy, N Shankland Journal of pharmaceutical sciences 95 (9), 1918-1930, 2006 | 154 | 2006 |
Exploring the experimental and computed crystal energy landscape of olanzapine RM Bhardwaj, LS Price, SL Price, SM Reutzel-Edens, GJ Miller, ... Crystal Growth & Design 13 (4), 1602-1617, 2013 | 141 | 2013 |
Why we need continuous pharmaceutical manufacturing and how to make it happen C Badman, CL Cooney, A Florence, K Konstantinov, M Krumme, S Mascia, ... Journal of pharmaceutical sciences 108 (11), 3521-3523, 2019 | 140 | 2019 |
Refinement of ibuprofen at 100K by single-crystal pulsed neutron diffraction N Shankland, CC Wilson, AJ Florence, PJ Cox Crystal Structure Communications 53 (7), 951-954, 1997 | 137 | 1997 |
Reversible extrusion and uptake of HCl molecules by crystalline solids involving coordination bond cleavage and formation G Mínguez Espallargas, L Brammer, J van de Streek, K Shankland, ... Journal of the American Chemical Society 128 (30), 9584-9585, 2006 | 126 | 2006 |
Regulatory perspectives on continuous pharmaceutical manufacturing: moving from theory to practice: September 26-27, 2016, international symposium on the continuous … MM Nasr, M Krumme, Y Matsuda, BL Trout, C Badman, S Mascia, ... Journal of pharmaceutical sciences 106 (11), 3199-3206, 2017 | 121 | 2017 |
Solving molecular crystal structures from laboratory X-ray powder diffraction data with DASH: the state of the art and challenges AJ Florence, N Shankland, K Shankland, WIF David, E Pidcock, X Xu, ... Applied Crystallography 38 (2), 249-259, 2005 | 120 | 2005 |
Complex Polymorphic System of Gallic Acid Five Monohydrates, Three Anhydrates, and over 20 Solvates DE Braun, RM Bhardwaj, AJ Florence, DA Tocher, SL Price Crystal growth & design 13 (1), 19-23, 2013 | 113 | 2013 |
Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations CJ Brown, T McGlone, S Yerdelen, V Srirambhatla, F Mabbott, R Gurung, ... Molecular Systems Design & Engineering 3 (3), 518-549, 2018 | 110 | 2018 |
Development of a hot-melt extrusion (HME) process to produce drug loaded Affinisol™ 15LV filaments for fused filament fabrication (FFF) 3D printing E Prasad, MT Islam, DJ Goodwin, AJ Megarry, GW Halbert, AJ Florence, ... Additive Manufacturing 29, 100776, 2019 | 109 | 2019 |
Seeded Crystallization of β-l-Glutamic Acid in a Continuous Oscillatory Baffled Crystallizer NEB Briggs, U Schacht, V Raval, T McGlone, J Sefcik, AJ Florence Organic Process Research & Development 19 (12), 1903-1911, 2015 | 109 | 2015 |
Characterisation of amorphous and nanocrystalline molecular materials by total scattering SJL Billinge, T Dykhne, P Juhás, E Božin, R Taylor, AJ Florence, ... CrystEngComm 12 (5), 1366-1368, 2010 | 106 | 2010 |
From discovery to scale-up: α-lipoic acid: nicotinamide co-crystals in a continuous oscillatory baffled crystalliser L Zhao, V Raval, NEB Briggs, RM Bhardwaj, T McGlone, IDH Oswald, ... CrystEngComm 16 (26), 5769-5780, 2014 | 104 | 2014 |
Direct determination of the temperature dependence of proton transfer in the benzoic acid dimer by single crystal neutron diffraction CC Wilson, N Shankland, AJ Florence Chemical physics letters 253 (1-2), 103-107, 1996 | 103 | 1996 |
Data requirements for the reliable use of atomic pair distribution functions in amorphous pharmaceutical fingerprinting T Dykhne, R Taylor, A Florence, SJL Billinge Pharmaceutical research 28, 1041-1048, 2011 | 96 | 2011 |