| Buparlisib in patients with recurrent glioblastoma harboring phosphatidylinositol 3-kinase pathway activation: an open-label, multicenter, multi-arm, phase II trial PY Wen, M Touat, BM Alexander, IK Mellinghoff, S Ramkissoon, ... Journal of clinical oncology 37 (9), 741-750, 2019 | 159 | 2019 |
| PARP-mediated PARylation of MGMT is critical to promote repair of temozolomide-induced O6-methylguanine DNA damage in glioblastoma S Wu, X Li, F Gao, JF De Groot, D Koul, WKA Yung Neuro-oncology 23 (6), 920-931, 2021 | 96 | 2021 |
| Hypoxia-inducible factor-1α-induced differentiation of myeloid leukemic cells is its transcriptional activity independent LP Song, J Zhang, SF Wu, Y Huang, Q Zhao, JP Cao, YL Wu, LS Wang, ... Oncogene 27 (4), 519-527, 2008 | 88 | 2008 |
| Casein Kinase 1α Regulates an MDMX Intramolecular Interaction To Stimulate p53 Binding S Wu, L Chen, A Becker, E Schonbrunn, J Chen Molecular and cellular biology 32 (23), 4821-4832, 2012 | 60 | 2012 |
| CCAAT/enhancer-binding protein α antagonizes transcriptional activity of hypoxia-inducible factor 1 α with direct protein–protein interaction L Yang, Y Jiang, SF Wu, MY Zhou, YL Wu, GQ Chen Carcinogenesis 29 (2), 291-298, 2008 | 56 | 2008 |
| Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation N Noureen, S Wu, Y Lv, J Yang, WK Alfred Yung, J Gelfond, X Wang, ... Nature communications 12 (1), 139, 2021 | 55 | 2021 |
| Autoinhibition of MDMX by intramolecular p53 mimicry L Chen, W Borcherds, S Wu, A Becker, E Schonbrunn, GW Daughdrill, ... Proceedings of the National Academy of Sciences 112 (15), 4624-4629, 2015 | 55 | 2015 |
| Secondary interaction between MDMX and p53 core domain inhibits p53 DNA binding X Wei, S Wu, T Song, L Chen, M Gao, W Borcherds, GW Daughdrill, ... Proceedings of the National Academy of Sciences 113 (19), E2558-E2563, 2016 | 52 | 2016 |
| The downregulation of onzin expression by PKCepsilon-ERK2 signaling and its potential role in AML cell differentiation SF Wu, Y Huang, JK Hou, TT Yuan, CX Zhou, J Zhang, GQ Chen Leukemia 24 (3), 544-551, 2010 | 45 | 2010 |
| Activation of WEE1 confers resistance to PI3K inhibition in glioblastoma S Wu, S Wang, F Gao, L Li, S Zheng, WKA Yung, D Koul Neuro-oncology 20 (1), 78-91, 2018 | 41 | 2018 |
| EGFR Amplification Induces Increased DNA Damage Response and Renders Selective Sensitivity to Talazoparib (PARP Inhibitor) in Glioblastoma S Wu, F Gao, S Zheng, C Zhang, E Martinez-Ledesma, R Ezhilarasan, ... Clinical Cancer Research 26 (6), 1395-1407, 2020 | 40 | 2020 |
| MSK1-mediated β-catenin phosphorylation confers resistance to PI3K/mTOR inhibitors in glioblastoma S Wu, S Wang, S Zheng, R Verhaak, D Koul, WKA Yung Molecular cancer therapeutics 15 (7), 1656-1668, 2016 | 31 | 2016 |
| Preventive and therapeutic effects of adenanthin on experimental autoimmune encephalomyelitis by inhibiting NF-κB signaling QQ Yin, CX Liu, YL Wu, SF Wu, Y Wang, X Zhang, XJ Hu, JX Pu, Y Lu, ... The Journal of Immunology 191 (5), 2115-2125, 2013 | 26 | 2013 |
| Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma D Koul, S Wang, S Wu, N Saito, S Zheng, F Gao, I Kaul, M Setoguchi, ... Oncotarget 8 (13), 21741, 2017 | 24 | 2017 |
| TIE2–FGFR1 interaction induces adaptive PI3K inhibitor resistance by upregulating Aurora A/PlK1/CDK1 signaling in glioblastoma X Li, E Martinez-Ledesma, C Zhang, F Gao, S Zheng, J Ding, S Wu, ... Cancer Research 79 (19), 5088-5101, 2019 | 23 | 2019 |
| APOBEC3G acts as a therapeutic target in mesenchymal gliomas by sensitizing cells to radiation-induced cell death Y Wang, S Wu, S Zheng, S Wang, A Wali, R Ezhilarasan, EP Sulman, ... Oncotarget 8 (33), 54285, 2017 | 21 | 2017 |
| The polo-like kinase 1 inhibitor volasertib synergistically increases radiation efficacy in glioma stem cells J Dong, SY Park, N Nguyen, R Ezhilarasan, E Martinez-Ledesma, S Wu, ... Oncotarget 9 (12), 10497, 2018 | 20 | 2018 |
| BRCA1 identified as a modulator of temozolomide resistance in P53 wild-type GBM using a high-throughput shRNA-based synthetic lethality screening J Ding, S Wu, C Zhang, A Garyali, E Martinez-Ledesma, F Gao, ... American Journal of Cancer Research 9 (11), 2428, 2019 | 13 | 2019 |
| PU. 1 directly regulates retinoic acid-induced expression of RIG-G in leukemia cells ZM Gu, CX Liu, SF Wu, M Zhao, HZ Xu, W Liu, HC Zhou, GQ Chen, YL Wu FEBS letters 585 (2), 375-380, 2011 | 10 | 2011 |
| Effect of block deletions in the C-terminus on the functional expression of human anion exchanger 1 (AE1) Y Wang, SF Wu, GQ Chen, GH Fu Molecular Membrane Biology 24 (1), 65-73, 2007 | 9 | 2007 |
