| Branched-chain amino acids in metabolic signalling and insulin resistance CJ Lynch, SH Adams Nature Reviews Endocrinology 10 (12), 723-736, 2014 | 1406 | 2014 |
| Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism P She, C Van Horn, T Reid, SM Hutson, RN Cooney, CJ Lynch American Journal of Physiology-Endocrinology and Metabolism 293 (6), E1552-E1563, 2007 | 555 | 2007 |
| Catabolic defect of branched-chain amino acids promotes heart failure H Sun, KC Olson, C Gao, DA Prosdocimo, M Zhou, Z Wang, D Jeyaraj, ... Circulation 133 (21), 2038-2049, 2016 | 499 | 2016 |
| Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels MA Herman, P She, OD Peroni, CJ Lynch, BB Kahn Journal of Biological Chemistry 285 (15), 11348-11356, 2010 | 427 | 2010 |
| Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle P She, TM Reid, SK Bronson, TC Vary, A Hajnal, CJ Lynch, SM Hutson Cell metabolism 6 (3), 181-194, 2007 | 415 | 2007 |
| Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity DE Lackey, CJ Lynch, KC Olson, R Mostaedi, M Ali, WH Smith, F Karpe, ... American Journal of Physiology-Endocrinology and Metabolism 304 (11), E1175 …, 2013 | 345 | 2013 |
| Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity J Li, C Romestaing, X Han, Y Li, X Hao, Y Wu, C Sun, X Liu, LS Jefferson, ... Cell metabolism 12 (2), 154-165, 2010 | 319 | 2010 |
| Inhibition of hepatic alpha 1-adrenergic effects and binding by phorbol myristate acetate. CJ Lynch, R Charest, SB Bocckino, JH Exton, PF Blackmore Journal of Biological Chemistry 260 (5), 2844-2851, 1985 | 265 | 1985 |
| Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells G Lu, H Sun, P She, JY Youn, S Warburton, P Ping, TM Vondriska, H Cai, ... The Journal of clinical investigation 119 (6), 1678-1687, 2009 | 242 | 2009 |
| Leucine is a direct-acting nutrient signal that regulates protein synthesis in adipose tissue CJ Lynch, BJ Patson, J Anthony, A Vaval, LS Jefferson, TC Vary American Journal of Physiology-Endocrinology and Metabolism 283 (3), E503-E513, 2002 | 225 | 2002 |
| Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents VL Albaugh, CR Henry, NT Bello, A Hajnal, SL Lynch, B Halle, CJ Lynch Obesity 14 (1), 36-51, 2006 | 220 | 2006 |
| Role of leucine in the regulation of mTOR by amino acids: revelations from structure–activity studies CJ Lynch The Journal of nutrition 131 (3), 861S-865S, 2001 | 211 | 2001 |
| Regulation of amino acid–sensitive TOR signaling by leucine analogues in adipocytes CJ Lynch, HL Fox, TC Vary, LS Jefferson, SR Kimball Journal of cellular biochemistry 77 (2), 234-251, 2000 | 199 | 2000 |
| Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice NM Agostino, VM Chinchilli, CJ Lynch, A Koszyk-Szewczyk, R Gingrich, ... Journal of Oncology Pharmacy Practice 17 (3), 197-202, 2011 | 190 | 2011 |
| Leucine in food mediates some of the postprandial rise in plasma leptin concentrations CJ Lynch, B Gern, C Lloyd, SM Hutson, R Eicher, TC Vary American Journal of Physiology-Endocrinology and Metabolism 291 (3), E621-E630, 2006 | 176 | 2006 |
| Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats CJ Lynch, SM Hutson, BJ Patson, A Vaval, TC Vary American Journal of Physiology-Endocrinology and Metabolism 283 (4), E824-E835, 2002 | 172 | 2002 |
| Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism AC Shin, M Fasshauer, N Filatova, LA Grundell, E Zielinski, JY Zhou, ... Cell metabolism 20 (5), 898-909, 2014 | 166 | 2014 |
| Amino acids stimulate phosphorylation of p70 S6k and organization of rat adipocytes into multicellular clusters HL Fox, SR Kimball, LS Jefferson, CJ Lynch American Journal of Physiology-Cell Physiology 274 (1), C206-C213, 1998 | 164 | 1998 |
| Defining meal requirements for protein to optimize metabolic roles of amino acids DK Layman, TG Anthony, BB Rasmussen, SH Adams, CJ Lynch, ... The American journal of clinical nutrition 101 (6), 1330S-1338S, 2015 | 162 | 2015 |
| Amino acid effects on translational repressor 4E-BP1 are mediated primarily by L-leucine in isolated adipocytes HL Fox, PT Pham, SR Kimball, LS Jefferson, CJ Lynch American Journal of Physiology-Cell Physiology 275 (5), C1232-C1238, 1998 | 157 | 1998 |