Jens Luebeck

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Vineet BafnaProfessor of Computer Science & Engineering, UCSDVerifisert e-postadresse på ucsd.edu
Paul MischelStanford UniversityVerifisert e-postadresse på stanford.edu
Viraj B DeshpandeUniversity of California-San Diego, Illumina Inc.Verifisert e-postadresse på eng.ucsd.edu
Howard Y. ChangStanford UniversityVerifisert e-postadresse på stanford.edu
Nam-phuong Nguyen858 TherapeuticsVerifisert e-postadresse på 8five8tx.com
Prashant MaliProfessor, Bioengineering Department, UCSDVerifisert e-postadresse på ucsd.edu
Utkrisht C RajkumarMachine Learning Scientist at AmazonVerifisert e-postadresse på ucsd.edu
Trey IdekerUniversity of California San DiegoVerifisert e-postadresse på ucsd.edu
Sihan WuChildren’s Medical Center Research Institute, University of Texas Southwestern Medical CenterVerifisert e-postadresse på utsouthwestern.edu
Amanda BirminghamSenior Bioinformatics Programmer; University of California, San DiegoVerifisert e-postadresse på ucsd.edu
Hoon KimSchool of Pharmacy, Sungkyunkwan UniversityVerifisert e-postadresse på skku.edu
Roel VerhaakYale UniversityVerifisert e-postadresse på yale.edu
John Paul ShenAssistant Professor, University of Texas MD Anderson Cancer CenterVerifisert e-postadresse på alum.mit.edu
Anton G. HenssenExperimental and Clinical Research Center (ECRC) of the Max Delbrück Center (MDC) and CharitéVerifisert e-postadresse på charite.de
Ludmil B. AlexandrovProfessor, University of California San DiegoVerifisert e-postadresse på ucsd.edu
Joshua T. LangePh.D. Candidate, University of California, San DiegoVerifisert e-postadresse på ucsd.edu
Richard B. SchwabSenior Medical Director, GenentechVerifisert e-postadresse på gene.com
Hannah CarterAssociate Professor, University of California San DiegoVerifisert e-postadresse på ucsd.edu
Aaron N. ChangPrime MedicineVerifisert e-postadresse på primemedicine.com
Chih-Chung KuoVerifisert e-postadresse på ucsd.edu

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Jens Luebeck

University of California San Diego

Verifisert e-postadresse på ucsd.edu - Startside

ecDNA bioinformatics computational biology gene amplification cancer genomics


Tittel Sorter etter sitater Sorter etter år Sorter etter tittel	Sitert av Sitert av	År
Circular ecDNA promotes accessible chromatin and high oncogene expression S Wu, KM Turner, N Nguyen, R Raviram, M Erb, J Santini, J Luebeck, ... Nature 575 (7784), 699-703, 2019	459	2019
Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions JP Shen, D Zhao, R Sasik, J Luebeck, A Birmingham, ... Nature methods 14 (6), 573-576, 2017	389	2017
Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers H Kim, NP Nguyen, K Turner, S Wu, AD Gujar, J Luebeck, J Liu, ... Nature Genetics 52 (9), 891-897, 2020	375	2020
Exploring the landscape of focal amplifications in cancer using AmpliconArchitect V Deshpande, J Luebeck, NPD Nguyen, M Bakhtiari, KM Turner, ... Nature communications 10 (1), 392, 2019	251	2019
Quantitative missense variant effect prediction using large-scale mutagenesis data VE Gray, RJ Hause, J Luebeck, J Shendure, DM Fowler Cell systems 6 (1), 116-124. e3, 2018	207	2018
EcDNA hubs drive cooperative intermolecular oncogene expression KL Hung, KE Yost, L Xie, Q Shi, K Helmsauer, J Luebeck, R Schöpflin, ... Nature 600 (7890), 731-736, 2021	197	2021
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA EN Bergstrom, J Luebeck, M Petljak, A Khandekar, M Barnes, T Zhang, ... Nature 602 (7897), 510-517, 2022	110	2022
Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis D Zhao, MG Badur, J Luebeck, JH Magaña, A Birmingham, R Sasik, ... Molecular cell 69 (4), 699-708. e7, 2018	99	2018
AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications J Luebeck, C Coruh, SR Dehkordi, JT Lange, KM Turner, V Deshpande, ... Nature Communications 11 (1), 1-14, 2020	77	2020
Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH KL Hung, J Luebeck, SR Dehkordi, CI Colón, R Li, ITL Wong, C Coruh, ... Nature Genetics, 1-9, 2022	74	2022
Extrachromosomal DNA in the cancerous transformation of Barrett’s oesophagus J Luebeck, AWT Ng, PC Galipeau, X Li, CA Sanchez, ... Nature, 1-8, 2023	72	2023
Epigenetic dysregulation from chromosomal transit in micronuclei AS Agustinus, D Al-Rawi, B Dameracharla, R Raviram, BSCL Jones, ... Nature 619 (7968), 176-183, 2023	61	2023
ViFi: accurate detection of viral integration and mRNA fusion reveals indiscriminate and unregulated transcription in proximal genomic regions in cervical cancer ND Nguyen, V Deshpande, J Luebeck, PS Mischel, V Bafna Nucleic acids research 46 (7), 3309-3325, 2018	59	2018
Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges K Song, JK Minami, A Huang, SR Dehkordi, SH Lomeli, J Luebeck, ... Cancer discovery 12 (4), 1046-1069, 2022	47	2022
EcSeg: Semantic Segmentation of Metaphase Images Containing Extrachromosomal DNA U Rajkumar, K Turner, J Luebeck, V Deshpande, M Chandraker, ... iScience 21, 428-435, 2019	41	2019
CRISPR-Cas9 gene editing of hematopoietic stem cells from patients with Friedreich’s ataxia CJ Rocca, JN Rainaldi, J Sharma, Y Shi, JH Haquang, J Luebeck, P Mali, ... Molecular Therapy-Methods & Clinical Development 17, 1026-1036, 2020	31	2020
Extrachromosomal DNA in HPV-Mediated Oropharyngeal Cancer Drives Diverse Oncogene Transcription J Pang, N Nguyen, J Luebeck, L Ball, A Finegersh, S Ren, T Nakagawa, ... Clinical Cancer Research 27 (24), 6772-6786, 2021	30	2021
Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma OS Chapman, J Luebeck, S Sridhar, ITL Wong, D Dixit, S Wang, G Prasad, ... Nature Genetics, 1-11, 2023	24*	2023
FaNDOM: Fast nested distance-based seeding of optical maps SR Dehkordi, J Luebeck, V Bafna Patterns 2 (5), 2021	16	2021
Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity R Raviram, A Raman, S Preissl, J Ning, S Wu, T Koga, K Zhang, ... Proceedings of the National Academy of Sciences 120 (20), e2210991120, 2023	10	2023

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