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Farhia Kabeer
Farhia Kabeer
Post-doctoral Research Fellow at University of British Columbia
Verifisert e-postadresse på bccrc.ca - Startside
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CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours
H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ND Santos, ...
Nature communications 8 (1), 14432, 2017
5512017
Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses
CH O’Flanagan, KR Campbell, AW Zhang, F Kabeer, JLP Lim, J Biele, ...
Genome biology 20, 1-13, 2019
2502019
Clonal decomposition and DNA replication states defined by scaled single-cell genome sequencing
E Laks, A McPherson, H Zahn, D Lai, A Steif, J Brimhall, J Biele, B Wang, ...
Cell 179 (5), 1207-1221. e22, 2019
2372019
Clonal fitness inferred from time-series modelling of single-cell cancer genomes
S Salehi, F Kabeer, N Ceglia, M Andronescu, MJ Williams, KR Campbell, ...
Nature 595 (7868), 585-590, 2021
1192021
clonealign: statistical integration of independent single-cell RNA and DNA sequencing data from human cancers
KR Campbell, A Steif, E Laks, H Zahn, D Lai, A McPherson, H Farahani, ...
Genome biology 20, 1-12, 2019
1082019
Single-cell genomic variation induced by mutational processes in cancer
T Funnell, CH O’Flanagan, MJ Williams, A McPherson, S McKinney, ...
Nature 612 (7938), 106-115, 2022
952022
Cancer phylogenetic tree inference at scale from 1000s of single cell genomes
S Salehi, F Dorri, K Chern, F Kabeer, N Rusk, T Funnell, MJ Williams, ...
Peer Community Journal 3, 2023
282023
Epiclomal: probabilistic clustering of sparse single-cell DNA methylation data
C PE de Souza, M Andronescu, T Masud, F Kabeer, J Biele, E Laks, D Lai, ...
PLOS Computational Biology 16 (9), e1008270, 2020
272020
Resource: Scalable whole genome sequencing of 40,000 single cells identifies stochastic aneuploidies, genome replication states and clonal repertoires
E Laks, H Zahn, D Lai, A McPherson, A Steif, J Brimhall, J Biele, B Wang, ...
BioRxiv, 411058, 2018
222018
Methods to study metastasis in genetically modified mice
F Kabeer, LJ Beverly, G Darrasse-Jèze, K Podsypanina
Cold Spring Harbor Protocols 2016 (2), pdb. top069948, 2016
152016
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. Nat Commun. 2017; 8: 14432
H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ND Santos, ...
9
Single cell fitness landscapes induced by genetic and pharmacologic perturbations in cancer
S Salehi, F Kabeer, N Ceglia, M Andronescu, M Williams, KR Campbell, ...
bioRxiv, 2020.05. 08.081349, 2020
82020
The impact of mutational processes on structural genomic plasticity in cancer cells
T Funnell, CH O’Flanagan, MJ Williams, A McPherson, S McKinney, ...
Biorxiv, 2021.06. 03.446999, 2021
72021
Evolutionary tracking of cancer haplotypes at single-cell resolution
MJ Williams, T Funnell, CH O’Flanagan, A McPherson, S Salehi, ...
Biorxiv, 2021.06. 04.447031, 2021
62021
GeneVector: Identification of transcriptional programs using dense vector representations defined by mutual information
N Ceglia, Z Sethna, F Uhlitz, V Bojilova, N Rusk, B Burman, A Chow, ...
bioRxiv, 2022.04. 22.487554, 2022
52022
et alCRUK IMAXT Grand Challenge Team. Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress …
CH O’Flanagan, KR Campbell, AW Zhang
Genome Biol 20, 210, 2019
42019
Identification of transcriptional programs using dense vector representations defined by mutual information with GeneVector
N Ceglia, Z Sethna, SS Freeman, F Uhlitz, V Bojilova, N Rusk, B Burman, ...
Nature Communications 14 (1), 4400, 2023
32023
Tissue dissociation for metastasis studies
F Kabeer, K Podsypanina
Cold Spring Harbor Protocols 2016 (2), pdb. prot078329, 2016
22016
Single-cell decoding of drug induced transcriptomic reprogramming in triple negative breast cancers
F Kabeer, H Tran, M Andronescu, G Singh, H Lee, S Salehi, B Wang, ...
Genome Biology 25 (1), 191, 2024
12024
clonealign: statistical integration of independent single-cell RNA & DNA-seq from human cancers
KR Campbell, A Steif, E Laks, H Zahn, D Lai, A McPherson, H Farahani, ...
bioRxiv, 344309, 2018
12018
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