| Differential requirements for eIF4E dose in normal development and cancer ML Truitt, CS Conn, Z Shi, X Pang, T Tokuyasu, AM Coady, Y Seo, ... Cell 162 (1), 59-71, 2015 | 383 | 2015 |
| ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression F Tameire, II Verginadis, NM Leli, C Polte, CS Conn, R Ojha, ... Nature cell biology 21 (7), 889-899, 2019 | 237 | 2019 |
| Oncogenic KRAS regulates amino acid homeostasis and asparagine biosynthesis via ATF4 and alters sensitivity to L-asparaginase DM Gwinn, AG Lee, M Briones-Martin-del-Campo, CS Conn, DR Simpson, ... Cancer cell 33 (1), 91-107. e6, 2018 | 230 | 2018 |
| Development of a stress response therapy targeting aggressive prostate cancer HG Nguyen, CS Conn, Y Kye, L Xue, CM Forester, JE Cowan, AC Hsieh, ... Science translational medicine 10 (439), eaar2036, 2018 | 162 | 2018 |
| Ribosomal proteins regulate MHC class I peptide generation for immunosurveillance J Wei, RJ Kishton, M Angel, CS Conn, N Dalla-Venezia, V Marcel, ... Molecular cell 73 (6), 1162-1173. e5, 2019 | 112 | 2019 |
| Nutrient signaling in protein homeostasis: an increase in quantity at the expense of quality CS Conn, SB Qian Science signaling 6 (271), ra24-ra24, 2013 | 84 | 2013 |
| mTOR signaling in protein homeostasis: less is more? CS Conn, SB Qian Cell cycle 10 (12), 1940-1947, 2011 | 78 | 2011 |
| Translational control of the cytosolic stress response by mitochondrial ribosomal protein L18 X Zhang, X Gao, RA Coots, CS Conn, B Liu, SB Qian Nature structural & molecular biology 22 (5), 404-410, 2015 | 77 | 2015 |
| PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy D Zhang, AM Li, G Hu, M Huang, F Yang, L Zhang, KE Wellen, X Xu, ... Cell metabolism 35 (3), 517-534. e8, 2023 | 59 | 2023 |
| PI3K-mTORC1 attenuates stress response by inhibiting cap-independent Hsp70 translation J Sun, CS Conn, Y Han, V Yeung, SB Qian Journal of Biological Chemistry 286 (8), 6791-6800, 2011 | 56 | 2011 |
| The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity CS Conn, H Yang, HJ Tom, K Ikeda, JA Oses-Prieto, H Vu, Y Oguri, S Nair, ... Nature metabolism 3 (2), 244-257, 2021 | 48 | 2021 |
| Noninvasive Measurement of mTORC1 Signaling with 89Zr-Transferrin C Truillet, JT Cunningham, MFL Parker, LT Huynh, CS Conn, D Ruggero, ... Clinical Cancer Research 23 (12), 3045-3052, 2017 | 29 | 2017 |
| The integrated stress response in cancer progression: a force for plasticity and resistance CL Lines, MJ McGrath, T Dorwart, CS Conn Frontiers in Oncology 13, 1206561, 2023 | 25 | 2023 |
| Reduced eIF4E function impairs B-cell leukemia without altering normal B-lymphocyte function H Chiu, R Buono, LV Jackson, L Herzog, S Mallya, CS Conn, D Ruggero, ... Iscience 24 (7), 2021 | 8 | 2021 |
| Viewing folding of nascent polypeptide chains from ribosomes B Liu, CS Conn, SB Qian Expert review of proteomics 9 (6), 579-581, 2012 | 3 | 2012 |
| ROR2 drives right ventricular heart failure via disruption of proteostasis H Hartman, G Uy, K Uchida, EA Scarborough, Y Yang, E Barr, S Williams, ... bioRxiv, 2025.02. 01.635961, 2025 | | 2025 |
| Biosynthetic plasticity enables CD8+ T cell functional resilience under nutrient stress M Scaglione, M Knight, K Trihemasava, K Rome, AS Archambault, J Oh, ... bioRxiv, 2025.01. 22.632829, 2025 | | 2025 |
| Targeting stress induction of GRP78 by cardiac glycoside oleandrin dually suppresses cancer and COVID-19 DP Ha, WJ Shin, Z Liu, ME Doche, R Lau, NM Leli, CS Conn, M Russo, ... Cell & Bioscience 14 (1), 115, 2024 | | 2024 |
| Abstract Tu051: ROR2 Drives Right Ventricular Failure Via Proteostatic Imbalances J Edwards, G Uy, H Hartman, K Uchida, E Scarborough, Y Yang, E Barr, ... Circulation Research 135 (Suppl_1), ATu051-ATu051, 2024 | | 2024 |
| Cancer Treatment Targeted to Tumor Adaptive Responses to Protein Synthesis Stress D Ruggero, H Nguyen, P Carroll, C Conn US Patent App. 17/576,623, 2022 | | 2022 |
Davide RuggeroProfessor, University of California San Francisco (UCSF)Verifisert e-postadresse på ucsf.edu