Structure of the adenosine A2A receptor in complex with ZM241385 and the xanthines XAC and caffeine AS Doré, N Robertson, JC Errey, I Ng, K Hollenstein, B Tehan, E Hurrell, ... Structure 19 (9), 1283-1293, 2011 | 649 | 2011 |
Extra-helical binding site of a glucagon receptor antagonist A Jazayeri, AS Doré, D Lamb, H Krishnamurthy, SM Southall, AH Baig, ... Nature 533 (7602), 274-277, 2016 | 222 | 2016 |
Structures of human A1 and A2A adenosine receptors with xanthines reveal determinants of selectivity RKY Cheng, E Segala, N Robertson, F Deflorian, AS Doré, JC Errey, ... Structure 25 (8), 1275-1285. e4, 2017 | 221 | 2017 |
Crystal structure of the GLP-1 receptor bound to a peptide agonist A Jazayeri, M Rappas, AJH Brown, J Kean, JC Errey, NJ Robertson, ... Nature 546 (7657), 254-258, 2017 | 209 | 2017 |
The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery N Robertson, A Jazayeri, J Errey, A Baig, E Hurrell, A Zhukov, ... Neuropharmacology 60 (1), 36-44, 2011 | 190 | 2011 |
Identification of Novel Adenosine A2A Receptor Antagonists by Virtual Screening CJ Langmead, SP Andrews, M Congreve, JC Errey, E Hurrell, ... Journal of medicinal chemistry 55 (5), 1904-1909, 2012 | 154 | 2012 |
Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727 N Robertson, M Rappas, AS Doré, J Brown, G Bottegoni, M Koglin, ... Nature 553 (7686), 111-114, 2018 | 135 | 2018 |
Biophysical Mapping of the Adenosine A2A Receptor A Zhukov, SP Andrews, JC Errey, N Robertson, B Tehan, JS Mason, ... Journal of medicinal chemistry 54 (13), 4312-4323, 2011 | 134 | 2011 |
From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer’s disease AJH Brown, SJ Bradley, FH Marshall, GA Brown, KA Bennett, J Brown, ... Cell 184 (24), 5886-5901. e22, 2021 | 62 | 2021 |
How do short chain nonionic detergents destabilize G-protein-coupled receptors? S Lee, A Mao, S Bhattacharya, N Robertson, R Grisshammer, CG Tate, ... Journal of the American Chemical Society 138 (47), 15425-15433, 2016 | 56 | 2016 |
How do branched detergents stabilize GPCRs in micelles? S Lee, S Ghosh, S Jana, N Robertson, CG Tate, N Vaidehi Biochemistry 59 (23), 2125-2134, 2020 | 47 | 2020 |
Mutant proteins and methods for producing them SA Jazayeri-Dezfuly, GP Lebon, FH Marshall, CG Tate, N Robertson US Patent 8,703,915, 2014 | 31 | 2014 |
Development of a novel mammalian display system for selection of antibodies against membrane proteins N Robertson, N Lopez-Anton, SA Gurjar, H Khalique, Z Khalaf, S Clerkin, ... Journal of Biological Chemistry 295 (52), 18436-18448, 2020 | 17 | 2020 |
Mutant g-protein coupled receptor proteins and methods for producing them NJ Robertson, FH Marshall US Patent App. 13/980,497, 2014 | 9 | 2014 |
The role of ICL1 and H8 in class B1 GPCRs; implications for receptor activation I Winfield, K Barkan, S Routledge, NJ Robertson, M Harris, A Jazayeri, ... Frontiers in Endocrinology 12, 792912, 2022 | 8 | 2022 |
Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases AH Lippert, C Paluch, M Gaglioni, MT Vuong, J McColl, E Jenkins, ... Immunity 57 (2), 256-270. e10, 2024 | 6 | 2024 |
Mutant g-protein coupled receptor proteins and methods for producing them NJ Robertson, FH Marshall US Patent App. 15/197,575, 2017 | 5 | 2017 |
Applications and challenges in designing VHH-based bispecific antibodies: leveraging machine learning solutions M Mullin, J McClory, W Haynes, J Grace, N Robertson, G van Heeke Mabs 16 (1), 2341443, 2024 | 3 | 2024 |
Method of Selecting for Antibodies N Lopez-Anton, N Robertson, T Jones, R Cawood, T Payne, ... US Patent App. 17/435,851, 2022 | 1 | 2022 |
Large scale expression and purification of the rat 5-HT2c receptor X He, N Robertson, A Jazayeri, AG Gasperina, G Schertler, X Li Protein expression and purification 106, 1-9, 2015 | 1 | 2015 |