| Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors Y Xia, HK Choi, K Lee European journal of medicinal chemistry 49, 24-40, 2012 | 378 | 2012 |
| Inhibition of NF-κB activation through targeting IκB kinase by celastrol, a quinone methide triterpenoid JH Lee, TH Koo, H Yoon, HS Jung, HZ Jin, K Lee, YS Hong, JJ Lee Biochemical pharmacology 72 (10), 1311-1321, 2006 | 361 | 2006 |
| Bioactive benzofuran derivatives: Moracins A–Z in medicinal chemistry R Naik, DS Harmalkar, X Xu, K Jang, K Lee European journal of medicinal chemistry 90, 379-393, 2015 | 256 | 2015 |
| 2′-Fluoronucleosides RF Schinazi, DC Liotta, CK Chu, JJ McAtee, J Shi, Y Choi, K Lee, ... US Patent 6,348,587, 2002 | 213 | 2002 |
| Structural Determinants of A3 Adenosine Receptor Activation: Nucleoside Ligands at the Agonist/Antagonist Boundary ZG Gao, SK Kim, T Biadatti, W Chen, K Lee, D Barak, SG Kim, ... Journal of medicinal chemistry 45 (20), 4471-4484, 2002 | 180 | 2002 |
| 2′-fluoronucleosides RF Schinazi, DC Liotta, CK Chu, JJ McAtee, J Shi, Y Choi, K Lee, ... US Patent 6,911,424, 2005 | 160 | 2005 |
| (Aryloxyacetylamino) benzoic acid analogues: a new class of hypoxia-inducible factor-1 inhibitors K Lee, JH Lee, SK Boovanahalli, Y Jin, M Lee, X Jin, JH Kim, YS Hong, ... Journal of medicinal chemistry 50 (7), 1675-1684, 2007 | 158 | 2007 |
| Blockade of nuclear factor-κB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analog from Alpinia conchigera JH Lee, HS Jung, PM Giang, X Jin, S Lee, PT Son, D Lee, YS Hong, ... Journal of Pharmacology and Experimental Therapeutics 316 (1), 271-278, 2006 | 156 | 2006 |
| LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1α via upregulation of VHL in a colon cancer cell line K Lee, JE Kang, SK Park, Y Jin, KS Chung, HM Kim, K Lee, MR Kang, ... Biochemical pharmacology 80 (7), 982-989, 2010 | 150 | 2010 |
| Phosphotyrosyl mimetics in the development of signal transduction inhibitors TR Burke, K Lee Accounts of chemical research 36 (6), 426-433, 2003 | 148 | 2003 |
| Hypoxia-Inducible Factor-1 Inhibitory Benzofurans and Chalcone-Derived Diels−Alder Adducts from Morus Species NT Dat, X Jin, K Lee, YS Hong, YH Kim, JJ Lee Journal of natural products 72 (1), 39-43, 2009 | 129 | 2009 |
| Synthesis and Anti-HIV and Anti-HBV Activities of 2‘-Fluoro-2‘,3‘-unsaturated l-Nucleosides K Lee, Y Choi, E Gullen, S Schlueter-Wirtz, RF Schinazi, YC Cheng, ... Journal of medicinal chemistry 42 (7), 1320-1328, 1999 | 128 | 1999 |
| Hypoxia‐inducible factor‐1 (HIF‐1) inhibitors from the last decade (2007 to 2016): A “structure–activity relationship” perspective D Bhattarai, X Xu, K Lee Medicinal research reviews 38 (4), 1404-1442, 2018 | 114 | 2018 |
| 2′-Fluoronucleosides RF Schinazi, DC Liotta, CK Chu, JJ McAtee, J Shi, Y Choi, K Lee, ... US Patent 7,307,065, 2007 | 114 | 2007 |
| Identification of malate dehydrogenase 2 as a target protein of the HIF‐1 inhibitor LW6 using chemical probes K Lee, HS Ban, R Naik, YS Hong, S Son, BK Kim, Y Xia, KB Song, HS Lee, ... Angewandte Chemie International Edition 52 (39), 10286-10289, 2013 | 107 | 2013 |
| Interruption of progerin–lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype SJ Lee, YS Jung, MH Yoon, S Kang, AY Oh, JH Lee, SY Jun, TG Woo, ... The Journal of clinical investigation 126 (10), 3879-3893, 2016 | 103 | 2016 |
| A novel small-molecule inhibitor targeting the IL-6 receptor β subunit, glycoprotein 130 SS Hong, JH Choi, SY Lee, YH Park, KY Park, JY Lee, J Kim, V Gajulapati, ... The Journal of Immunology 195 (1), 237-245, 2015 | 100 | 2015 |
| 2-fluoronucleosides RF Schinazi, DC Liotta, CK Chu, JJ McAtee, J Shi, Y Choi, K Lee, ... US Patent 8,168,583, 2012 | 99 | 2012 |
| Synthesis of amide and urea derivatives of benzothiazole as Raf-1 inhibitor EY Song, N Kaur, MY Park, Y Jin, K Lee, G Kim, KY Lee, JS Yang, ... European journal of medicinal chemistry 43 (7), 1519-1524, 2008 | 95 | 2008 |
| Structure−Activity Relationships of 2‘-Fluoro-2‘,3‘-unsaturated d-Nucleosides as Anti-HIV-1 Agents K Lee, Y Choi, G Gumina, W Zhou, RF Schinazi, CK Chu Journal of medicinal chemistry 45 (6), 1313-1320, 2002 | 94 | 2002 |
