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George Church
George Church
Harvard Medical School
Verifisert e-postadresse på harvard.edu - Startside
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RNA-guided human genome engineering via Cas9
P Mali, L Yang, KM Esvelt, J Aach, M Guell, JE DiCarlo, JE Norville, ...
Science 339 (6121), 823-826, 2013
118572013
Genomic sequencing.
GM Church, W Gilbert
Proceedings of the National Academy of Sciences 81 (7), 1991-1995, 1984
104851984
Systematic determination of genetic network architecture
S Tavazoie, JD Hughes, MJ Campbell, RJ Cho, GM Church
Nature genetics 22 (3), 281-285, 1999
32831999
Biclustering of expression data.
Y Cheng, GM Church
Ismb 8 (2000), 93-103, 2000
31732000
The ENCODE (ENCyclopedia of DNA elements) project
EA Feingold, PJ Good, MS Guyer, S Kamholz, L Liefer, K Wetterstrand, ...
Science 306 (5696), 636-640, 2004
24372004
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
P Mali, J Aach, PB Stranges, KM Esvelt, M Moosburner, S Kosuri, L Yang, ...
Nature biotechnology 31 (9), 833-838, 2013
23442013
A logic-gated nanorobot for targeted transport of molecular payloads
SM Douglas, I Bachelet, GM Church
Science 335 (6070), 831-834, 2012
23272012
Accurate multiplex polony sequencing of an evolved bacterial genome
J Shendure, GJ Porreca, NB Reppas, X Lin, JP McCutcheon, ...
Science 309 (5741), 1728-1732, 2005
22742005
Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems
JE DiCarlo, JE Norville, P Mali, X Rios, J Aach, GM Church
Nucleic acids research 41 (7), 4336-4343, 2013
20712013
A deep learning approach to antibiotic discovery
JM Stokes, K Yang, K Swanson, W Jin, A Cubillos-Ruiz, NM Donghia, ...
Cell 180 (4), 688-702. e13, 2020
20092020
Programming cells by multiplex genome engineering and accelerated evolution
HH Wang, FJ Isaacs, PA Carr, ZZ Sun, G Xu, CR Forest, GM Church
Nature 460 (7257), 894-898, 2009
18832009
Multiplex and homologous recombination–mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9
JF Li, JE Norville, J Aach, M McCormack, D Zhang, J Bush, GM Church, ...
Nature biotechnology 31 (8), 688-691, 2013
18232013
Cas9 as a versatile tool for engineering biology
P Mali, KM Esvelt, GM Church
Nature methods 10 (10), 957-963, 2013
17752013
Highly efficient Cas9-mediated transcriptional programming
A Chavez, J Scheiman, S Vora, BW Pruitt, M Tuttle, E PR Iyer, S Lin, ...
Nature methods 12 (4), 326-328, 2015
16892015
Analysis of optimality in natural and perturbed metabolic networks
D Segre, D Vitkup, GM Church
Proceedings of the national academy of sciences 99 (23), 15112-15117, 2002
16742002
Assessing computational tools for the discovery of transcription factor binding sites
M Tompa, N Li, TL Bailey, GM Church, B De Moor, E Eskin, AV Favorov, ...
Nature biotechnology 23 (1), 137-144, 2005
16202005
Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays
R Drmanac, AB Sparks, MJ Callow, AL Halpern, NL Burns, BG Kermani, ...
Science 327 (5961), 78-81, 2010
15892010
Next-generation digital information storage in DNA
GM Church, Y Gao, S Kosuri
Science 337 (6102), 1628-1628, 2012
15272012
Rapid prototyping of 3D DNA-origami shapes with caDNAno
SM Douglas, AH Marblestone, S Teerapittayanon, A Vazquez, GM Church, ...
Nucleic acids research 37 (15), 5001-5006, 2009
14042009
Computational identification of cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae
JD Hughes, PW Estep, S Tavazoie, GM Church
Journal of molecular biology 296 (5), 1205-1214, 2000
13542000
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Artikler 1–20