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Alexander Skupin
Alexander Skupin
Luxembourg Centre for Systems Biomedicine, University Luxembourg
Verifisert e-postadresse på uni.lu - Startside
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Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment
A Dirkse, A Golebiewska, T Buder, PV Nazarov, A Muller, S Poovathingal, ...
Nature communications 10 (1), 1787, 2019
5232019
Stemness of the hybrid epithelial/mesenchymal state in breast cancer and its association with poor survival
A Grosse-Wilde, A Fouquier d’Hérouël, E McIntosh, G Ertaylan, A Skupin, ...
PloS one 10 (5), e0126522, 2015
3932015
Cell fate decision as high-dimensional critical state transition
M Mojtahedi, A Skupin, J Zhou, IG Castaño, RYY Leong-Quong, H Chang, ...
PLoS biology 14 (12), e2000640, 2016
3532016
Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures
C Sousa, A Golebiewska, SK Poovathingal, T Kaoma, Y Pires‐Afonso, ...
EMBO reports 19 (11), e46171, 2018
2772018
Pro-inflammatory macrophages sustain pyruvate oxidation through pyruvate dehydrogenase for the synthesis of itaconate and to enable cytokine expression
J Meiser, L Krämer, SC Sapcariu, N Battello, J Ghelfi, AF D'Herouel, ...
Journal of Biological Chemistry 291 (8), 3932-3946, 2016
2682016
The contribution of microglia to neuroinflammation in Parkinson’s disease
K Badanjak, S Fixemer, S Smajić, A Skupin, A Grünewald
International Journal of Molecular Sciences 22 (9), 4676, 2021
2292021
How does intracellular Ca2+ oscillate: by chance or by the clock?
A Skupin, H Kettenmann, U Winkler, M Wartenberg, H Sauer, SC Tovey, ...
Biophysical journal 94 (6), 2404-2411, 2008
2102008
Clustering of InsP3 receptors by InsP3 retunes their regulation by InsP3 and Ca2+
A Skupin, M Falcke, CW Taylor
Nature 458 (7238), 655-659, 2009
171*2009
Reliable encoding of stimulus intensities within random sequences of intracellular Ca2+ spikes
K Thurley, SC Tovey, G Moenke, VL Prince, A Meena, AP Thomas, ...
Science signaling 7 (331), ra59-ra59, 2014
1302014
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology
A Golebiewska, AC Hau, A Oudin, D Stieber, YA Yabo, V Baus, ...
Acta Neuropathologica 140, 919-949, 2020
1212020
Calcium signals driven by single channel noise
A Skupin, H Kettenmann, M Falcke
PLoS computational biology 6 (8), e1000870, 2010
1182010
Critical transitions in chronic disease: transferring concepts from ecology to systems medicine
C Trefois, PMA Antony, J Goncalves, A Skupin, R Balling
Current opinion in biotechnology 34, 48-55, 2015
1152015
SARS-CoV-2 transmission risk from asymptomatic carriers: results from a mass screening programme in Luxembourg
P Wilmes, J Zimmer, J Schulz, F Glod, L Veiber, L Mombaerts, ...
The Lancet Regional Health–Europe 4, 2021
1042021
Neural stem cells of Parkinson's disease patients exhibit aberrant mitochondrial morphology and functionality
J Walter, S Bolognin, PMA Antony, SL Nickels, SK Poovathingal, ...
Stem cell reports 12 (5), 878-889, 2019
1002019
Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1−/− zebrafish
S Soman, M Keatinge, M Moein, M Da Costa, H Mortiboys, A Skupin, ...
European Journal of Neuroscience 45 (4), 528-535, 2017
1002017
Fundamental properties of Ca2+ signals
K Thurley, A Skupin, R Thul, M Falcke
Biochimica et Biophysica Acta (BBA)-General Subjects 1820 (8), 1185-1194, 2012
982012
Aneuploidy underlies a multicellular phenotypic switch
Z Tan, M Hays, GA Cromie, EW Jeffery, AC Scott, V Ahyong, A Sirr, ...
Proceedings of the National Academy of Sciences 110 (30), 12367-12372, 2013
862013
Mitochondrial morphology provides a mechanism for energy buffering at synapses
GC Garcia, TM Bartol, S Phan, EA Bushong, G Perkins, TJ Sejnowski, ...
Scientific reports 9 (1), 18306, 2019
822019
Protocols and programs for high-throughput growth and aging phenotyping in yeast
PP Jung, N Christian, DP Kay, A Skupin, CL Linster
PloS one 10 (3), e0119807, 2015
762015
New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome
E Tiraboschi, S Martina, W van der Ent, K Grzyb, K Gawel, ...
Epilepsia 61 (3), 549-560, 2020
692020
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Artikler 1–20