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Sihan Wu
Sihan Wu
Children’s Medical Center Research Institute, University of Texas Southwestern Medical Center
Verifisert e-postadresse på utsouthwestern.edu - Startside
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Circular ecDNA promotes accessible chromatin and high oncogene expression
S Wu, KM Turner, N Nguyen, R Raviram, M Erb, J Santini, J Luebeck, ...
Nature 575 (7784), 699-703, 2019
4592019
Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers
H Kim, NP Nguyen, K Turner, S Wu, AD Gujar, J Luebeck, J Liu, ...
Nature genetics 52 (9), 891-897, 2020
3752020
Altered cellular metabolism in gliomas—An emerging landscape of actionable co-dependency targets
J Bi, S Chowdhry, S Wu, W Zhang, K Masui, PS Mischel
Nature Reviews Cancer 20 (1), 57-70, 2020
2752020
ecDNA hubs drive cooperative intermolecular oncogene expression
KL Hung, KE Yost, L Xie, Q Shi, K Helmsauer, J Luebeck, R Schöpflin, ...
Nature 600 (7890), 731-736, 2021
1972021
Oncogene amplification in growth factor signaling pathways renders cancers dependent on membrane lipid remodeling
J Bi, TA Ichu, C Zanca, H Yang, W Zhang, Y Gu, S Chowdhry, A Reed, ...
Cell metabolism 30 (3), 525-538. e8, 2019
1692019
Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells
M Shu, X Zheng, S Wu, H Lu, T Leng, W Zhu, Y Zhou, Y Ou, X Lin, Y Lin, ...
Molecular cancer 10, 1-17, 2011
1562011
Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers
Y Lin, H Zhang, J Liang, K Li, W Zhu, L Fu, F Wang, X Zheng, H Shi, S Wu, ...
Proceedings of the National Academy of Sciences of the United States of America, 2014
1542014
The anti-Warburg effect elicited by the cAMP-PGC1α pathway drives differentiation of glioblastoma cells into astrocytes
F Xing, Y Luan, J Cai, S Wu, J Mai, J Gu, H Zhang, K Li, Y Lin, X Xiao, ...
Cell reports 18 (2), 468-481, 2017
1142017
MiR-135a functions as a selective killer of malignant glioma
S Wu, Y Lin, D Xu, J Chen, M Shu, Y Zhou, W Zhu, X Su, Y Zhou, P Qiu, ...
Oncogene 31 (34), 3866-3874, 2012
1052012
The evolutionary dynamics of extrachromosomal DNA in human cancers
JT Lange, JC Rose, CY Chen, Y Pichugin, L Xie, J Tang, KL Hung, ...
Nature genetics 54 (10), 1527-1533, 2022
902022
Extrachromosomal DNA: an emerging hallmark in human cancer
S Wu, V Bafna, HY Chang, PS Mischel
Annual Review of Pathology: Mechanisms of Disease 17 (1), 367-386, 2022
822022
Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug
J Bi, A Khan, J Tang, AM Armando, S Wu, W Zhang, RC Gimple, A Reed, ...
Cell reports 37 (5), 2021
732021
Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity
C Zanca, GR Villa, JA Benitez, AH Thorne, T Koga, M D'Antonio, ...
Genes & development 31 (12), 1212-1227, 2017
732017
Extrachromosomal DNA in the cancerous transformation of Barrett’s oesophagus
J Luebeck, AWT Ng, PC Galipeau, X Li, CA Sanchez, ...
Nature 616 (7958), 798-805, 2023
722023
MicroRNA 335 is required for differentiation of malignant glioma cells induced by activation of cAMP/protein kinase A pathway
M Shu, Y Zhou, W Zhu, H Zhang, S Wu, J Chen, G Yan
Molecular pharmacology 81 (3), 292-298, 2012
662012
Emerging function of mTORC2 as a core regulator in glioblastoma: metabolic reprogramming and drug resistance
SH Wu, JF Bi, T Cloughesy, WK Cavenee, PS Mischel
Cancer Biology & Medicine 11 (4), 255-263, 2014
562014
Triptolide cooperates with Cisplatin to induce apoptosis in gemcitabine-resistant pancreatic cancer
W Zhu, J Li, S Wu, S Li, L Le, X Su, P Qiu, H Hu, G Yan
Pancreas 41 (7), 1029-1038, 2012
562012
Single bout short duration fluid shear stress induces osteogenic differentiation of MC3T3-E1 cells via integrin β1 and BMP2 signaling cross-talk
Z Mai, Z Peng, S Wu, J Zhang, L Chen, H Liang, D Bai, G Yan, H Ai
PLoS One 8 (4), e61600, 2013
492013
Inhibition of cancer cell proliferation by midazolam by targeting transient receptor potential melastatin 7
Y Dou, Y Li, J Chen, S Wu, X Xiao, S Xie, L Tang, M Yan, Y Wang, J Lin, ...
Oncology letters 5 (3), 1010-1016, 2013
422013
Activation of a pro-survival pathway IL-6/JAK2/STAT3 contributes to glial fibrillary acidic protein induction during the cholera toxin-induced differentiation of C6 malignant …
M Shu, Y Zhou, W Zhu, S Wu, X Zheng, G Yan
Molecular oncology 5 (3), 265-272, 2011
382011
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Artikler 1–20