| A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility MC Bassik, M Kampmann, RJ Lebbink, S Wang, MY Hein, I Poser, ... Cell 152 (4), 909-922, 2013 | 427 | 2013 |
| Efficient intracellular delivery of native proteins DS D’Astolfo, RJ Pagliero, A Pras, WR Karthaus, H Clevers, V Prasad, ... Cell 161 (3), 674-690, 2015 | 406 | 2015 |
| Attenuation of c GAS‐STING signaling is mediated by a p62/SQSTM 1‐dependent autophagy pathway activated by TBK1 T Prabakaran, C Bodda, C Krapp, B Zhang, MH Christensen, C Sun, ... The EMBO journal 37 (8), e97858, 2018 | 386 | 2018 |
| Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1 RJ Lebbink, T de Ruiter, J Adelmeijer, AB Brenkman, JM van Helvoort, ... The Journal of experimental medicine 203 (6), 1419-1425, 2006 | 386 | 2006 |
| CRISPR/Cas9-mediated genome editing of herpesviruses limits productive and latent infections FR van Diemen, EM Kruse, MJG Hooykaas, CE Bruggeling, AC Schürch, ... PLoS pathogens 12 (6), e1005701, 2016 | 337 | 2016 |
| IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP KL Jønsson, A Laustsen, C Krapp, KA Skipper, K Thavachelvam, D Hotter, ... Nature communications 8 (1), 14391, 2017 | 303 | 2017 |
| Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion TH Huang, F Wu, GB Loeb, R Hsu, A Heidersbach, A Brincat, D Horiuchi, ... Journal of Biological Chemistry 284 (27), 18515-18524, 2009 | 249 | 2009 |
| Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses CK Holm, SH Rahbek, HH Gad, RO Bak, MR Jakobsen, Z Jiang, ... Nature communications 7 (1), 10680, 2016 | 236 | 2016 |
| A combinational CRISPR/Cas9 gene-editing approach can halt HIV replication and prevent viral escape RJ Lebbink, DCM de Jong, F Wolters, EM Kruse, PM van Ham, ... Scientific reports 7 (1), 41968, 2017 | 162 | 2017 |
| The soluble leukocyte-associated Ig-like receptor (LAIR)-2 antagonizes the collagen/LAIR-1 inhibitory immune interaction RJ Lebbink, MCW van den Berg, T de Ruiter, N Raynal, JAG van Roon, ... The Journal of Immunology 180 (3), 1662-1669, 2008 | 148 | 2008 |
| RhoB mediates phosphoantigen recognition by Vγ9Vδ2 T cell receptor Z Sebestyen, W Scheper, A Vyborova, S Gu, Z Rychnavska, M Schiffler, ... Cell reports 15 (9), 1973-1985, 2016 | 146 | 2016 |
| The Sulfolobus solfataricus Lrp-like protein LysM regulates lysine biosynthesis in response to lysine availability AB Brinkman, SD Bell, RJ Lebbink, WM de Vos, J van der Oost Journal of Biological Chemistry 277 (33), 29537-29549, 2002 | 143 | 2002 |
| Rapid creation and quantitative monitoring of high coverage shRNA libraries MC Bassik, RJ Lebbink, LS Churchman, NT Ingolia, W Patena, ... Nature methods 6 (6), 443-445, 2009 | 135 | 2009 |
| A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation ML Van De Weijer, MC Bassik, RD Luteijn, CM Voorburg, MAM Lohuis, ... Nature communications 5 (1), 3832, 2014 | 134 | 2014 |
| Systematic identification of barriers to human iPSC generation H Qin, A Diaz, L Blouin, RJ Lebbink, W Patena, P Tanbun, EM LeProust, ... Cell 158 (2), 449-461, 2014 | 110 | 2014 |
| Identification of multiple potent binding sites for human leukocyte associated Ig-like receptor LAIR on collagens II and III RJ Lebbink, N Raynal, T de Ruiter, DG Bihan, RW Farndale, L Meyaard Matrix biology 28 (4), 202-210, 2009 | 108 | 2009 |
| EBV microrna BART16 suppresses type I ifn signaling MJG Hooykaas, M Van Gent, JA Soppe, E Kruse, IGJ Boer, D Van Leenen, ... The Journal of Immunology 198 (10), 4062-4073, 2017 | 98 | 2017 |
| Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton–Valentine leukocidin AT Tromp, M Van Gent, P Abrial, A Martin, JP Jansen, CJC De Haas, ... Nature microbiology 3 (6), 708-717, 2018 | 93 | 2018 |
| Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI THC Brondijk, T de Ruiter, J Ballering, H Wienk, RJ Lebbink, H van Ingen, ... Blood, The Journal of the American Society of Hematology 115 (7), 1364-1373, 2010 | 92 | 2010 |
| Antiviral goes viral: harnessing CRISPR/Cas9 to combat viruses in humans JA Soppe, RJ Lebbink Trends in microbiology 25 (10), 833-850, 2017 | 90 | 2017 |
Michael T. McManusUniversity of California, San FranciscoVerifisert e-postadresse på ucsf.edu