ashraf brik

Sitert av

	Alle	Siden 2020
Sitater	11033	4278
h-indeks	58	37
i10-indeks	128	94

940

470

235

705

2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202529 53 99 133 180 182 198 284 337 416 494 534 637 805 755 657 827 932 894 803 717 722 208

Offentlig tilgang

Vis alle

54 artikler

3 artikler

tilgjengelige

ikke tilgjengelige

Basert på finansieringsmandater

Medforfattere

Chi-Huey WongThe Scripps Research Institute; Academia SinicaVerifisert e-postadresse på gate.sinica.edu.tw
Muhammad JbaraAssistant Professor of Chemistry - TAUVerifisert e-postadresse på tauex.tau.ac.il
Sachitanand M MaliDirector of ChemistryVerifisert e-postadresse på lilly.com
Ciechanover, ADistinguished Research Professor, Technion-Israel Institute of TechnologyVerifisert e-postadresse på tx.technion.ac.il
Guy Mannסטודנט לדוקטורט בטכניוןVerifisert e-postadresse på campus.technion.ac.il
Hilal LashuelEPFLVerifisert e-postadresse på epfl.ch
Peter SimanIntragel TherapeuticsVerifisert e-postadresse på post.bgu.ac.il
Shay LapsPostdoctoral Scholar, Chou's Lab, Stanford UniversityVerifisert e-postadresse på stanford.edu
Guy KamneskyDoctor of Chemistry, TechnionVerifisert e-postadresse på technion.ac.il
Sumeet K SinghResearch Associate, University of WashingtonVerifisert e-postadresse på uw.edu
Cynthia WolbergerProfessor of Biophysics & Biophysical Chemistry, Johns Hopkins University School of MedicineVerifisert e-postadresse på jhmi.edu
Karthikeyan SVThe Madura College (Madurai)Verifisert e-postadresse på maduracollege.edu.in
David FushmanVerifisert e-postadresse på umd.edu
Mike MorganJohns Hopkins School of MedicineVerifisert e-postadresse på jhmi.edu
Arthur OlsonProfesssor The Scripps Research InstituteVerifisert e-postadresse på scripps.edu
Philip E DawsonThe Scripps Research InstituteVerifisert e-postadresse på scripps.edu
David S. GoodsellThe Scripps Research InstituteVerifisert e-postadresse på scripps.edu
Efrat ShemaDepartment of Immunology and Regenerative Biology, Weizmann Institute of ScienceVerifisert e-postadresse på weizmann.ac.il
Moshe OrenWeizmann Institute of Science, IsraelVerifisert e-postadresse på weizmann.ac.il
Joseph M RogersDepartment of Drug Design and Pharmacology, University of CopenhagenVerifisert e-postadresse på sund.ku.dk

Følg

ashraf brik

Professor of Chemistry

Verifisert e-postadresse på technion.ac.il - Startside

Organic Chemsitry Chemical Biology Protein synthesis


Tittel Sorter etter sitater Sorter etter år Sorter etter tittel	Sitert av Sitert av	År
HIV-1 protease: mechanism and drug discovery A Brik, CH Wong Organic & biomolecular chemistry 1 (1), 5-14, 2003	684	2003
Small molecules targeting severe acute respiratory syndrome human coronavirus CY Wu, JT Jan, SH Ma, CJ Kuo, HF Juan, YSE Cheng, HH Hsu, ... Proceedings of the National Academy of Sciences 101 (27), 10012-10017, 2004	646	2004
1, 2, 3-Triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors A Brik, J Alexandratos, YC Lin, JH Elder, AJ Olson, A Wlodawer, ... ChemBioChem 6 (7), 1167-1168, 2005	386	2005
Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins S Bondalapati, M Jbara, A Brik Nature chemistry 8 (5), 407-418, 2016	346	2016
A copper (I)-catalyzed 1, 2, 3-triazole azide− alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant MJ Giffin, H Heaslet, A Brik, YC Lin, G Cauvi, CH Wong, DE McRee, ... Journal of medicinal chemistry 51 (20), 6263-6270, 2008	295	2008
Highly efficient and chemoselective peptide ubiquitylation KS Ajish Kumar, M Haj-Yahya, D Olschewski, HA Lashuel, A Brik Angewandte Chemie (International ed. in English) 48 (43), 8090-4, 2009	279	2009
Structural basis for histone H2B deubiquitination by the SAGA DUB module MT Morgan, M Haj-Yahya, AE Ringel, P Bandi, A Brik, C Wolberger Science 351 (6274), 725-728, 2016	267	2016
Total chemical synthesis of a 304 amino acid K48-linked tetraubiquitin protein KSA Kumar, SN Bavikar, L Spasser, T Moyal, S Ohayon, A Brik Angewandte Chemie-International Edition 50 (27), 6137-6141, 2011	246	2011
RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation G Fuchs, E Shema, R Vesterman, E Kotler, Z Wolchinsky, S Wilder, ... Molecular cell 46 (5), 662-673, 2012	223	2012
Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors A Brik, J Muldoon, YC Lin, JH Elder, DS Goodsell, AJ Olson, VV Fokin, ... ChemBioChem 4 (11), 1246-1248, 2003	221	2003
The size of the proteasomal substrate determines whether its degradation will be mediated by mono-or polyubiquitylation N Shabek, Y Herman-Bachinsky, S Buchsbaum, O Lewinson, ... Molecular cell 48 (1), 87-97, 2012	203	2012
Total chemical synthesis of di-ubiquitin chains KSA Kumar, L Spasser, LA Erlich, SN Bavikar, A Brik Angewandte Chemie-International Edition 49 (48), 9126-9131, 2010	190	2010
Protein synthesis assisted by native chemical ligation at leucine Z Harpaz, P Siman, KSA Kumar, A Brik ChemBioChem 11 (9), 1232-1235, 2010	170	2010
Synthetic polyubiquitinated α-Synuclein reveals important insights into the roles of the ubiquitin chain in regulating its pathophysiology M Haj-Yahya, B Fauvet, Y Herman-Bachinsky, M Hejjaoui, SN Bavikar, ... Proceedings of the National Academy of Sciences 110 (44), 17726-17731, 2013	162	2013
Efficient palladium‐assisted one‐pot deprotection of (acetamidomethyl) cysteine following native chemical ligation and/or desulfurization to expedite chemical protein synthesis SK Maity, M Jbara, S Laps, A Brik Angewandte Chemie 128 (28), 8240-8244, 2016	156	2016
Sugar-assisted glycopeptide ligation A Brik, YY Yang, S Ficht, CH Wong Journal of the American Chemical Society 128 (17), 5626-5627, 2006	156	2006
Convergent chemical synthesis of histone H2B protein for the site-specific ubiquitination at Lys34. P Siman, SV Karthikeyan, M Nikolov, W Fischle, A Brik Angewandte Chemie-International Edition 52 (31), 8059-8063, 2013	146	2013
Palladium in the chemical synthesis and modification of proteins M Jbara, SK Maity, A Brik Angewandte Chemie International Edition 56 (36), 10644-10655, 2017	145	2017
Chemistry and biology of the ubiquitin signal L Spasser, A Brik Angewandte Chemie International Edition 51 (28), 6840-6862, 2012	145	2012
Towards elucidation of the role of ubiquitination in the pathogenesis of Parkinson's disease with semisynthetic ubiquitinated α-synuclein M Hejjaoui, M Haj-Yahya, K KS, A Brik, HA Lashuel	144	2011

Systemet kan ikke utføre handlingen. Prøv på nytt senere.

Artikler 1–20

Sitater per år

Duplikatsitater

Sammenslåtte sitater

Legg til medforfattereMedforfattere

Følg

Sitert av

Medforfattere